Viewing negative mentions of negative regulation of Cd4 (M. musculus) in T cells

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Bensinger et al. (2001)CD4T cellsIn contrast, CD4(+)25(+) T cells from MHC class II-deficient mice do not suppress responder CD4(+) T cells in vitro or in vivo.
Ermann et al. (2001)CD4T cellCD4(+)CD25(+) T cell-induced suppression, in this model, was not abrogated by blocking the B7-CTLA-4 pathway.
Anderson and Fritsche (2004)CD4T-cellSurprisingly, (n-3) PUFA consumption did not reduce CD4(+) T-cell expansion.
Subauste et al. (1991)CD4T lymphocytesThe effector cells were shown to be CD8+ T lymphocytes, because the cytotoxicity was significantly inhibited by depletion of CD8+ T lymphocytes but not by depletion of CD4+ T lymphocytes.
Xu et al. (2002)CD4T cellsIn this study, we show that protective parasite-specific CD4(+) T cells were depleted after infection with both lethal and nonlethal species of rodent PLASMODIUM: It is further shown that the depletion is confined to parasite-specific T cells because (a) ovalbumin (OVA)-specific CD4(+) T cells are not depleted after either malaria infection or direct OVA antigen challenge, and (b) the depletion of parasite-specific T cells during infection does not kill bystander OVA-specific T cells.
Hu et al. (2003)CD4T-cellOn the contrary, T-cell proliferation was significantly reduced in the CD8 subset but not in the CD4 subset in recipient mice treated with rapamycin.
Hoyne et al. (1996)CD4T cellsMice deficient in CD8+ T cells became tolerant by i.n. treatment with peptide, suggesting that CD8+ T cells are not involved in down-regulating the CD4+ T cell response.
Ly et al. (2006)CD4T-cellsSurprisingly, the number of surface CD28 molecules was not reduced in activated CD4(+) T-cells from either group of n-3 PUFA-fed mice.
Wallace et al. (1993)CD4T-cellRecent data also demonstrate that the requirement for CD4 and CD8 in negative selection of T cells is not absolute and may be regulated by T-cell receptor affinity for the deleting ligand, an interpretation consistent with the affinity model of thymic selection.
Visciano et al. (2008)CD4T cellThese data are consistent with in vitro data shown in Fig. 2 with a mouse CD4 T cell clone and with previously published results with a number of human CD4 T cell lines [1,2,8,12] demonstrating that the CD4 T cell proliferative responses to gp120 are suppressed in the presence of anti-CD4bs mAbs, but not other anti-gp120 or control mAbs.
Tsukamoto et al. (2010)CD4T cellsHowever, newly generated Bim(+/-) naive CD4 T cells in middle-aged mice are not defective, indicating an additional requirement for their persistence in the periphery.
Homma et al. (2005)CD4T cellsAntitumour activity induced by DC/BNL + IL-12 was abrogated by depletion of CD4+ T cells, but not by depletion of CD8+ T cells or natural killer cells.
Kremer et al. (2000)CD4T cellsIn vitro addition of neutralizing anti-TNF-alpha antibodies led to a significant reduction in CD3-induced T-cell apoptosis of both CD4(+) and CD8(+) T cells of C57BL/6 mice, while the blockade of Fas-FasL interactions reduced apoptosis only in CD4(+) but not in CD8(+) T cells.
Lu et al. (2008)CD4T cellEvaluation of splenocytes of antibody-treated animals showed no reduction in the CD4+ T cell population (data not shown).
Kijima et al. (2009)CD4T cellHowever, this treatment did not suppress CII-specific CD4(+) T cell proliferation and CII-specific Ab production.
Keogh and Limper (2005)CD4T cellHowever, the prevalence of B and T cell populations in NSIP, and specifically the CD4 or CD8 T cell content has not been fully defined in this disorder.
Browne et al. (2009)CD4T cellSimilarly, the CD4+ T cell response to F-MLV was reduced but not absent in Myd88 knockout mice.
Kakimi et al. (2000)CD4T cellsIn addition, prior antibody-mediated depletion of CD4(+) and CD8(+) T cells from the mice did not diminish the ability of alpha-GalCer to trigger the disappearance of HBV from the liver, indicating that conventional T cells were not downstream mediators of this effect.
Sasaki et al. (2010)CD4T cellsInterestingly, the tumor bearing condition did not suppress miR-17-5p expression by CD4+ T cells in STAT6-/- mice.
Marathias et al. (1994)CD4T cellsCD4 expression on pulmonary T cells did not increase after 72 hours of ex vivo culture in complete medium but was restored toward control levels by stimulation with phytohemagglutinin, anti-CD3, or interleukin-2.
Miyagi et al. (2005)CD4T cellsThe protective effect of CpG-ODN, as shown by the prolonged survival, was completely and partially inhibited by depletion of CD4(+) or CD8(+) T cells, respectively, but not by depletion of other cells.
Priyadharshini et al. (2010)SMARTA-CD4T cellsIn contrast, P14 -CD8+ donor T cells in mice that were infected with GP1V mutant virus were impaired in their ability to produce TNF (Fig. 3A) while SMARTA-CD4+ donor T cells were unaffected.
Suzuki et al. (2005)CD4T cellsRESULTS: This study shows that the chemotherapeutic drug gemcitabine, given at a dose similar to the equivalent dose used in patients, was able to dramatically and specifically reduce the number of myeloid suppressor cells found in the spleens of animals bearing large tumors with no significant reductions in CD4(+) T cells, CD8(+) T cells, NK cells, macrophages, or B cells.