Viewing affirmative mentions of gene expression in T cells

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Wolfgang et al. (2000)TARPT cellTARP: a nuclear protein expressed in prostate and breast cancer cells derived from an alternate reading frame of the T cell receptor gamma chain locus.
Lisi et al. (1993)CR2-likeT cellsExpression of this receptor is restricted to B lymphocytes, some epithelial cells and immature thymocytes; expression of CR2-like proteins has been also found on T cells.
Fattorossi et al. (2002)MUC1T cellsConstitutive and inducible expression of the epithelial antigen MUC1 (CD227) in human T cells.
Duprez et al. (1988)interleukin 2T cellWe have described a human tumor T cell line, IARC 301, which constitutively expresses high affinity interleukin 2 (IL2) receptors, and showed that after binding to its receptors, IL2 is endocytosed and degraded.
Zheng et al. (2006)CCL2T cellModification of the CCL2 DNA vaccine by replacing a surface loop region of CCL2 sequence with tetanus toxoid T helper epitope P30 elicited a strong self-specific CCL2 autoantibody production, as well as an IFN-gamma-producing T cell cellular response.
Park et al. (1998)ASGPRT-cellNonetheless, ASGPR was also detectable on some extrahepatic cells such as the Jurkat T-cell line.
Lu et al. (2002)LFA-1T cellsImportantly, T cells from patients with active lupus have hypomethylated DNA and overexpress LFA-1 on an autoreactive subset, suggesting that the same mechanism could contribute to human lupus.
Friedrich et al. (2006)ART3T cellsThe glycosyl-phosphatidylinositol linkage of ART3 was shown by treating ART3-transfected HEK-293-T cells with phospholipase C.
Chen et al. (1997)RARbeta2T cellThese results suggest that macrophage development and T cell function are affected by antisense expression of RARbeta2, and that anomaly in these cells might be contributing factors to the compromised immune response observed in the AS-RARbeta2 mice.
Gerli et al. (1987)CD38T-cellIncubation with thymic agents induced a significant increases in the CD38+ cell percentage only in the samples with low CD38 antigen expression, and this modulation was mainly attributable to the T-cell subset.
Stoika and Melmed (2002)PTTG mRNAT-cellInhibitors of T-cell functions, such as cyclosporin A and hydrocortisone, decreased induction of PTTG mRNA expression.
Stoika and Melmed (2002)PTTG-1T lymphocytesThese results showed that PTTG-1 expression follows cell cycling patterns in T lymphocytes, providing a convenient model for studying PTTG functions in normal cells.
Agrawal et al. (1998)MUC1T cellsExpression of MUC1 mucin on activated human T cells: implications for a role of MUC1 in normal immune regulation.
Agrawal et al. (1998)MUC1T cellsWe report here that newly synthesized MUC1 is expressed on the surface of mitogen-activated human T cells and is also found in soluble form in the supernatants from cultures of mitogen-activated human T cells.
Agrawal et al. (1998)MUC1T-cellAfter removal of the mitogenic stimulus from the T-cell cultures, MUC1 expression is downregulated.
Delarasse et al. (2003)MOGT cellMoreover, while MOG transcripts are expressed in lymphoid organs in minute amounts, both MOG-deficient and WT mice show similar T and B cell responses against the extracellular domain of MOG, including the immunodominant MOG 35-55 T cell epitope.
Leng et al. (2009)MIFT cellsGlucocorticoid-induced MIF expression by human CEM T cells.
Leng et al. (2009)MIFT cellWe investigated the expression of MIF from the human CEM T cell line, which exists in two well-characterized, glucocorticoid-sensitive (CEM-C7) and glucocorticoid-resistant (CEM-C1) variant clones.
Alirezaei et al. (2009)Atg5T cellsAnalysis of RNA extracted from T cells isolated by negative selection indicated that Atg5 expression was significantly elevated in individuals with active relapsing-remitting MS compared to non-diseased controls.
Alirezaei et al. (2009)Atg5T cellsBrain tissue sections from relapsing-remitting MS cases examined by immunofluorescent histochemistry suggested that encephalitogenic T cells are a source of Atg5 expression in MS brain samples.
Alirezaei et al. (2009)Atg5T cellTogether these data suggest that increased T cell expression of Atg5 may contribute to inflammatory demyelination in MS.
Lorberboum-Galski et al. (1990)IL2T cellsTo produce a molecule that will kill activated T cells as well as lymphomas and leukemias expressing interleukin 2 (IL2) receptors, we have created a recombinant chimeric protein in which IL2 is attached in peptide linkage to a truncated mutant form of Pseudomonas exotoxin (PE) (Lorberboum-Galski, H., FitzGerald, D.J.P., Chandhary, V.K., Adhya, S., and Pastan, I. (1988) Proc.
Lorberboum-Galski et al. (1990)IL2T cellsOur results indicate that IL2-PE664Glu should be evaluated as an immunosuppressive agent for the treatment of human immune disorders in which activated T cells expressing the IL2 receptor are prominent.
Shalitin et al. (1998)hprT-cellTo determine whether the haptoglobin related protein (hpr) affects the growth of an established T-cell leukemia cell line, an Hpr antisense expression vector that specifically reduces hpr production was constructed.
Koga et al. (1988)lckT-cellExpression of the human T-cell-specific tyrosine kinase YT16 (lck) message in leukemic T-cell lines.
Koga et al. (1988)lckT-cellTo evaluate the role of the human T-cell-specific tyrosine kinase lck (YT16), we measured the levels of lck expression in thymocytes, peripheral T-cells, and leukemia T-cell lines which are arrested at different stages of thymic differentiation.
Meijer et al. (2004)L-selectinT cellsReduced L-selectin (CD62LLow) expression identifies tumor-specific type 1 T cells from lymph nodes draining an autologous tumor cell vaccine.
Green and Flavell (2000)TNFalphaT cellsFurther, we have described an interval between 21 and 25 days following initiation of TNFalpha expression where the fate of islet-reactive T cells is decided.
Kats et al. (2002)MIFT lymphocytesIn the present study, immunohistochemical and dual immunofluorescence analyses showed that MIF is effectively expressed by endometriotic tissue, particularly in the glands, and identified endothelial cells, macrophages, and T lymphocytes as cells markedly expressing MIF in the stroma.
Cui et al. (2002)PPARgammaT-cellsThe peroxisome proliferation-activated receptor gamma (PPARgamma) is expressed in many cell types including mammary epithelium, ovary, macrophages, and B- and T-cells.
Martinic et al. (2007)CXCR3T-cellsInterestingly, and in contrast to nucleoprotein-specific CD8 T-cells, IGRP-specific T-cells showed increased CXCR3 expression.
Neudorf et al. (1984)TdtT cellsIn this study we attempted to identify Tdt+ bone marrow cells in man that may be committed to T lineage based on coexpression of Tdt and antigens that have previously been useful in characterization of thymocytes or peripheral-blood T cells.
Mourtada-Maarabouni et al. (2008)GAS5T-cellsConsistent with this, downregulation of endogenous GAS5 inhibits apoptosis and maintains a more rapid cell cycle, indicating that GAS5 expression is both necessary and sufficient for normal growth arrest in T-cell lines as well as human peripheral blood T-cells.
Nihashi et al. (1985)IL2T cellSuch PtLN cells exhibited augmented proliferative responses to T cell mitogens and exogenous interleukin 2 (IL 2) and showed a great ability to produce IL2, which suggests an increase in mature T cells in the PtLN.
Motoya et al. (1997)intercellular adhesion molecule-1T-cellAssociation between expression of intercellular adhesion molecule-1 and integration of human T-cell-leukemia virus type 1 in adult T-cell leukemia cells.
Motoya et al. (1997)intercellular adhesion molecule-1T cellIt is known that the expression levels of intercellular adhesion molecule-1 (ICAM-1) in adult T cell leukemia(ATL) cells are high, whereas those in T-lymphoid cells are not.
Jessop et al. (1995)AVPT cellThymic vasopressin (AVP) transgene expression in rats: a model for the study of thymic AVP hyper-expression in T cell differentiation.
Jessop et al. (1995)AVPT cellThe peptide arginine vasopressin (AVP) is present within tissues of the immune system and has been implicated in T cell differentiation.
Aerts-Toegaert et al. (2007)CD83T cellsCD83 expression on dendritic cells and T cells: correlation with effective immune responses.
Aerts-Toegaert et al. (2007)CD83T cellsIn this study, we wanted to assess the role of CD83 expressed on DC and T cells in the immune response.
Aerts-Toegaert et al. (2007)CD83T cellDown-regulation of CD83 expression on human DC through RNA interference (RNAi) results in a less potent induction of allogeneic T cell proliferation, reduced IFN-gamma secretion by established T cells and decreased capacity in the priming of functional tumor antigen-specific CD8+ T lymphocytes.
Aerts-Toegaert et al. (2007)CD83T cellsIn conclusion, we demonstrate that CD83 expression on T cells and DC modulates the immune response by activating DC and by delivering costimulatory signals for the stimulation of naive and memory T cells, respectively.
Rabinovich et al. (2006)CD19T lymphocytesTo test a potential clinical application of this method, we transfected human T lymphocytes with mRNA encoding a chimeric immune receptor directed against CD19, a surface antigen widely expressed in leukemia and lymphoma.
Jander et al. (1996)VCAM-1 mRNAT cellsIn the acute phase of experimental autoimmune encephalomyelitis and neuritis VCAM-1 mRNA was expressed not only on the luminal surface of inflamed vessels but also in perivascular cells suggesting a functional role of VCAM-1 in both endothelial adhesion and local restimulation of autoantigen-specific T cells.
Jander et al. (1996)VCAM-1 mRNAT cellAccordingly, perivascular T cell accumulation was most pronounced at sites of local VCAM-1 mRNA expression.
Anderson et al. (2000)PLPT cellsThe high frequency of PLP 139-151-reactive T cells in SJL mice is partly due to lack of thymic deletion to PLP 139-151, as the DM20 isoform of PLP (which lacks residues 116-150) is more abundantly expressed in the thymus than full-length PLP.
Tsao et al. (1998)THT cellsThese results suggest that immune T cells express TH which is correlated to cell growth, and that dopamine released from these cells may bind to the receptors to act in an autocrine or paracrine way.
Gillis et al. (1981)TCGFT cellCultures from old donors produced less T cell growth factor (TCGF) and incorporated less tritiated thymidine (3H-Tdr) than did similar cultures from young donors in the presence of either mitogen.
Gillis et al. (1981)TCGFT cellTCGF production or responsiveness was not associated with the presence of "suppressor" activity in elderly T cell preparations.
Inouye et al. (1980)TCGFT lymphocytesTCGF production for cloning and growth of functional human T lymphocytes.
Inouye et al. (1980)TCGFT cellIn an effort to increase the potency of T cell growth factor (TCGF), several variables were examined for their effects on the production of TCGF.
Owen et al. (2005)CCL2T lymphocytesThe expression of CCL2 by T lymphocytes of mammary tumor bearers: role of tumor-derived factors.
Owen et al. (2005)CCL2T cellsOf particular relevance is the finding that tumor-infiltrating T cells also produce high levels of CCL2.
Owen et al. (2005)CCL2T cellsInvestigation of the mechanisms involved in CCL2 induction showed that treatment of splenic T cells with the tumor-derived factors GM-CSF and phosphatidyl serine (PS) resulted in increased CCL2 production.
Teye et al. (2007)Mina53T cellAlthough the expression of Mina53 as well as c-Myc was less frequent in lymphoma compared with those of colon and ESCC, increased expression of Mina53 was found in Burkitt-like lymphoma (1/1), Hodgkin's lymphoma (3/5), diffuse large B cell lymphoma (DLBCL) (5/13), lymphomas with a transition from follicular to DLBCL (1/2), with none in follicular (0/4) and T cell lymphoma (0/3).
Hallet et al. (1991)Macrophage colony-stimulating factorT-lymphocyteMacrophage colony-stimulating factor (CSF-1) gene expression in human T-lymphocyte clones.
Hallet et al. (1991)CSF-1T-cellTogether, these findings demonstrate for the first time that normal T cells are able to produce CSF-1, previous reports being limited to two cases of tumoral cells of the T-cell lineage.
Prat et al. (2005)Flt3T lymphocytesCirculating T lymphocytes were proposed as the main producer of Flt3 ligand.
Yoshizawa et al. (1998)MBPT-cellTo determine what role endogenous MBP expression plays in shaping the BALB/c T-cell repertoire, MBP-deficient BALB/c mice were constructed by breeding the shiverer (shi/shi) mutation onto the BALB/c background.
Yoshizawa et al. (1998)MBPT-cellStudies of the MBP-directed response of these mice suggest that endogenous MBP expression is directly responsible for EAE resistance in BALB/c mice, by quantitatively affecting expression of the T-cell repertoire.
Yoshizawa et al. (1998)MBPT-cellsIn contrast to wild-type BALB/c T-cells, uncloned T-cells from BALB/c shi/shi mice immunized with MBP proliferate in vitro to MBP and MBP peptides 59-76 and 89-101 and are able to induce severe EAE upon transfer to BALB/c recipients expressing MBP.
Bryborn et al. (2008)S100A7T cellsThe S100A7 expression appeared to be the highest in CD8+ T cells.
Levy et al. (1992)CR2T lymphocyteT lymphocyte expression of complement receptor 2 (CR2/CD21): a role in adhesive cell-cell interactions and dysregulation in a patient with systemic lupus erythematosus (SLE).
Corral et al. (2000)KLRG1T cellsKLRG1 is expressed on 30-60% of murine NK cells, and a small fraction of T cells, and is composed of a homodimer of glycosylated 30-38-kDa subunits.
Voehringer et al. (2001)KLRG1T cellsKLRG1 expression was induced in a substantial portion (30-60%) of CD8 T cells in C57BL/6 mice infected with lymphocytic choriomeningitis virus (LCMV), vesicular stomatitis virus, or vaccinia virus.
Houchins et al. (1993)NKG5T cellsWe reported previously the isolation of a cDNA clone, designated NKG5, encoding a secreted protein that is expressed only in natural killer and T cells and is strongly upregulated upon cell activation.
Zheng et al. (1989)CD4T-cellNevertheless, Cr:NIH-nu/nu rats, which are deficient in T-cells, possess virtually identical numbers of CD4 positive staining uterine cells as compared to their nu/+ littermate controls, indicating that the expression of immunoreactive CD4 is associated with a resident non-T-cell population.
Soruri et al. (2004)HDM2T cellsIn vitro generation of cytolytic T cells against human melanoma cells overexpressing HDM2.
Marcet-Palacios et al. (2007)WT1T cellUsing the proliferative compound PHA we induced T cell proliferation and growth correlated with an increase in the expression of WT1 measured by RT-PCR, flow cytometry and immunoblot.
Collins et al. (1990)TCGFT-cellAnti-human IL-2 partially blocked the T-cell growth factor (TCGF) activity produced by these hybrids.
Honda et al. (1988)parathyroid hormone-related proteinT-cellProduction of parathyroid hormone-related protein in adult T-cell leukemia cells.
Kaplan et al. (1988)IL-2T cellsAlthough it is possible that the epitopes seen were present on a distinct molecule independent of secreted IL-2, the distribution on a variety of T cells and regulation via cellular activation suggest that the surface expression of IL-2 epitopes is in some way related to the soluble lymphokine.
Hua et al. (1999)CTLA4IgT-cellAs Mm1 cells were regarded as difficult for gene transfection and there had so far been no report on expression of CTLA4Ig gene on Mm1 cells, these results suggested that the CTLA4Ig expressing Mm1 cells could be useful for analysis of CTLA4 and B7 molecule interaction in both macrophage and T-cell.
Cappellesso et al. (2002)FasLT-cellsSeveral studies have shown that immune-privileged sites express Fas ligand (FasL) and induce apoptosis of activated T-cells.
Cappellesso et al. (2002)FasLT cellWe propose that endothelial cells engineered to express FasL could inhibit alloreactive T cell-proliferation by inducing apoptosis.
Cappellesso et al. (2002)FasLT-cellUsing a mixed lymphocyte-endothelial cell culture model we observed that FasL-transfected ECV304 cells which conserved their two principal costimulatory pathways inhibited alloreactive T cell-proliferation by inducing activated T-cell apoptosis.
Lechner et al. (1996)CD95T cellsRegulation of CD95 (APO-1) expression and the induction of apoptosis in human T cells: changes in old age.
Lechner et al. (1996)CD95T lymphocytesIn view of the known decline of immune function in old age it seemed of interest to study the expression and inducibility of CD95 in peripheral blood T lymphocytes from young and old healthy subjects selected according to the guidelines laid down in the Senieur protocol of the European Community's Concerted Action Programme on Aging.
Lechner et al. (1996)CD95T cellT cell activation by anti-CD3 monoclonal antibody (OKT3) did, however, lead to a rapid increase in the number of CD95 expressing cells.
Lechner et al. (1996)CD95T cellUnder long-term culture conditions T cell lines derived from both young and old individuals progressively lost the capacity to decrease the expression of CD95 at the end of their activation cycle and an increasing susceptibility to activation-driven programmed cell death was noted.
Glass et al. (2001)CCR5T cellHowever, by day 12 pi, T cell infiltration into the CNS of infected CCR5(-/-) and CCR5(+/+) mice was similar and both strains exhibited comparable viral titers, indicating that CCR5 expression is not essential for host defense.
Yasuda et al. (2007)RasGRP1 proteinT cellT cell lysates from healthy controls and SLE patients also were evaluated for their levels of RasGRP1 protein.
Wykes et al. (2002)CD227T cellsAdditionally, we confirm CD227 expression by activated human T cells and show for the first time that the CD227 cytoplasmic domain is tyrosine-phosphorylated in activated T cells and DC and is associated with other phosphoproteins, indicating a role in signaling.
Stärck et al. (2005)CD80T-cellNecrotic death but not irradiation abolishes costimulation of T-cell effector functions and survival by CD80-expressing tumor cells.
Stärck et al. (2005)CD80T cellsIn contrast, necrosis of gene-modified tumor cells abrogates costimulation of T cells by CD80-expressing cells.
Taylor and Giesbrecht (2000)p56lckT lymphocyteOne of the major recent findings is that murine splenic T lymphocyte p56lck expression is elevated in dietary Zn deficiency and caloric deficiency.
Willett et al. (2003)CXCR4T lymphocytesWhile monocytes and B lymphocytes expressed CXCR4, no CXCR4 was detected on T lymphocytes, in stark contrast to the expression pattern on T lymphocytes from humans.
Muta et al. (2004)RCAS1T-cellExpression of human tumor-associated antigen RCAS1 in adult T-cell leukemia/lymphoma.
Muta et al. (2004)RCAS1T-cellsIn human cancer, RCAS1 (the receptor-binding cancer antigen expressed on SiSo cells) on the surface of various kinds of tumor cells reportedly induces the apoptosis of T-cells and natural killer cells, resulting in evasion of the immune system.