Viewing negative mentions of gene expression of CEL (H. sapiens) in T cells

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Dai et al. (2008)cellT cellTo test whether highly crossreactive alphabeta T cell receptors (TCRs) produced during limited negative selection best illustrate evolutionarily conserved interactions between TCR and major histocompatibility complex (MHC) molecules, we solved the structures of three TCRs bound to the same MHC II peptide (IAb-3K).
Kaleem et al. (2001)cellT-cellA control group of 59 cases of benign lymph nodes analyzed during the same period showed no aberrant expression of T-cell-associated antigens; thus, such expression is not a feature of benign lymphoid proliferations.
Katano et al. (1999)cellT-cellTY-1 exhibits indeterminate immunophenotype, expressing CD45 and CD30 cell surface antigens but not expressing B- or T-cell markers.
Bank et al. (1998)cellT cellsRESULTS: Flow cytometric and immunohistochemical analysis of the PBMCs revealed a major population (consisting of approximately 85% of the CD4+ T cells) that lacked expression of CD3 and T-cell receptors on the cell surface (CD4+CD3- T cells), but did express CD3 peptides in the cytoplasm.
Shikuwa et al. (1997)cellT-cellImmunohistological examination of these cells showed they were positive for epithelial membranous antigen (EMA), and neuron-specific enolase (NSE), but negative for UCHL1, leukocyte common antigen (LCA), anti-leukocyte B-cell (MB1), and anti-leukocyte T-cell (MT1) antigens.
Robertson et al. (1996)cellT cellNKL cells express CD2, CD6, CD11a, CD26, CD27, CD29, CD38, CD43, CD58, CD81, CD94, CD95, class II MHC, and the C1.7.1 antigen, but do not express detectable levels of CD3, CD4, CD5, CD8, CD14, CD19, CD20, CD28, alpha/beta or gamma/delta T cell receptors on the cell surface.
Schmidt et al. (1996)cellT cellsIn contrast to most CD4+ T cells, expanded clonotypes lacked the expression of the CD28 and CD7 cell surface molecules.
Chiang et al. (1996)cellT-cellAlthough they usually express a restricted number of T-cell-related antigens, namely, CD2, CD43, and CD45RO, other pan-T or subset-T-lineage antigens, such as CD3 (membrane), CD5, CD4, CD8, and CD7, are frequently absent.
Foss et al. (1996)cellT-cellHowever, both cytotoxic molecules and clonally rearranged T-cell receptor beta-chain genes were absent in seven of seven and eight of nine cases of B-cell ALCL (B-ALCL), respectively.
Shata et al. (1995)cellT cellAbsence of high-affinity binding sites for interferon alpha/beta in variant murine CD4+ T lymphocytes not expressing the T cell antigen receptor.
Sato et al. (1995)cellT-cellAlthough the majority of the tumor cells did not express T-cell related antigens, the detection of monoclonal TCR gene rearrangement clearly established the T-cell lineage nature.
Lima et al. (1994)cellT cellMembrane alpha beta and gamma delta T cell receptors (TCRs) were not expressed and the beta chain TCR gene was in germline configuration.
Clark et al. (1993)cellT-cellA-MuLV-transformed T-lymphoid cells did not express the CD3/T-cell receptor complex, while BCR-ABL tumors were CD3+.
Sawasdikosol et al. (1993)cellT cellThe rabbit lines were provisionally designated T cells because they express interleukin 2R (IL-2R) and CD5 and lack surface immunoglobulin, but none express functional T cell receptor (TCR) alpha or beta transcripts.
Groettrup et al. (1992)cellT cellTransfected T cell receptor (TCR) beta chain genes are expressed as homodimers on the surface of immature (Sci/ET27F) but not on mature (58 alpha-beta-) T cell lines which lack TCR alpha, gamma and delta chains.
Okumura et al. (1992)cellT cellDividing CD45RA-R0+ cells contain, therefore, many cells that have not yet expressed the CD3/T cell receptor complex and presumably have not yet undergone selective procedures.
Yoshiike et al. (1991)cellT cellsOn the other hand, activated T cell antigen (CD25+) was not significantly expressed on T cells (CD3+) in either HZ or PR.
Varga et al. (1990)cellT-cellIn all cases of LyP most larger cells expressed the activation antigen Ki-1 (CD30) and lacked expression of the T-cell antigen CD7 and at least one other T-cell antigen (CD2, CD3, CD5).
Stela et al. (1990)cellT-cellThe E receptors, the T-cell antigens, the HLA-DR antigens and smIgG were either expressed or not according to the affected organ, the progress of illness, or the treatment.
Mookerjee et al. (1989)cellT-cellThe proliferating cells predominantly expressed the T-cell antigens (CD3, CD4 and CD8), but not antigens of natural killer (NK) cells, B cells or mononuclear phagocytic cells.
Yssel et al. (1989)cellT cellThese cells did not express the CD3/T cell receptor complex on their surface.
Nguyen et al. (1989)cellT-cellThe five unclassified cases were cytochemically negative and expressed no B- or T-cell-specific antigens, or TdT positivity.
Aikawa et al. (1989)cellT cellsHowever, activated T cell antigen (Tac) was not significantly expressed on T cells (Leu-4+) in either HZ or in PR.
Jung et al. (1986)cellT cellsA T cell surface membrane-associated glycoprotein, Tp40 (40,000 mol wt), also designated as CD-7, was not expressed by the T cells of a patient with severe combined immunodeficiency.
Wieczorek et al. (1986)cellT-cellIn each case the large, pleomorphic neoplastic cells lacked the monoclonal antibody-defined cell surface antigens commonly associated with immature and mature T-cells, i.e., T11, Leu-1, T3, T4, T6, T8, and T10, but expressed various T-cell-associated activation antigens, such as HLA-DR, Tac, and T21.
Neudorf et al. (1984)cellT cellsWe found that T-cell-associated antigens were not expressed on Tdt+ bone marrow cells and that T cells in bone marrow have a phenotype similar if not identical to peripheral-blood T cells.
Doggett et al. (1984)cellT-cellLymphomas from 28 patients (31%) did not express immunoglobulin or T-cell antigens but commonly expressed the B-lineage antigen B1; and the remaining 9 cases generally expressed Ia antigens, common ALL antigens, or both.
Goto and Zvaifler (1983)NKT lymphocyteAMLR killer activity was virtually eliminated by treatment with C' and 9.6 or 4F2, but the cytotoxic cells did not express NK-specific antigens, OKM1 and Leu-7, nor cytolytic T lymphocyte-specific antigens, 9.3 and OKT8.
Palacios and Sugawara (1982)cellT-cellHydrocortisone abrogates proliferation of T cells in autologous mixed lymphocyte reaction by rendering the interleukin-2 Producer T cells unresponsive to interleukin-1 and unable to synthesize the T-cell growth factor.
Ferrara et al. (2006)cellT-cellOBJECTIVE: We have previously shown that mice lacking the tyrosine kinase inducible T-cell kinase (ITK) have drastically reduced airway inflammation in a model of allergic asthma.
Ling et al. (2004)cellT-cellUnlike that described in previous reports of SIV-related disease in SMs, the SIVsm infecting E041 was not first passaged through macaques; moreover, SM E041 was simian T-cell leukemia virus antibody negative.
Lamant et al. (2004)cellT-cellBoth large and small malignant cells were positive for CD43/MT1 T-cell associated antigen, perforin, granzyme B and TIA-1, but negative for CD2, CD3, CD5, CD7, CD4 and CD8 antigens.
Chikatsu et al. (2003)cellT-cellSouthern blot analyses revealed that Ig heavy and lambda light chain genes, but not T-cell receptor (TCR) beta gene, were clonally rearranged.
Tsuchiyama et al. (2002)cellT-cellAll three patients were negative for anti-adult T-cell leukemia antibody.
West et al. (2001)cellT-cellThis contraindication may not apply to newborn infants, who do not yet produce antibodies to T-cell-independent antigens, including the major blood-group antigens.
Little et al. (2001)cellT-cellIn response to IL-9, the HBE4-E6/E7 cell line, but not BEAS-2B cells, released the T-cell chemoattractants IL-16 and regulated on activation, normal T cells expressed and secreted (RANTES) in a dose-dependent fashion.
Krizanac-Bengez et al. (1998)cellT-cellSmall CD4+ cells, the majority of which are negative for other T-cell antigens during the first 2 weeks of culture, express low levels of CD4 (CD4lo) and coexpress granulocytic and/or monocytic markers.
Tsuchiyama et al. (1998)cellT-cellA Southern blotting using a terminal-repeat probe of EBV showed that NK-YS and fresh leukemic cells had a clonal EBV genome, whereas the T-cell receptor beta and gamma chain genes of NK-YS were not rearranged.
Eshima et al. (1996)cellT-cellBecause the T-cell receptor (TCR) alpha-chain locus is known to lack allelic exclusion of rearrangements, and as a recent report revealed the existence of alpha-chain double expressers among normal human peripheral blood lymphocytes (PBL), the possible existence of TCR alpha-chain double expressers among mature murine T cells was examined.
Brousset et al. (1996)cellT cellT cell receptor gamma chain genes were clonally rearranged in mycosis fungoides cells but not in RS cells, including variants, in both patients.
Shivdasani et al. (1995)cellT-cellAbsence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL.
Masuda et al. (1994)cellT cellPMT-2Y cells are positive for CD2, CD3, CD4, CD25, T cell receptor alpha beta and HLA-DR, but negative for CD1, CD7, CD8, CD19 and CD20, indicating that the clone belongs to a helper/inducer subset of T cells.
Kita et al. (1993)cellT-cellLeukemic cells from all the patients were negative for T-cell-specific antigens, surface CD3, and T-cell-receptor molecules.
Palacios and Samaridis (1992)cellT lymphocytesIndeed, both pro-B and pre-B clones can generate in vitro and in vivo B lymphocytes but not T lymphocytes; moreover, these clones do not express the CD3-gamma T-cell-specific gene, nor do they have rearranged gamma, delta, or beta T-cell antigen receptor genes.
Whetstone et al. (1992)cellT-cellWe used a BIV Western blot (immunoblot) analysis to examine human sera characterized as HIV-1 antibody positive, HIV-1 antibody negative, HIV-1 persistently indeterminate, HIV-1 p17 antibody positive only, HIV-1 p24 antibody positive only, human T-cell leukemia virus type 1 (HTLV-1) p19 antibody positive only, or HTLV-1 p24 antibody positive only.
O'Shea et al. (1992)cellT-cellThe effects of vanadate and hydrogen peroxide were enhanced in the absence of the T-cell PTPase, CD45.
Van Damme et al. (1992)cellT cellThe activity was not due to known T cell growth factors including human IL-9, which is not effective on mouse cells.
Chittal et al. (1991)cellT-cellReed-Sternberg cell and T-cell associated antigens were absent on large cells.
De Re et al. (1990)cellT-cellWith the exception of the MB2 B-cell-associated antigen, no B- and T-cell differentiation antigen was detected in case 1.
Krauss et al. (1989)cellT-cellSerologic tests were negative for human T-cell lymphotropic virus type 1 antibody.
Alfsen et al. (1989)cellT cellThe tumor cells carried the CD3 and CD7 T cell antigens, but were double negative for CD4 and CD8 and also lacked other T cell antigens (CD1, CD2, and CD5).
Moretta et al. (1987)cellT-cellThe last group of variants (lacking all the T-cell-specific surface antigens) only responded to calcium ionophore A23187.
Funke et al. (1987)cellT cellThe CD4+ cells were negative with anti-T cell antibodies (anti-CD2 and anti-CD8), as well as with antimonocyte antibodies (M-M 522 and M-M 42).
Mingari et al. (1987)cellT-cellSince previous studies indicated that PHA may be inefficient in inducing lymphokine production by T-cell variants lacking the CD3/T cell receptor complex (TCR), CD3- clones were further stimulated with the calcium ionophore A23187 plus phorbol 12-myristate 13-acetate (PMA).
Morishima et al. (1987)cellT cellA group of ALL cells whose cell surface phenotype was CD2 (SRBC receptor) negative and CD7 (T cell antigen) positive has been considered as precursor thymocyte ALL (pre-T-ALL).
Lanier et al. (1986)cellT cellHuman natural killer cells isolated from peripheral blood do not rearrange T cell antigen receptor beta chain genes.
Kitchingman et al. (1986)cellT cellAll cases met morphologic and cytochemical criteria for ALL, lacked detectable T cell surface antigens, and expressed HLA-DR (Ia) antigens.
Koide et al. (1986)cellT-cellAnti-T-cell antibodies were not essential for such immunoregulatory defects.
Koide et al. (1986)cellT-cellAnti-T-cell antibodies were not detected, and yet the patients had immunological abnormalities characterized by the presence of antinuclear antibodies and hypergammaglobulinaemia.
Barron et al. (1984)cellT cellAnti-T cell antibodies were found in 43/44 juvenile rheumatoid arthritis (JRA) patients (mean cytotoxicity 15.0%) and in 10/10 children with systemic lupus erythematosus (mean cytotoxicity 20.0%), but in only 1/15 normal controls and in none of 12 children with other arthritides.
Purtilo et al. (1983-1984)cellT cellHuman T cell leukemia virus-1 antibodies not detected in AIDS.
Buechner et al. (1983)cellT-cellThe absence of T-cell subset antigens in one patient with fulminant SÚzary syndrome and the finding of both T-cell subset antigens on T-cell leukemia cells suggest the presence of actively proliferating, immature T cells in those cases.
Haynes et al. (1981)cellT-cellThe antigen patterns of cutaneous T-cell lymphoma cells from peripheral blood and established cell lines were nearly identical; the cells were negative for human thymus antigen (OKT6 and NA1/34), positive for pan-T-cell (OKT3, 17F12, 10.2, and 9.6) and helper-T-cell-subset (OKT4) antigens, and negative for T-cell-subset antigens 3A1 and OKT8.
Strelkauskas et al. (1981)cellT cellThe Ig- cells from the subjects who had no detectable anti-T cell antibodies in their sera and near normal PFC levels were reactive with the JRA sera, whereas the Ig- cells from individuals with increased numbers of PFC and with serum anti-T cell antibodies were only slightly reactive with the JRA sera.
Su et al. (2010)cellT cellThese cells were negative for CD2, CD3, CD5, CD10, CD20, CD30, CD68, and T cell intracellular antigen (TIA).
de Souza et al. (2009)cellT-cellLesional T-cell receptor gene rearrangement studies were negative in 9 of 10 patients with LyP type A.
Schroers et al. (2005)cellT-cellComprehensive immunophenotypic analysis showed that the MCL cells expressed the typical B-lymphocytic markers, were CD5 and CD8 positive, but did not express other T-cell proteins, such as CD2, CD3, CD4, CD7, TCRalphabeta and TCRgammadelta.
Chadburn et al. (2004)cellT cellThe 8 KSHV-positive solid lymphomas were virtually indistinguishable from the 29 PELs based on morphology (immunoblastic/anaplastic), immunophenotype (CD45 positive; T cell antigen negative; CD30, EMA, CD138 positive; CD10, CD15, BCL6 negative) and genotype (100% immunoglobulin genes rearranged; no identifiable abnormalities in C-MYC, BCL6, BCL1, BCL2; and uniformly EBV positive).
Mikami et al. (2004)cellT-cellIn a polymerase chain reaction study of paraffin-embedded tissues, analyses for the rearrangement of immunoglobulin heavy chain and T-cell receptor-gamma genes were negative.
Spirito et al. (2003)cellT-cellThe leukemic cells did not express myelocytic or T-cell associated antigens and no molecular abnormalities were detected.
Leonard et al. (2001)cellT-cellThe malignant cells express pan B-cell markers, including CD19, CD20 and CD22, and the T-cell marker CD5, whereas CD10 and CD23 expression are usually absent.
Hara et al. (1997)cellT cellT cell receptor beta, T cell receptor gamma and immunoglobulin light chain rearrangement were negative.
Arnaud et al. (1997)cellT-cellT-cell antigen receptor (TCR) membrane-negative T-cell mutants can be divided into two groups: 1) those which lack one of the six TCR polypeptides and 2) those which contain a mutated TCR chain.
Sawabe et al. (1997)cellT-cellSerum anti-human T-cell leukemia virus type 1 and anti-human immunodeficiency virus were negative.
Zoubek et al. (1995)cellT-cellMoreover, the lymphoma contained a monoallelic D delta 2-D delta 3 T-cell receptor gene rearrangement which was also absent in the ET.
LeBoit et al. (1994)cellT-cellsThe neoplastic cells did not express the B-cell antigen CD20; T-cells formed the centers of many nodules.
Sneller et al. (1994)cellT cellA unique syndrome of immunodeficiency and autoimmunity associated with absent T cell CD2 expression.
Miller et al. (1992)cellT-lymphocyteThe cultured cells did not express other antigens associated with T-lymphocyte (CD3, CD5, T-cell receptor [TCR] alpha/beta and TCR gamma/delta), B-lymphocyte (CD19), myeloid (MY8, CD33, and CD71), or monocytoid (CD14 and CD15) lineage and did not express the CD34 antigen associated with hematopoietic progenitors present on the starting population.
Frank et al. (1990)cellT cellT cell hybridomas that express zeta zeta, but not zeta eta, dimers in their T cell receptors (TCRs) produce interleukin-2 (IL-2) and undergo an inhibition of spontaneous growth when activated by antigen, antibodies to the receptor, or antibodies to Thy-1.
Spencer et al. (1989)cellT cellIn normal human jejunum approximately 6% of the intraepithelial T cells expressing CD3 (an antigen associated with the T cell receptor) do not express the T cell subset antigens CD4 or CD8.
Geisler et al. (1989)cellT-cellFailure to synthesize the human T-cell CD3-zeta chain and its consequence for the T-cell receptor-CD3 complex expression.
Umadome et al. (1988)cellT cellIn the present study, we describe a case of chronic T-lymphocytic leukemia (T-CLL) with monoclonal proliferation of human T-lymphotropic retrovirus (HTLV)-I or HTLV-II negative CD3(+)4(+)8(-) T cell expressing IL-2 receptors without stimulation.
Miwa et al. (1987)cellT-cellInterestingly, most of the rearranged lines failed to express the T cell differentiation antigens, OKT 4 and 8, though their positive expression of Leu 1 antigen indicated the commitment to the T-cell lineage.
Duque et al. (1986)cellT-cellThe malignant cells in the skin and bone marrow were of the T4 (helper/inducer) phenotype, yet they did not express pan-T-cell antigens, such as T11, or functional E rosettes.
Tilden et al. (1983)cellT cellThis suppressor cell activity was predominantly mediated by a subset of HNK-1+ cells that have previously been shown to have maximum NK function and lack expression of the E rosette (ER) receptor and T cell antigens (e.g., T3 and T8).
Phillips et al. (1992)cellT lymphocytesUnlike T lymphocytes, NK cells do not rearrange or productively express T cell antigen receptor genes.
Ostrowski et al. (1999)cellT-cellImmunohistochemical stains revealed expression of CD15 and CD30 in neoplastic cells (which were negative for CD45 and B-cell and T-cell antigens) in all but two cases.
Landry et al. (1988)cellT-cellOn the other hand, thymic-cultured DC are negative for the other T-cell and monocyte-macrophage antigens.
Takeda and Okumura (2004)cellT-cellMoreover, in the innate immune system NK cells, which do not express T-cell receptors that recognize specific peptides presented on the major histocompatibility complex (MHC), rather than T cells, seem well suited for this role.