Viewing affirmative mentions of gene expression of IL2RA (H. sapiens) in T cells

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Prince et al. (1988)sIL2RT-cellThese findings indicate that the in vitro T-cell activation defects which characterize HIV infection include decreased sIL2R production, as well as decreased cellular IL2R expression and DNA synthesis.
Macera et al. (1992)IL2RT-cellsThe alpha-chain of the IL2R is continuously expressed on affected T-cells in this disease.
Célérier et al. (1992)CD25T-cellThe CD25 (IL-2-R alpha) cell surface glycoprotein expressed transiently during T-cell activation is implicated in the high affinity IL-2 receptor.
Schoel et al. (1996)CD25T-cellActivated T-cell express CD25, the p55 chain of the IL-2 receptor.
Woerly et al. (1996)CD25T lymphocytesThis study has investigated the effect of rapamycin on mRNA levels of CD25 and membrane expression of IL-2 receptor in human primary T lymphocytes activated by various stimuli.
Miyatake and Maeda (1997)CD25T cellThe effects of retinoic acid (RA) on the cell growth and expression of interleukin-2 (IL-2) receptors (IL-2R alpha/p55, Tac, CD25) by the human T lymphotropic virus type I (HTLV-I)-positive T cell lines, HUT102 and ATL-2 were investigated.
Ladányi et al. (2004)interleukin 2 receptor alphaT-cellWe investigated the expression of two T-cell activation markers, interleukin 2 receptor alpha (CD25) and OX40 (CD134), by immunohistochemistry in primary cutaneous melanoma samples of 76 patients and analyzed it in relation to tumor stage and tumor progression (>5 years follow-up), as well as to patients' survival.
Ryffel et al. (1995)IL-2RT-lymphocyteWe investigated the transcription and expression of the interleukin-2 receptor (IL-2R, CD25) in human T-lymphocytes after different modes of T-lymphocyte stimulation in the presence of the immunosuppressants cyclosporin (CsA) and tacrolimus (FK506) as well as the structurally related macrolide rapamycin.
Mori et al. (1992)CD25T cellsFurthermore, the factor significantly inhibited the expression of CD3, CD4, and IL-2 receptor (IL-2R) alpha-chain (CD25) on PHA-stimulated T cells.
Alard et al. (1993)IL-2 receptorT cellsIn order to evidence anergy, we studied two activation markers (cell size increase and expression of IL-2 receptor [CD25]) in allografted recipient T cells after autologous (background), donor (experimental), and third-party cell stimulation (positive control).
Prince and Jackson (1990)CD25T cellDysregulated expression of the p55 interleukin 2 receptor (CD25) is characteristic of adult T cell leukemia (ATL) associated with human T lymphotropic virus (HTLV) infection.
Grönwall et al. (2008)CD25T-cellMoreover, CD25 has been found to be overexpressed in organ rejections, a number of autoimmune diseases and T-cell malignancies.
Berry et al. (1990)interleukin 2 receptorT cellsPurified resting human T cells can be induced to express the alpha subunit of the interleukin 2 receptor and to proliferate by treatment with 12-O-tetradecanoylphorbol-13-acetate plus ionomycin but not with 1,2-dioctanoylglycerol plus ionomycin.
Berry et al. (1990)interleukin 2 receptorT-cellDelivery of multiple additions of 1,2-dioctanoylglycerol plus ionomycin to the T cells resulted in progressively increased expression of the alpha subunit of the interleukin 2 receptor and proliferation commensurate with the number of multiple additions delivered, suggesting that prolonged protein kinase C activity is required for T-cell activation.
Alexander et al. (1993)IL2RT-cellsThe proliferative unresponsiveness was not related to low expression of CD3 or IL2R beta as the percentage of T-cells expressing CD3 and IL2R beta were comparable in both T-TIL and peripheral blood T-cells obtained from the same patient.
Moiré et al. (1990)IL2RT cellWe have examined the role of isolated interleukin 2 receptor (IL2R) beta chains expressed by human resting T cells in the early period of primary T cell activation induced by soluble OKT3 monoclonal antibody (mAb) and exogenous IL2.
Treiber-Held et al. (1996)CD25T cellsWhen isolated T cells or non-T cells were stimulated by rIL-15 or rIL-2, cell surface CD25 was expressed, but released sIL-2R alpha was undetectable.
Bell et al. (1993)CD25T cellsCD25 (Tac, p55), the alpha chain of the interleukin 2 receptor, is expressed on activated, but not quiescent, T cells.
González-Fernández et al. (1991)IL2RT cellsPre-thymocytes respond to PBu2 in a way similar to T cells, being able to secrete IL2 in significant amounts and express the p55 chain of IL2R.
Meloni et al. (2004)CD25T cellsRESULTS: The frequency of CD4+ T cells expressing CD25 (CD4+CD25+) and the highest levels (CD25) were lower in patients with bronchiolitis obliterans syndrome compared with healthy subjects and subjects in a stable clinical condition (P < or = 0.01).
Uranchimeg et al. (2010)IL-2RT-cellSakaguchi et al. (1995) rekindled interest in the concept of T-cell-mediated suppression in the mid-1990s by showing that a minor population (~10%) of CD4+ T cells, which co-expresses the interleukin-2 receptor (IL-2R) ?
Vuitton and Gottstein (2010)CD 25T-cellsAnalysis of the cell surface markers of the epithelioid macrophages lining the parasitic vesicles in humans (Figure 2(a)) has shown a very unusual expression of these markers, particularly a high expression of CD 25, the inducible chain of the IL-2 receptor, a chain usually only expressed by activated T-cells and especially CD4 T-regulatory cells [99].
Bagchi et al. (2010)IL2RalphaT cellCD4(+) T-cell activation together with HLA-DR is associated with the expression of CD25(+) (IL2Ralpha) for IL-2 growth factors with decreased IL-4 levels, required for maintaining the homeostasis of CD4(+) T cell.
Roessler et al. (2008)CD25T cellsThe expression of CD4(+)CD25(+) T cells was similar in healthy subjects and AD patients.
Venken et al. (2008)CD25T cellsOur data revealed a reduced number of peripheral blood CD4+ CD25(high) FOXP3+ T cells and lower FOXP3 protein expression per cell in RR-MS patients than in SP-MS patients and control individuals, which was correlated with the suppressive capacity of Tregs in these patients.
Zhang et al. (2008)CD25T cellsThe mechanism might be the effect of CsA on the T cells activation because the expression of CD69 and CD25 molecules on T cells was markedly reduced in the presence of CsA.
Shu et al. (2008)CD25T cellsThis study was aimed to investigate the expression level of CD4(+) CD25(high) T cells in peripheral blood of patients with idiopathic thrombocytopenic purpura (ITP) before and after treatment and to explore its significance in pathogenesis of ITP.
Shu et al. (2008)CD25T cellsThe expressions of CD4(+) CD25(high) T cells in peripheral blood of 20 ITP patients before treatment, 20 ITP patients after treatment and 14 normal individuals (control) were detected by immunofluorescence and flow cytometry.
Shu et al. (2008)CD25T cellsIn conclusion, the expression of CD4(+) CD25(high) T cells in the ITP group before treatment was evidently lower than that in the control group, which becomes higher than before when the patients showed effective response to the treatment.
Solomou et al. (2007)CD25T cellsTransfection of FOXP3-deficient CD4(+)CD25(+) T cells from patients with a plasmid encoding wild-type NFAT1 resulted in increased FOXP3 expression in these cells.
Phillips et al. (2007)CD25T cellsActivated T cells express the high affinity interleukin 2 receptor (IL-2R also CD25) that binds interleukin 2 (IL-2) and transduces signals important for the proliferation and survival of these cells.
Gumá et al. (2005)IL-2RalphaT cellsCoculture with the 721.221 HLA class I-deficient lymphoma cell line transfected with HLA-E (.221-AEH) induced IL-2Ralpha expression in CD94/NKG2C+ NK cells and a minor subset of CD94/NKG2C(+) T cells, promoting their proliferation; moreover, a similar response was triggered upon selective engagement of CD94/NKG2C with a specific mAb.
Gumá et al. (2005)IL-2RalphaT cellSpecific engagement of the KLR triggered cytotoxicity and cytokine production in CD94/NKG2C(+) T cell clones, inducing as well IL-2Ralpha expression and a proliferative response.
Celli et al. (2005)IL-2RalphaT cellImportantly, signals that are delivered during subsequent DC contacts are integrated by the T cell and promote sustained IL-2Ralpha expression and IFN-gamma production.
Reddy et al. (2005)IL-2RalphaT lymphocytesOur results indicate that CLA expression on activated T lymphocytes is IL-12 and activation dependent and correlates with the expression of IL-12 receptors, IL-2Ralpha, and CXCR3.
Nokiba (2005)CD 25T cellsThe expressions of CD 4, CD 8, CD 25, and CLA of metal-specific T cells were determined by flow cytometric analysis (FACS).
Thomachot et al. (2004)CD25T cellsThe absolute number of T cells was reduced by 50% in both the CD4+ or CD8+ compartments, these T cells expressing lower levels of the CD25 Ag and producing less IFNgamma.
Hamzaoui et al. (2002)CD25T cellsIn asthmatic patients, there is a significantly increased proportion of T cells expressing CD69 and CD25 antigen.
Marriott et al. (2002)CD25T lymphocytesThe extent of co-stimulation by Thd/IMiDs (assessed by CD69/CD25 expression and IL-2/sIL-2Ralpha production) was similar for CD4+ and CD8+ T lymphocytes and correlated with TNFR2 inhibition.
Wu and Xu (2000)CD25T cell[Effect of transforming growth factor - beta1 on expression of CD69(+) and CD25(+) T cell induced by allo - corneal epithelial cells in vitro].
Canaday et al. (1999)IL-2RalphaT cellsStimulation of T cells from healthy tuberculin skin test-positive persons with live M. tuberculosis-H37Ra or soluble M. tuberculosis Ags readily up-regulated IL-2Ralpha (CD25) expression on CD8+ T cells.
Toyoda et al. (1999)CD25T-cellWe studied the expression of interleukin-2 receptor alpha (CD25)+ CD45RO+ CD4+ T lymphocytes (T-cell activation) in response to the rubella virus (RV) antigen (Matsuura strain, Biken, Osaka, Japan) using three-color-staining flow cytometry.
Zubiaur et al. (1999)CD25T cellHowever, in cells expressing chimerical CD25-zeta or CD25-epsilon receptors or in a TCR-beta- Jurkat T cell line, CD38 ligation did not result in tyrosine phosphorylation of the chimeric receptors, or CD3 subunits, or protein-tyrosine kinase or mitogen-activated protein kinase activation.
Foley et al. (1998)IL-2RalphaT cellSince IL-2Ralpha expression is an early marker of T cell activation, we investigated: (1) if an increase in sIL-2R is specific for acute GVHD; and (2) if serial sIL-2R levels can identify patients with early GVHD, prior to the onset of clinical tissue damage (effector function).
Kremer et al. (1998)IL-2RalphaT cellsAddition of IFN-gamma induced CD40 and B7-1 expression on UV-Mphi and restored IL-2Ralpha expression on UV-Mphi-activated T cells but had no effect on IL-2Ralpha on resting or LC-activated T cells.
Kremer et al. (1998)IL-2RalphaT cellsThe restoration of IL-2Ralpha expression on UV-Mphi-activated T cells by IFN-gamma was inhibited (67 %, p = 0.005) by addition of neutralizing anti-CD40.
Benito et al. (1997)CD25T lymphocytesQuantitative alterations of the functionally distinct subsets of CD4 and CD8 T lymphocytes in asymptomatic HIV infection: changes in the expression of CD45RO, CD45RA, CD11b, CD38, HLA-DR, and CD25 antigens.
Kahn-Perlès et al. (1997)IL-2RalphaT lymphocytesStimulation of highly purified primary T lymphocytes through CD2 and CD28 adhesion molecules induces a long-term proliferation, dependent on persistent autocrine secretion of interleukin 2 (IL-2), high and prolonged expression of inducible CD25/IL-2 receptor alpha chain (IL-2Ralpha), and secretion of growth factors such as the granulocyte-macrophage colony-stimulating factor (GM-CSF).
Sidell et al. (1997)IL-2RT-cellAs a cell line model for studying this phenomenon, we tested the effects of retinoic acid (RA) on the expression of IL-2Ralpha and IL-2Rbeta in Hut78 cells, a mature T-cell line derived from a Sezary T-cell leukemia.
Bonno et al. (1996)IL-2RT lymphocytesAfter a 6-day culture with or without Dermatophagoides farinae (Df) antigen, the expression of IL-2Rp55 (CD25) and p75 on CD4+ or CD8+ T lymphocytes was measured by flow cytometry.
Laso et al. (1996)CD25T-cellsThus, a progressive and significant expansion (P < 0.05) of CD4+ T-cells associated with an increased expression of the CD25 activation-related antigen and a preferential use of the CD45R0 isoform by CD4+ T-cells were observed.
Shi et al. (1995)CD25T-cellSeventy-three T-cell clones (TCC) were established from tumour-infiltrating lymphocytes-T (TIL-T) derived from lymph nodes involved by B-cell non-Hodgkin's lymphomas (B-NHL) in nine patients with different histological subtypes and clinical stages. 40 TCC (55%) expressed the CD25 Ag and were also able to proliferate in the presence of irradiated autologous B-NHL cells.
Lewis et al. (1994)anti-TACT-lymphocytesCharacterization of a humanized monoclonal antibody (Hu-anti-TAC) directed against a surface protein expressed on T-lymphocytes was performed with an electrospray mass spectrometer.
Ammar et al. (1993)IL2RT cellsWe recently reported that HIV-infected adherent cells spontaneously produce a 29-kDa protein (p29), most probably of nonviral origin, which inhibits expression of the IL2R alpha chain on activated normal T cells.
Sakamoto et al. (1991)CD25T cellsImmunohistochemically, the choroidal infiltrate was composed predominantly of T lymphocytes with a larger proportion of helper/inducer T cells than suppressor/cytotoxic T cells and it also included activated lymphocytes expressing CD26 and CD25 antigens.
Winter et al. (1991)CD-25T-cellWe report an unusual case of childhood Ki-1 lymphoma that presented as a buttock mass in an eight-year-old girl, Pathologic evaluation revealed the characteristic lymphoma cells expressing Ki-1 antigen (CD-30), HLA-DR, interleukin 2 (CD-25), T-cell gene rearrangement, and the cytogenetic karyotype t(2;5).
Jackson et al. (1990)CD25T cellsRestricted expression of p55 interleukin 2 receptor (CD25) on normal T cells.
Butcher et al. (1990)TacT cellsIL-4 could not promote Tac expression on high-density T cells prepared from the same tissue source.
Larsen (1990)IL-2RT-cellIn contrast T cells incubated with ionomycin were induced to produce IL-2 and express IL-2Rs upon brief exposure to PDBu with a 2-h incubation period being sufficient for maximal T-cell activation.
Kernohan et al. (1990)CD-25T cellsThe presence of NK cells in association with some cases of CMM bears no clear relationship to the Breslow thickness, Clark level, tumour ulceration, or the presence of activated T cells as determined by expression of the CD-25 antigen.
Lai et al. (1988)CD25T-lymphocyteThe present study was undertaken to examine the expression of interleukin-2 receptor (IL-2R)/CD25 antigen in cultured T-lymphocyte subsets in IgA nephropathy.
Pedersen et al. (1987)CD25T-lymphocyteAll T-lymphocyte colonies obtained from unseparated peripheral blood mononuclear cells expressed the CD25 antigen (IL-2 receptor) and colonies were always composed of either CD4+ or CD8+ cells.
Sugimura et al. (1989)IL2RT lymphocytesThus, this study elucidated that LBIF arrests PHA-stimulated T lymphocytes at a point between the stages of IL2 production or IL2R light chain expression (in early G1) and transferrin receptor expression (in late G1).
Orson et al. (1989)CD25T cellsThese results indicate that in healthy older individuals, diminished numbers of T cells can be induced to express cell surface IL-2R following mitogenic stimulation, although aged CD25+ can express a normal complement of IL-2R molecules.
Narumiya et al. (1987)IL-2-RT-cellFK also enhanced the IL-2-R expression on a human T lymphotrophic virus I (HTLV-I) positive T-cell line (YTA-1H) and augmented the phorbol ester-induced expression of IL-2-R on HTLV-I negative T-cell lines (HSB-2 and HPB-ALL).
Levings et al. (2002)CD25T cellsSeveral types of Tr cells exist, including CD4(+) T cells which express CD25 constitutively and suppress immune responses via direct cell-to-cell interactions, and type 1 T regulatory (Tr1) cells, which function via secretion of interleukin (IL)-10 and transforming growth factor (TGF)-beta.
Levings et al. (2002)CD25T cellCloned human CD25(+)CD4(+) T cell populations are heterogeneous and only a subset of clones continues to express high levels of CD25 and is suppressive.
Levings et al. (2002)CD25T cellThe intensity of CD25, cytotoxic T lymphocyte antigen (CTLA)-4, and glucocorticoid-induced tumor necrosis factor (TNF) receptor expression correlates with the suppressive capacity of the T cell clones.
Levings et al. (2002)CD25T cellSuppression mediated by CD25(+)CD4(+) T cell clones is partially dependent on TGF-beta, but not on constitutive high expression of CD25.
Sahraoui et al. (1992)IL2RT-cellIn order to determine the role of interleukin 2 (IL2) on the proliferation of leukemic cells from patients with T-cell acute lymphoblastic leukemia (T-ALL) we studied the production of IL2, the function of IL2 receptors (IL2R) expressed on T-ALL cells and their IL-2-dependent in vitro proliferation.
Bjorndahl et al. (1989)IL2RT cellsMonoclonal antibodies (mAb) against CD3 or CD28 in conjunction with the tumor promoter phorbol 12-myristate 13-acetate (PMA) induce interleukin 2 receptor (IL2R) expression, IL2 production and proliferation in resting T cells.
Matthews et al. (2004)CD25T cellsBAY 50-4798 induced dose-dependent increases in CD25 expression and proliferation of T cells, NK, and B cells and showed selectivity for CD4 T cells expressing CD25.
Teshigawara et al. (1985)IL-2-RT-cellHuman T-cell leukemia virus (HTLV)-infected cell lines derived from adult T-cell leukemia (ATL) express constitutively the receptor for Interleukin-2 (IL-2-R) and the associated antigen (Tac antigen).
Teshigawara et al. (1985)IL-2-RT-cellsSince the antigen was modulated on normal mitogen- or alloantigen-stimulated T-cells, we postulated that the regulation of IL-2-R may be abnormal on ATL cells; the synthesis of IL-2-R is continuously stimulated in these cells.
Bonnefoy-Berard et al. (1992)CD25T-cellInhibition of CD25 (IL-2R alpha) expression and T-cell proliferation by polyclonal anti-thymocyte globulins.
Bonnefoy-Berard et al. (1992)CD25 proteinT-cellSuppression of T-cell proliferation by ATG was characterized by normal RNA synthesis and IL-2 secretion contrasting with markedly reduced expression of the CD25 protein [p55, the alpha-chain of interleukin-2 receptor (IL-2R)] both in cytoplasm and on T-cell membrane, as well as a decreased secretion of interferon-gamma (IFN-gamma).
Bonnefoy-Berard et al. (1992)CD25T-cellThese data demonstrate that inhibition of T-cell proliferation by ATG can be attributed primarily to a post-transcriptional defect of CD25 expression, implying a novel mechanism different from those described with other immunosuppressive agents.
Baecher-Allan and Hafler (2006)CD25T cellsRegulatory T cells were initially identified and isolated in the mouse, by virtue of their endogenous expression of CD25 (IL-2R alphachain) and shown to inhibit both the in vivo development of autoimmunity and the in vitro proliferation of nonregulatory, CD4+CD25- T cells.
Baecher-Allan and Hafler (2006)CD25T cellsSuch cells can be isolated by targeting only the small percentage of human CD4 T cells that express high levels of CD25.
Baecher-Allan and Hafler (2006)CD25T cellsThis is best achieved by FACS sorting using the level of CD25 expressed on CD4- T cells to place the gate for discriminating high expression of CD25.
Coventry et al. (1996)IL-2RT cellsThis strongly indicates that the TIL are an activated population of T cells that shows a deficiency in IL-2 protein and IL-2R expression despite adequate levels of IL-2 mRNA.
Mathan et al. (2006)IL2RT cellThe expression of interleukin 2 (IL2) and IL2R, as shown immuno-histochemically, is the final step in T cell mediated acute renal allograft rejection.
Kaestel et al. (2002)IL2RT cellsThe inhibition of the T cells' proliferation correlates with a decreased expression of IL2R-beta and -gamma chains.
Kaestel et al. (2002)IL2RT cellsThe T cells regain their ability to proliferate and increase their IL2R-beta and -gamma chain expression within 24 hr after removal from the coculture.
Macciò et al. (2008)CD25T-cellEvidence that human serum with high levels of estrogens interferes with immune system both by decreasing CD25 expression on T-cell and by increasing interleukin-2 availability.
Batuman et al. (1994)interleukin-2 receptorT cellsGlucocorticoid-mediated inhibition of interleukin-2 receptor alpha and -beta subunit expression by human T cells.
Batuman et al. (1994)interleukin-2 receptorT cellTo determine the mechanism of glucocorticoid (GC)-mediated inhibition of T cell functions, the effect of dexamethasone (DM) on T cell proliferation and interleukin-2 receptor (IL-2R) generation were studied.
Santos et al. (1991)interleukin-2 receptorT lymphocyteIn our search for an alternative, we examined the feasibility of determining T lymphocyte activation by measuring interleukin-2 receptor (CD25) expression with flow cytometry.