Viewing affirmative mentions of gene expression of CEL (H. sapiens) in T cells

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Fox et al. (2010)cellT cellGammadeltaTCR+ cells of the pregnant ovine uterus express variable T cell receptors and contain granulysin.
Zhang et al. (2010)cellT-cellAberrant expression of NK cell receptors in Epstein-Barr virus-positive gammadelta T-cell lymphoproliferative disorders.
Zhang et al. (2010)cellT-cellWe conclude that gammadelta T-cell expansion in EBV-positive gammadelta T-LPD is in part due to inappropriate expression of the NK cell receptors which related to impaired function cytotoxic T cells.
Taneja and David (2010)cellT-cellThe HLA transgene can positively select CD4(+) T cells expressing various V beta T-cell receptors, and a peripheral tolerance is maintained to transgenic HLA molecules.
Cognet et al. (2010)cellT cellsExpression of the HLA-C2-specific activating killer-cell Ig-like receptor KIR2DS1 on NK and T cells.
Hermann et al. (2010)cellT cellsKiller cell immunoglobulin-like receptor expression induction on neonatal CD8(+) T cells in vitro and following congenital infection with Trypanosoma cruzi.
Arun et al. (2010)cellT-cellBACKGROUND: Abnormal levels of T-cell antigen expression occur in T-cell neoplasia.
Gomyo et al. (2010)cellT cellTwo cases expressed aberrant T cell-associated antigens, one each of CD7 and CD8.
Malikhova et al. (2010)cellT-cellThe next important sign is coexpression T-cell marker CD43 on neoplastic B-cells.
Muramoto et al. (2010)cellT cellsE6201 also suppressed T cell receptor-stimulated IL-17 production from human T cells.
Ward et al. (2009)cellT cellECCM cultured cells also expressed lower levels of T cell co-stimulatory molecules, secreted an anti-inflammatory cytokine profile and had significantly reduced antigen-presenting capability.
Chen et al. (2009)cellT-cellSuch immune dysfunction may be due to reduced expression of the T-cell receptor (TCR) zeta chain, which is an important component in TCR-mediated signal transduction.
Zhou et al. (2009)cellT cellHerein, we investigated the effect of DNA demethylation on T cell CD40LG expression and the production of IgG by autologous B cells in lupus.
Zhou et al. (2009)cellT cellT cell CD40LG gene expression and the production of IgG by autologous B cells in systemic lupus erythematosus.
Gumbs et al. (2009)cellT-cellBACKGROUND: This disease process, also known as gamma/delta (gamma/delta) TCL because of the expression of the T-cell receptor gamma/delta chain, tends to present in young male patients.
Yu et al. (2009)cellT cellFinally, incubation of PBMC with these drugs reduced expression of IL-2 inducible T cell kinase (Itk), a Tec-family kinase, recently shown to be required for HIV-1 replication.
Gwak et al. (2009)cellT-cellMoreover, isoreserpine repressed the expression of beta-catenin/T-cell factor (TCF)-dependent genes, such as cyclin D1 and c-myc, resulting in the suppression of HCT116 cell proliferation.
Yu et al. (2009)cellT-cellGerminal-center T-helper-cell markers PD-1 and CXCL13 are both expressed by neoplastic cells in angioimmunoblastic T-cell lymphoma.
Muzzafar et al. (2009)cellT-cellThe frequencies of T-cell antigen expression in ALK(+) cases were CD2, 67%; CD7, 60%; CD3, 45%; CD4, 33%; CD5, 14%; and CD8, 14%.
Muzzafar et al. (2009)cellT-cellIn ALK(-) cases, the frequencies of the T-cell antigen expression were CD2, 100%; CD3, 50%; CD4, 40%; CD7, 40%; CD5, 25%; and CD8, 20%.
Wallentine et al. (2009)cellT-cellHowever, the expression of the lineage-specific T-cell antigen, CD3, in hematologic malignancies is exceedingly rare and to the best of our knowledge has not been reported in pediatric patients.
Fields et al. (2009)cellT-cellBiochemically, enzastaurin reduces expression of the PKCbetaII- and beta-catenin/T-cell factor-regulated genes PKCbetaII, cyclooxygenase II, and vascular endothelial growth factor, three genes implicated in colon carcinogenesis.
Wang et al. (2009)cellT cellsBACKGROUND: As one of the bacterial superantigens, Staphylococcal enterotoxins (SEs) are potent activators of T cells, especially for those expressing T cell receptor V(beta) chains, and can induce the production of cytokines such as IFN-gamma, TNF-alpha, IL-1, IL-2, IL-6, IL-12, etc.
Cornfield and Gheith (2009)cellT-cellIn addition, virtually no literature exists on the numbers and distribution of T lymphocytes expressing T-cell receptor alpha/beta (TCR alpha/beta) and T-cell receptor gamma/delta (TCR gamma/delta) in body effusions.
Tilburgs et al. (2009)cellT cellsExpression of NK cell receptors on decidual T cells in human pregnancy.
Tilburgs et al. (2009)cellT cellsThe aim of this study was to analyze expression of NK cell receptors on peripheral blood and decidual T cells during human pregnancy using flow cytometry.
Krishnamoorthy et al. (2009)cellT cellWe describe here the paradoxical development of spontaneous experimental autoimmune encephalomyelitis (EAE) in transgenic mice expressing a myelin oligodendrocyte glycoprotein (MOG)-specific T cell antigen receptor (TCR) in the absence of MOG.
Kim-Schulze and Kaufman (2009)cellT cellThus, we developed a recombinant vaccinia virus vector to express single or multiple T cell costimulatory molecules as a vector for local gene therapy in patients with malignant melanoma.
Hashimura et al. (2009)cellT cellSeveral studies have suggested that T cell-producing permeability factors might lead to proteinuria in minimal change nephrotic syndrome (MCNS).
Kronenberg and Kinjo (2009)cellT cellsInvariant natural killer T cells (iNKT cells) express a restricted T cell antigen receptor (TCR) repertoire and they respond rapidly to glycolipid antigens presented by CD1d.
Takatsuka et al. (2009)cellT-cellInduction of IL-10- and IFN-gamma-producing T-cell responses by autoreactive T-cells expressing human T-cell leukemia virus type I Tax.
Gassmann et al. (2009)cellT-cellIncreasing EMD concentrations resulted in dose-dependent enhanced T-cell CD25 receptor expression and in increasing apoptosis (P <0.001).
Yu et al. (2009)cellT cellsHere, we showed that Bcl-6 directs Tfh cell differentiation: Bcl-6-deficient T cells failed to develop into Tfh cells and could not sustain germinal center responses, whereas forced expression of Bcl-6 in CD4(+) T cells promoted expression of the hallmark Tfh cell molecules CXCR5, CXCR4, and PD-1.
Nakamura et al. (2009)cellT cellsThe killer cell lectin-like receptor G1, KLRG1, is a cell surface receptor expressed on subsets of natural killer (NK) cells and T cells.
Simonian et al. (2009)cellT cellIn a murine model of HP induced by exposure to the ubiquitous microorganism Bacillus subtilis, gammadelta T cells expressing the canonical Vgamma6/Vdelta1 T cell receptor were dramatically expanded in the lung.
Chiu et al. (2009)cellT-cellThe neoplastic lymphoid cells consistently expressed CD43 (seven of eight cases) and occasionally other T-cell-associated antigens, including CD5, CD7, CD8, and CD57.
Cheriyan et al. (2009)cellT-cellExpression of the T-cell signal transduction proteins, TCR-zeta, CD3-epsilon, zap-70, p(56)lck, PKC, NFkappabeta p50, Rel-A, Rel-B, and c-rel, was evaluated by using Western blot assay.
Sterclova et al. (2009)cellT-cellThe authors have found positive correlation between BALF CD4 T-cell CXCR3 expression and HRCT alveolar score in EAA patients (P <. 01).
White et al. (2008)cellT-cellIn the thymus, immature CD4+8+ thymocytes expressing randomly rearranged T-cell receptor alpha- and b-chain genes undergo positive and negative selection events based on their ability to recognize self-peptide/major histocompatibility complex (MHC) molecules expressed by thymic stromal cells.
Reinhold et al. (2008)cellT cellCombining inhibitors of DP IV and APN increases the suppressive effect on T cell specific IL-17 production in vitro compared to a single peptidase inhibitor.
Nozawa et al. (2008)cellT cellIn this study, we compared the expression of T cell receptor (TCR) V beta families in tonsillar T cells of IgAN patients to those of non-IgAN patients.
Wingender and Kronenberg (2008)cellT cellIn humans, populations of canonical NKT cells are found to be highly similar in terms of the expression of homologous, invariant T cell antigen-receptor alpha-chains, specificity, and function, although their frequency differs from those in the mouse.
Sela et al. (2008)cellT cellThus, hCDR1 down-regulates Akt phosphorylation, which leads to up-regulated expression of T cell Egr-2 and Egr-3, resulting in the inhibition of IFN-gamma secretion that is required for the maintenance of SLE.
Li et al. (2008)cellT cellThe alpha-galactosylceramide (alphaGalCer)-loaded CD1d tetramer remains the most powerful tool in identifying natural killer T (NKT) cells, a subpopulation of T cells that express an unusual semi-invariant T cell antigen receptor, and mediate a variety of proinflammatory and immunoregulatory functions.
Kabelitz (2008)cellT cellsThe major subpopulation of human peripheral blood gammadelta T cells expresses a Vgamma9Vdelta2 T cell receptor.
Hounoki et al. (2008)cellT-cellIn addition, both agonists inhibited the protein and gene expressions of nuclear factor of activated T-cell isoform c1 (NFATc1), c-Fos, c-Jun and NF-kappaB p65, which are known to be associated with osteoclastogenesis.
Rosenzweig et al. (2008)cellT cellMETHODS: Using intravital microscopy we examined the ocular inflammatory response after the onset of arthritis in mice that overexpressed the T cell receptor (TCR) specific for a dominant arthritogenic epitope of cartilage proteoglycan [TCR-Tg (transgenic) mice] or BALB/c controls.
Aizu et al. (2008)cellNFATHere we tested the hypothesis that CsA can modulate the expression of the nuclear factor of activated T-cell (NFAT) in epidermal keratinocytes.
Canivet et al. (2008)cellT-cellOur data suggest that, in mitogen-stimulated T-cells, (i) intra-lymphocyte cytokine expression is significantly higher in patients with liver disease than in healthy volunteers (n=25); (ii) the expression of T-cell activation markers is decreased in patients with liver cirrhosis compared to healthy volunteers, and (iii) the expression of T-cell activation markers and T-cell proliferation are increased in patients with HCV infection (n=15) compared to those without HCV infection (n=34), particularly compared to patients with alcoholic liver disease (n=19).
Streitz et al. (2008)cellT-cellReal-time RT-PCR of IFNgamma secretion-assay-enriched T-cells responding to the peptides, SALKLAIYKA and GLCPHCINVG, revealed a disproportionately high T-cell receptor Vbeta (TRBV) 11 expression in this population.
Olsnes et al. (2008)cellT cellIn vitro induction of a dendritic cell phenotype in primary human acute myelogenous leukemia (AML) blasts alters the chemokine release profile and increases the levels of T cell chemotactic CCL17 and CCL22.
Shimamura (2008)cellT cellA novel invariant Valpha19-Jalpha33 T cell receptor alpha chain, first found in mammalian blood cells, was primarily expressed by natural killer T cell repertoire (Valpha19 NKT cell).
Méhes et al. (2008)cellT-cellThe tumor cells express pan-B-cell markers and the T-cell marker CD5.
Prochorec-Sobieszek et al. (2008)cellT-cellAbnormalities of other T-cell antigen expressions (especially CD5, CD7, and CD43) were also detected.
Prochorec-Sobieszek et al. (2008)cellT-cellIn patients with polyclonal T-LGL lymphocytosis, T cells were dispersed in the bone marrow and the expression of pan-T-cell antigens in FCM was normal.
Foster et al. (2008)cellT-cellOne promising strategy consists of the genetic manipulation of effector T lymphocytes to express tumour-specific T-cell receptors or chimeric antigen receptors directed against surface antigens on the B-CLL cells.
Sharma et al. (2008)cellT-cellCONCLUSIONS: CD8+ T-cell CD127 expression is significantly higher in children with better HIV disease control, and may have a role as an immunologic indicator of disease status.
Caruso et al. (2007)cellT-cellA functional role for interleukin-21 in promoting the synthesis of the T-cell chemoattractant, MIP-3alpha, by gut epithelial cells.
Erbel et al. (2007)cellT-cellRESULTS: Carotid artery plaques from patients with ischemic symptoms compared to asymptomatic patients were characterized by the presence of high amount of T-cells (P<0.01) and tissue production of high levels of the T-cell cytokines IFN-gamma (P=0.001) and TNF-alpha (P=0.006).
Kenna et al. (2007)cellT cellCD1d-restricted natural killer T (NKT) cells expressing invariant Valpha14Jalpha18 T cell receptor alpha-chains are abundant in murine liver and are implicated in the control of malignancy, infection and autoimmunity.
Bueno et al. (2007)cellT cellSuch a feature is based on the ability of these toxins to activate T cells that express Beta-chains of the T cell antigen receptor (TCR) containing variable regions (V) coded by specific families of VBeta genes.
Wettstein et al. (2007)cellT cellsRepertoires of T cell receptors expressed by graft-infiltrating T cells evolve during long-term recall responses to single minor histocompatibility antigens.
Godlove et al. (2007)cellT cellsAt the gene expression level, one of the most striking changes is the altered expression of some co-stimulatory receptors and various NK cell receptors in CD28(-)CD8 T cells.
Cohen et al. (2007)cellT-cellEnhanced antitumor activity of T cells engineered to express T-cell receptors with a second disulfide bond.
Agnholt et al. (2007)cellT-cellIt was inversely correlated with in vitro T-cell IL-10 production.
Agnholt et al. (2007)cellT-cellOPN increased CD69 and CD25 expression and enhanced T-cell IFN-gamma and TNF-alpha production in a dose-dependent fashion with higher levels in CD than in healthy controls (HC), but induced a concomitant higher IL-10 production in HC than CD.
Kollnberger et al. (2007)cellT cellKIR3DL2 ligation by B27(2) inhibited NK and T cell IFN-gamma production.
Olson et al. (2007)cellT cellOur studies demonstrate that DIDOX inhibits T cell proliferation and the expression of the T cell activation molecules, CD25 and CD40L.
Yoshida et al. (2007)cellT-cellLikewise, a significant reduction in the development and growth of colorectal tumors was found in Villin-Cre Foxm1-/- mice compared with Foxm1 fl/fl mice after AOM/DSS treatment, which was associated with decreased expression of cyclin A2, cyclin B1, survivin, and T-cell factor 4 genes.
Weishaupt et al. (2007)cellT-cellCTL expressing T-cell receptors for the melanoma antigen MART-1 were identified in a subset of samples by reactivity with HLA-A2 tetramers loaded with MART-1 peptide.
Nakae et al. (2007)cellT cellHowever, although certain Th1-lineage markers [i.e., IL-18 receptor alpha, CXCR3, and T cell Ig domain, mucin-like domain-3 (TIM-3)], but not Th2-lineage markers (i.e., T1/ST2, TIM-1, and TIM-2), were expressed on Th17 cells, the intensity of expression was different between Th17 and Th1 cells.
Tsai et al. (2007)cellT-cellECs treated with IFNgamma induced the expression of three T-cell-specific CXC chemokines (CXCL9, CXCL10 and CXCL11) as well as CIITA, a transcriptional regulator of major histocompatibility complex class II (MHCII).
Bahlis et al. (2007)cellT-cellThe T-cell costimulatory receptor CD28 is also expressed on normal and malignant plasma cells, and CD28 expression in MM correlates significantly with poor prognosis and disease progression.
Goyos et al. (2007)cellT cellsThey may be involved in immune recognition of classical MHC class Ia (class Ia)-low or -negative tumor cells through their interaction with T cell receptors and/or non-T cell inhibitory or triggering receptors expressed by NK cells and T cells.
Solomou et al. (2007)cellT cellsThis study showed that T cells from patients with aplastic anaemia expressed decreased T-cell receptor (TCR) zeta-chain protein and mRNA levels compared to healthy controls.
Sullivan and Kronenberg (2007)cellT lymphocytesPopulations of unconventional T lymphocytes that express alpha beta T cell antigen receptors (TCRs) have been characterized, including T cells reactive to glycolipids presented by CD1 molecules.
Prescott et al. (2007)cellT-cellCONCLUSION: This is the first study to show that allergic disease is associated with altered expression of T-cell PKC isozymes in the neonatal period.
Hansson et al. (2007)cellT-cellSimultaneous nuclear expression of the transcription factor gene PAX5 suggested that this major driver of B-cell differentiation did not preclude expression of CD3epsilon, generally assumed to be a T-cell associated antigen.
Ballan et al. (2007)cellT cellsThis reduced function appears concurrently with distinct NK cell surface receptor expression and is associated with a loss of CD4+ T cells.
Turatti et al. (2007)cellT-cellNovel Ab-based immunotherapeutic strategies have exploited T-cell receptor-like chimeric immune receptors (CIR) expressed on the surface of transduced human peripheral blood mononuclear cell (PBMC) to redirect potent non-major histocompatibility complex-dependent cytotoxicity to tumor cells expressing a tumor-associated antigens.
Pedroza-Seres et al. (2007)cellT cellTo evaluate the phenotype and potential function of CD57+ T cell subsets CCR7, CD27, CD28, CD45RA, CD45RO, intracellular IFN-gamma, IL-4, perforin and granzyme-A expression were assessed by flow cytometry.
Atayar et al. (2007)cellT-cellsAIMS: To analyse the expression of the key regulatory T-cell transcription factors (TFs) in the T-cells of HL involved tissues in order to assess the nature of the T(H) immune response in HL.
Korematsu et al. (2007)cellT cellWhen the gammadelta T cell lines and mite-allergen-specific Th2 clones were co-cultured with each other, only the levels of IL-4 (mean, -87%) decreased, but not the levels of IL-5 and IL-13, with an increasing concentration of gammadelta T cell antigen and IFN-gamma production (mean, +730%).
Shondel et al. (2007)cellT-cellDifferential expression of T-cell CD3-zeta chains in patients with cervical dysplasia before and after treatment.
Eyerich et al. (2007)cellT cellNotably, Candida-specific T cell IL-10 production was markedly higher in CMC patients.
Chen et al. (2007)cellT lymphocytesInvariant natural killer T (iNKT) cells are innate T lymphocytes that express T cell receptors binding to exogenous and endogenous glycosphingolpid antigens presented by a nonpolymorphic, non-MHC antigen presenting molecule, CD1d.
Gupta et al. (2007)cellT-cellAberrant expression of T-cell antigens was found in all the cases of precursor T-cell neoplasm.
Orban et al. (2007)cellT cellsWe hypothesized that the function of human CD4+ T cells is altered in T1DM and analyzed unstimulated human peripheral blood CD4+ T-cell gene expression.
Chen and Kung (2007)cellT cellNKT cells, naïve CD4(+) T cells, and TCR-gammadelta T cells belong to distinct T cell lineages but all express T cell receptors generated through random combinatorial joining of V-(D)-J genes.
Krishnamoorthy et al. (2007)cellT cellMost recently, spontaneous autoimmunity resembling MS was obtained by transgenic expression of self-reactive T cell receptors and B cell receptors.
Lal et al. (2006)cellT cellIn the present study, we have shown that newly synthesized T cell receptor (TCR) beta chains formed as DRiPs in T cells are ubiquitinated and degraded by the proteasomes.
Chen et al. (2006)cellT-cellCo-cultured experiments revealed that TEC-related B7-H1 was identified as a strong inhibitor of CD4+ T-cell activation as assessed by increased cytokine production (interleukin-2 and interferon-gamma) and expression levels of the T cell activation marker (CD69) in the presence of a neutralizing antibody against B7-H1 (clone MIH1).
Ribeiro-Rodrigues et al. (2006)cellT cellExpansion of CD4+CD25+ regulatory T cells during active TB may play a role in depressed T cell IFN-gamma production.
Dupré et al. (2006)cellT cellsT cells harbored one or two vector copies and displayed partial to full correction of T cell receptor-driven interleukin-2 production and proliferation.
Eddahri et al. (2006)cellT cellMoreover, we show that CD4+ CD25+ T reg also suppress in vitro B cell immunoglobulin production by inhibiting CD4+ CD25- T cell help delivery, and that blockade of TGF-beta activity abolishes this suppression.
Krauss and Schuppan (2006)cellT-cellEleven patients (7.0%) with persisting (partial) villous atrophy were considered to have RCD; 5 of them developed EATL [27].RCD type I is characterized by normal expression of T-cell antigens and polyclonal TCR gene rearrangement.RCD type II is characterized by an abnormal IEL phenotype with the expression of intracytoplasmic CD3e, surface CD103, and the lack of classic surface T-cell markers such as CD8, CD4, and TCR-alpha/beta.
Rieux-Laucat et al. (2006)cellT cellsSome of the patient's T cells had low levels of the T-cell receptor-CD3 complex and carried the Q70X mutation in both alleles of CD3zeta, whereas other T cells had normal levels of the complex and bore the Q70X mutation on only one allele of CD3zeta, plus one of three heterozygous somatic mutations of CD3zeta on the other allele, allowing expression of poorly functional T-cell receptor-CD3 complexes.
Akyol et al. (2006)cellT-cellSera containing HSP10 suppressed T-cell CD3-zeta expression, which correlated with HSP10 levels (r2 = 0.839).
Kiyici et al. (2006)cellT cellRESULTS: The CD4/CD8 ratio was significantly decreased and expression of T cell receptor-gammadelta was increased in the infected group.
Nembrini et al. (2006)cellT cellHowever, the absence of any one of these factors during a weaker TCR signal, results in strikingly impaired T cell IFN-gamma production.