Viewing affirmative mentions of gene expression of IFN1@ (H. sapiens) in T cells

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Giacomini et al. (2011)IFNT cellsIndeed, NK and T cells are recruited after Mtb infection and produce IFN-?
Semple et al. (2011)IFNT-cellsRecently, Murray et al. showed that BCG vaccination induced specific CD8+ T-cells which produced IFN-?
Meraviglia et al. (2011)IFNT cellsT cells show a high production of IFN-?
Meraviglia et al. (2011)IFNT-cellT-cell clones produced IFN-?
Wei et al. (2011)IFNT-cellsCytokines produced by T-cells, such as IFN-?
Wei et al. (2011)IFNT-cellBy definition, a Th1 cell is a CD4+ T-cell that has the ability to respond to a specific antigen and produce the cytokines IFN?
Kezuka et al. (2011)IFNT cellsIn addition, the state of adhesion molecules expressed on antigen-presenting cells is a factor that attenuates inflammation. (3) Regarding the involvement of T cells and B cells, an increase in Th17-type T cells producing IFN-?
Worsley et al. (2010)IFNT-cellsmay be due to increased numbers of circulating T-cells that produce IFN-?
Karlsson et al. (2010)IFNT-lymphocytesIn six cases (Table 1), the expanded T-lymphocytes were functionally tested before transfusion by measuring the levels of the Th1 cytokine IFN-?
Shah et al. (2010)IFNT cellsAfter stimulating PBMCs for 4 hours with PMA and ionomycin, we identified CD4+ T cells producing IL-17, IFN-?
Shah et al. (2010)IFNT cellsWe next determined the ratio of CD4+ T cells producing IL-17 to the same cells producing IFN-?
Shim et al. (2010)IFNT cellsIt has been suggested that T cells producing IFN-?
Suwannasaen et al. (2010)IFNT cellsThese results indicated that bystander (both CD4+ and CD8+) T cells and NK cells could contribute equally to the production of IFN-?
Suwannasaen et al. (2010)IFNT cellsThese results demonstrated the similar characteristics of bystander T cells in producing IFN-?
Suwannasaen et al. (2010)IFNT cellIL-12-dependent pathway mediated T cell to produce IFN-?
Suwannasaen et al. (2010)IFNT cellsPreviously, proinflammatory cytokines such as IL-12, IL-15 and IL-18 have been reported to elicit bystander T cells to produce IFN-?
Suwannasaen et al. (2010)IFNT cellsThen, we highlighted the major finding that bystander CD4+ T and CD8+ T cells responding to dengue virus could account for approximately 50% of immune components producing IFN-?
Suwannasaen et al. (2010)IFNT cellsAdditionally, no synergistic action between IL-12 and IL-15 or IL-18 could be observed suggesting that the activation of T cells via IL-12 alone was sufficient to produce IFN-?.
Pohling et al. (2010)IFNT cellsin response to the HIV peptides were almost exclusively CD8+ as no increase over control values in the percentage of non-CD8+ T cells producing IFN-?
Pohling et al. (2010)IFNT cellSince the contribution of CD45RA+ naïve T cells to in vitro HIV-specific T cell responses is minimal, terminally differentiated HIV-specific CD8+ effector cells can be distinguished by co-expression of intracellular IFN-?
Pohling et al. (2010)IFNT cellsproducing cells for phenotypic analysis of HIV-specific CD8+ T cells by flow cytometry, we estimated the fraction of Ttd through CD45RA expression on HIV-specific CD8+ T cells producing IFN-?
Xu et al. (2010)IFNT cellsTo gain an insight into whether the adoptively transferred TILs could induce Th1 immune response which dominated antitumor immunity, ten days after transfer, the CD4+ T cells and CD8+ T cells were isolated from the tumor mass and analyzed for their production of IFN-?
Koido et al. (2010)IFNT cellsHSP70.PC from human fusions induced T cells that expressed higher levels of IFN-?
Eschenburg et al. (2010)IFNT cellsPAP is effective in inducing proliferating PAP-specific CD4+ and CD8+ T cells of the Th 1 isotype and expression of IFN-?
van der Windt et al. (2010)IFNT cellsWith regard to murine melioidosis it should be noted that natural killer cells, rather than T cells, are the main producers of IFN-?
van der Windt et al. (2010)IFNT-cellMoreover, T-cell dependent IL-12 production by human peripheral blood mononuclear cells is enhanced by OPN, in part via its ability to regulate CD3-induced expression of IFN-?
Nateghi Rostami et al. (2010)IFNT cellsIn another report the authors showed that after treatment of CL due to L. braziliensis, the frequency of CD4+ and CD8+ T cells was the same with approximately constant production of IFN-?
Nateghi Rostami et al. (2010)IFNT cellsResults of intracellular cytokine staining (ICS) in HCL volunteers confirmed that a significantly higher number of CD4+ T cells produced intracellular IFN-?
Nateghi Rostami et al. (2010)IFNT cellsTo confirm the real-time PCR results, part of CD4+/CD8+ sorted T cells were harvested following SLA stimulation and intracellular production of IFN-?
Nateghi Rostami et al. (2010)IFNT cellsIn mouse model of both genetically resistant and susceptible (that were rendered resistant) backgrounds, CD8+ T cells have been demonstrated to produce IFN-?
Nateghi Rostami et al. (2010)IFNT cellsThis proves the importance of CD8+ T cells as a source of IFN-?
Kim et al. (2010)IFNT cellNSAIDs were shown to inhibit T cell proliferation, expression of activation-related molecules such as CD25 and CD71, and the production of cytokines such as IL-2, IFN-?
Cong et al. (2010)IFNT cellsTransgenic mice immunized with the three single peptide lipopeptide vaccines had T cells that produced IFN-?
Vock et al. (2010)IFNT cellsRecently, a small subpopulation of skin-homing CD4+ T cells has been identified produced IL-22 as well but lack the production of IL-17 or IFN-?
Bergman and D'Elios (2010)IFNT cellUpon activation with the appropriate antigenic peptide, all H+K+-ATPase-reactive gastric T cell or H+K+-ATPase/H. pylori-cross-reactive T cell clones from AIG patients have a Th1 phenotype, characterized by production of IFN-?
Stempin et al. (2010)IFNT cellsModollel and colleagues demonstrated that arginase-1 is highly expressed at the site of pathology in nonhealing lesions and causes local depletion of L-arginine which impairs the capacity of T cells in the lesion to proliferate and to produce IFN-?
Koido et al. (2010)IFNT cellsNamely, HSP70.PCs derived from human DCs/tumor fusions induced T cells that expressed higher levels of IFN-?
Sarra and Monteleone (2010)IFNT cellsIn the MRL-Faslpr mouse, IL-21 is primarily made by an extrafollicular population of ICOS-expressing CD4+ T cells that exhibits reduced expression of P-selectin glycoprotein ligand 1 but is able to produce IL-4 and IFN-?
Heal and Taylor-Robinson (2010)IFNT cellsFollowing induction by IL-12, CD8+ T cells produce IFN-?
Yoshimoto et al. (2010)IFNT cellsThese results indicate that SLE T cells were “hyperactivated” by the stimulation in the production of IFN-?.
Yoshimoto et al. (2010)IFNT cellsAlthough the stimulation of the control T cells with the anti-CD3 antibody only slightly induced the expression of the IFN-?
Yoshimoto et al. (2010)IFNT cellsAs a response of T cells, we especially focused on the production of IFN-?
Yoshimoto et al. (2010)IFNT cellsStimulation of control and SLE T cells in vitro with an anti-CD3 antibody, an inducer of signal transduction through TCR, elicited the production of IFN-?
Yoshimoto et al. (2010)IFNT cellswas abnormally elevated in SLE T cells as compared with control T cells (Figure 1), as a consequence of the excessive expression of the IFN-?
Shafiani et al. (2010)IFNT cellsThese activated T cells produce protective cytokines, including IFN-?
Sasaki et al. (2010)IFNT cellsTumor-bearing host conditions also suppress the miR-17-92 cluster expression in T cells, which is associated with a loss in ability to produce IFN-?.
Kim et al. (2010)IFNT-cellsBoth CD4+ and CD8+ T-cells are known for their ability to produce high levels of IFN-?
Gregoriou et al. (2010)IFNT-cellsAdditionally, experiments in human alopecia areata by Deeths et al. show that antigen specific T-cells from patients with extensive disease appear to have some intrinsic defect towards production of IFN-?
Gregoriou et al. (2010)IFNT-cellsExperiments in mice have shown that BAFF may also activate T-cells and thus promote Th1 response, leading to the production of IFN-?
Pastore and Korkina (2010)IFNT cellIn particular, dermal myeloid DCs are increased in psoriatic lesions and induce T cell proliferation and the massive production of the type 1 cytokine interferon (IFN)-???
Park et al. (2010)IFNT cellsActivated T cells and NK cells produce IFN-?
Rynda et al. (2010)IFNT cells1 + anti-IL-28-dosed mice conferred protection against EAE (Figure 7B), upon peptide restimulation, their CD4+ T cells produced proinflammatory cytokines, IFN-?
Naeger et al. (2010)IFNT cellsSurprisingly, these responses were even higher among antiretroviral-treated individuals (on average, 6% of the peripheral CD8+ T cells from these subjects produced IFN-?
Fransen et al. (2010)IFNT cellsOverall these results show that after immunization of wild type mice with N. meningitidis OMVs, antigen-specific T cells mainly produce IFN-?.
Tapirdamaz et al. (2010)IFNT-cellsThe data revealed that there is a decrease in the proportions of recipient T-cells producing IFN-?
Becquart et al. (2010)IFNT cellsThe specificity of anti-ZEBOV IgG was confirmed by Western blot in 138 individuals, and CD8 T cells from seven IgG+ individuals were shown to produce IFN-?
Becquart et al. (2010)IFNT cellsWith samples from IgG+ individuals and from three survivors of ZEBOV infection, the percentage of circulating CD4+ T cells producing IFN-?
Becquart et al. (2010)IFNT cellsIn contrast, with samples from the seven IgG+ individuals, the percentage of circulating CD8+ T cells producing IFN-?
Loudon et al. (2010)IFNT cellSimilar to the CD4+ T cell response, immunization with the HA DNA vaccine alone elicited a HA-specific CD8+ T cell response in the blood that was comprised almost entirely of mono-functional T cells expressing either IFN-?
Loudon et al. (2010)IFNT cellsThe remaining population of HA-specific CD8+ T cells in the lungs of HA DNA vaccinated animals was made up of dual- and triple-cytokine expressing cells (13% and 5%, respectively), with the majority of dual-functional CD8+ T cells expressing IFN-?
Combadière et al. (2010)IFNT cellsMultiparametric flow cytometry assays were performed to determine the relative importance of the subpopulations of influenza-specific CD3+CD4+ and CD3+CD8+ T cells that produce IL-2, IFN-?
Olsen et al. (2010)IFNT cellsFor both of these vaccines, protection was found to be dependent upon CD4+ T cells producing IFN-?
Palma et al. (2010)IFNT cellsThird, XCL-1, a chemokine produced by activated CD8+ T cells during the chronic stage of MTB infection, which negatively affects production of IFN-?
Krummel et al. (2010)IFNT lymphocytesThe population of T lymphocytes responding rapidly with the production of IFN-?
García-Arriaza et al. (2010)IFNT-cellB16R induced a higher magnitude of HIV-1-specific CD4+ and CD8+ T-cell memory responses producing IFN-?
Hessel et al. (2010)IFNT-cellsWhen using the H1 CA/07 peptide pool for stimulation of the splenocytes, 1.3–1.4% of the CD4 T-cells produced IFN-?
Gu et al. (2010)IFNT cellsIn a representative experiment, of the CD4 T cells responding to the p24(65–73) peptide after one dose of the recombinant, 38% produced IL-2 alone, 40% produced IFN-?
Gu et al. (2010)IFNT cellsOf the CD8 T cells responding to the p24(65–73) peptide, 31% produced IL-2 alone, 37% produced IFN-?
Gu et al. (2010)IFNT cellsIn a representative experiment, of the CD4 T cells responding to the p24(10–30) peptide after two doses of the recombinant, 27% produced IL-2 alone, 41% produced IFN-?
Rajasekaran et al. (2010)IFNT cellsIn human T cells, NKG2D exclusively associates with DAP10 and not DAP12 and its co-stimulation enhances proliferation, survival, expression of activation markers and production of IFN-?
Diallo et al. (2010)IFNT cellsIn the acute uncomplicated malaria, it has been demonstrated that peripheral blood CD4+ T cells producing both IFN-?
Diallo et al. (2010)IFNT cellsMoreover, it has been shown that T cells from vaccinated healthy volunteers and adults naturally exposed to malaria with MSP1-19 could produce both IFN-?
Koh et al. (2010)IFNT cellswas prominent in CD4 T cells from wild-type mice while CD4 T cells from MyD88-deficient mice produced significantly less IFN-?.
Koh et al. (2010)IFNT cellsMyD88 is also important for the induction of a proper Th1 response during E. muris infection, as shown in both in vivo and ex vivo assays wherein CD4 T cells from MyD88-deficient mice produced less IFN-?
Valkenburg et al. (2010)IFNT cellsA high proportion of the wt DbNP366+CD8+ T cells in BAL (94.0% (10, d10); 93.2 (20, d8); Fig 2A) and spleen (69.8% (10, d10); 93.7% (20, d8); Fig 2B) bound the DbNPN3A tetramer and produced IFN-?
Schmidt et al. (2010)IFNT cellsrelative to BALB/c 2° memory CD8 T cells, the majority of which expressed IFN-?
Wilson et al. (2010)IFNT cellPhenotypically, tgd057-specific effector CTLs were generally representative of the total CD8+ T cell population and contained higher frequencies of cells expressing granzyme B and IFN-?
Cervantes-Barragan et al. (2010)IFNT cellsPeptide-specific CD8+ T cells and ex vivo production of IFN-?
Wagner et al. (2010)IFNT cellA third T cell population that simultaneously produces IFN-?
Yamano et al. (2009)IFNT cellsHowever, HAM/TSP patients show extremely high cellular and humoral immune responses such as high frequencies of Tax-specific CD8+ T cells as well as cytomegalovirus (CMV)-specific CD8+ T cells in PBMCs [7], [8], [28]; high antibody titer to HTLV-1 [6]; and increased production of proinflammatory cytokines such as IL-6, IL-12, and IFN-?
Yamano et al. (2009)IFNT cellT cell subset demonstrated that these cells were unique because they produce multiple proinflammatory cytokines such as IL-2, IL-17, and few IFN-?
Yamano et al. (2009)IFNT cellsCD4+CD25+ T cells from HAM/TSP patients also exhibit an activated phenotype marked by decreased expression of CD45RA together with increased expression of IFN-?
Yamano et al. (2009)IFNT cellsFurthermore, it has been demonstrated that HTLV-1-infected CD4+ T cells in HAM/TSP patients produce Th1 cytokines (IFN-?)
Yamano et al. (2009)IFNT cellsFurthermore, to examine whether these functional alterations in the CD4+CD25+CCR4+ T cells from HAM/TSP patients are specific to the cell subtype, we investigated the intracellular cytokine expression of IFN-?
Yamano et al. (2009)IFNT cellsHowever, it has been reported that HTLV-1-infected CD4+ T cells in HAM/TSP patients can produce IFN-?
Yamano et al. (2009)IFNT cellsCCR4-expressing CD4+ T cells include Th2, Th17, and Treg cells, and they do not tend to produce Th1 cytokines such as IFN-?
Yamano et al. (2009)IFNT cell, while this T cell subset produced low levels of IFN-?
Yamano et al. (2009)IFNT cellsHowever, it has been demonstrated that in HAM/TSP patients, HTLV-1-infected CD4+CD25+ T cells produce the Th1 cytokine IFN-?
Dao et al. (2009)IFNT cellsIt is possible that although D1-1 peptide could activate CD8 T cells to produce IFN-?
Boda et al. (2009)IFNT cellsT cells act as effectors either through cell-mediated cytotoxicity, following the release of dense cytoplasmic granules containing perforin and granzymes, or through the production of cytokines, including IFN-?
van de Wetering et al. (2009)IFNT cellsT cells produce IFN-?
Duffy et al. (2009)IFNT cellsIn mice immunised with Ag85B-ESAT-6 compared with BCG there were significant differences in the type of multifunctional T cells (i.e. those producing more than one of the cytokines IFN-?
Chen et al. (2009)IFNT cellsAlso, the addition of p286 peptide to the culture medium had no effects on either the proliferation of BDC2.5 T cells or the production of IL-10 and IFN??
Chen et al. (2009)IFNT cellsThese results showed that NR286 T cells significantly reduced the production of IFN??
Haghighi et al. (2009)IFNT cellsTo further examine the recognition of H5246–260 peptide by T cells, the expression of IFN-?
Clay et al. (2009)IFNT cellsFor example, T cells expressing ICOS at low levels produced IFN-?
Aagaard et al. (2009)IFNT cellsMoreover, the polyfunctional T cells in both the vaccine groups were more efficient producers of IFN-?
Aagaard et al. (2009)IFNT cells, it is interesting that on a per cell basis, the T cells from animals vaccinated with the low vaccine dose produced more IFN-?
Aagaard et al. (2009)IFNT cellsMoreover, the T cells from animals vaccinated with the low dose also produced more IFN-?
Caccamo et al. (2009)IFNT-cellFigure 4 shows peptide-specific CD8 T-cell producing single IFN-?