Document | Target | Regulator | Anatomy | Sentence |
---|---|---|---|---|
Jadus et al. (1991) | IL2 | LAK cells | However, when the serum free medium, Aim V, was used, IL4 did generate LAK cells (eight out of nine patients), although not as cytotoxic as those activated with IL2. | |
Stötter and Lotze (1991) | IL-2 | LAK cell | Our studies of the processes involved using 21-mer phosphorothioate antisense oligonucleotides to the sequence adjacent to the start codon of IL-2 mRNA or IL-4 mRNA (effective concentration, 5 to 10 mumol/L) and cyclosporine (0.01 to 1.0 microgram/mL) or FK506 (0.01 to 1.0 ng/mL) demonstrate that IL-7-induced LAK cell activity is independent of IL-2 production and is regulated by endogenously generated IL-4. |