Viewing negative mentions of binding of IL2 (H. sapiens) and IL2RB (H. sapiens)

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Document Target Regulator Anatomy Sentence
de Jong et al. (1996)IL-2RIL-2Proliferation of anti-CD3 (OKT3)-stimulated human PBL was compared for responsiveness to IL-2, IL-15, and F42K, and IL-2 mutant that does not bind the IL-2R alpha chain.
Heaton and Grimm (1995)IL-2RIL-2We assessed the roles of the various receptor complexes in these responses to IL-2 using antibodies that block the interaction of IL-2 with the intermediate-affinity IL-2R (humanized Mik beta 1) and high- and low-affinity interactions (HTac).
Chu and Sharom (1993)IL-2RIL-2The glycolipids also prevented chemical cross-linking of [125I]IL-2 to the p55/p75 complex, as well as to both IL-2R alpha (p55) and IL-2R beta (p75) independently.
Chu and Sharom (1993)IL-2RIL-2Taken together, these findings indicate that gangliosides directly block the interaction of IL-2 with IL-2R, and may explain, in part, the immunosuppressive activities of gangliosides in vivo.
Colamonici et al. (1990)IL-2RIL-2We propose that p95-110 is the partner of p75 in the formation of intermediate affinity IL-2R, inasmuch as neither p75 nor p95-110 alone can bind IL-2.