Viewing affirmative mentions of gene expression of IL2 (H. sapiens) in plasma

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Korting et al. (1993)IL-2plasmaUsing an interleukin-2 (IL-2)-dependent cell line it could be demonstrated that the addition of patients' plasma to cultured cells markedly depressed mitogen-induced IL-2 synthesis.
Farmer et al. (1986)interleukin 2plasmaInhibition of interleukin 2 production and expression of the interleukin 2 receptor by plasma from acquired immune deficiency syndrome patients.
Clerici et al. (1997)IL-2plasmaPentoxifylline also potentiated antigen-stimulated IL-2 production and proliferation in 8 of 9 patients and induced significant but transient decreases in plasma viremia in 7 of 9 patients.
Ide et al. (1989)IL-2plasmaIn addition to the assay of mitogenic response (PHA), we measured IL-2 production and response utilizing IL-2 dependent cytotoxic T cell line and mitogenic proliferation to standard IL-2 respectively concomitant with plasma cortisol level.
Tu et al. (1995)IL-2plasmaDifferences found between in vivo aging and in vitro incubation are IL-2 plasma levels and IL-2 production by activated cells monitored in conditioned minimal medium.
Szamel et al. (1989)IL-2plasmaIncorporation of polyunsaturated fatty acids into plasma membrane phospholipids regulates IL-2 synthesis via sustained activation of protein kinase C.
Jacobson et al. (1996)IL-2plasmaIL-2 was already detectable in the plasma of most HIV+ individuals even before therapy.
Rey et al. (1984)IL-2plasmaConversely it is demonstrated that patient plasma contain immunosuppressive factor(s) that block(s) IL-2 production and ARF cell expression.
Kluge et al. (2009)interleukin-2plasmaBody mass index (BMI), tympanic temperature, and plasma levels of leptin and cytokines (tumor necrosis factor-alpha (TNF-alpha), soluble TNF receptor 1 and 2 (sTNFR-1/2), soluble interleukin-2 receptors (sIL-2R), interleukin-6) were determined weekly.
Hodge et al. (2005)IL-2LDPIn cell cultures exposed to poststorage LDP, T-cells showed reduced expression of CD69, CD25 (IL-2Ralpha), CD122 (IL-2Rbeta) and CD132 (IL-2Rtau) and production of TNF-alpha and IL-2 but there was no significant alteration for IFN-tau or IL-4.
Licastro et al. (1994)interleukin-2plasmaAlong with plasma levels of zinc, the immune parameters, measured before and after zinc treatment, were plasma levels of thymulin, the percentage and the absolute number of circulating white blood cells, total lymphocytes, lymphocyte subpopulations, the mitogen-induced lymphocyte proliferation, the production of interleukin-2, and the activity of stimulated granulocytes.
Wester et al. (1998)IL-2plasmaThe human plasma protein alpha1-microglobulin (alpha1m) was found to inhibit the antigen-induced interleukin-2 (IL-2) production of two different mouse T-helper cell hybridomas.
Szamel et al. (1995)IL-2plasmaThey implicate that elevated incorporation of polyunsaturated fatty acids into plasma membrane phospholipids might contribute to sustained activation of protein kinase C-beta, and establish a link between activation of protein kinase C-beta and induction of IL-2 synthesis in human lymphocytes.
Robins et al. (1991)Interleukin 2plasmaInterleukin 2 was detected in the plasma of four of six patients after 105AD7 immunization, with peak levels up to 7 units/ml.
Schiphorst et al. (1999)IL-2plasmaCONCLUSIONS: IL-2 plasma half-life is only moderately prolonged in anephric patients as compared to patients with normal renal function.
Tedaldi et al. (2005)IL-2plasmaWe measured the impact of IL-2 on plasma HCV RNA levels in 54 human immunodeficiency virus (HIV)/HCV coinfected patients enrolled in a randomized trial of 512 participants designed to compare the virologic and immunologic effects of cycled IL-2 plus antiretroviral therapy (ART) vs ART alone in the treatment of HIV in patients with CD4 cell counts > or =300 cells/mm(3).
Jacobson et al. (1996)IL-2plasmaPeak plasma IL-2 levels were near saturating for high affinity IL-2 receptors in 10 individuals who received the maximum nontoxic dose, which ranged from 187,500 to 250,000 IU/m2/day.
Allegra et al. (1998)IL-2plasmaPatients with detectable IL-2 plasma levels had significantly lower plasma T(3) and FT(3) concentrations when compared to those with undetectable IL-2.
He et al. (2004)interleukin-2plasmaThe membrane fluidity, interleukin-2 (IL-2) production and interleukin-2 receptor (IL-2R) expression in PBMCs and malondialdehyde (MDA) concentration in medium and lipid peroxide (LPO) in plasma were determined.
Clendenen et al. (2010)IL-2plasmaSix markers met our a priori criteria, ie detectable in over 40% of samples and ICC threshold of 0.55, in the present study of EDTA plasma that did not make this cutoff in the serum reliability study: sIL-6R (ICC = 0.52 in the serum study), and sIL-2R, IL-15, hsIFN?
Galhardo et al. (2001)IL-2plasmaPATIENTS AND METHODS: Tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), soluble IL-2 receptors (sIL-2R), beta2-microglobulin serum levels and plasma viral load of 45 HIV-positive patients were determined and correlated to nutritional status impairment.
Saberi Hosnijeh et al. (2010)IL2plasmaCONCLUSIONS: The results of this study suggest, in a prospective setting, a possible association between plasma levels of IL2, ICAM, IFN-gamma, and TNF-alpha with NHL risk and provide some evidence that risk of NHL might be related to a downregulation of T helper 1 cytokines.
Cutando et al. (2003)IL-2plasmaThus, we compared the degree of PD and interleukin-2 (IL-2) levels with melatonin concentrations in plasma and saliva of diabetic patients.
Anisman et al. (1999)IL-2plasmaMoreover, IL-2 production in the depressive groups was directly related to plasma NE levels.
Bruunsgaard et al. (2000)IL-2plasmaThe aim of the study was to investigate if plasma levels of tumor necrosis factor (TNF)-alpha were associated with leptin, circulating interleukin-2 receptors (sIL-2R), and phytohaemagglutinin (PHA) induced IL-2 production in whole blood in elderly humans.
Tyler et al. (1986)IL-2-dependentplasmaNeither toxicity nor inhibition of the IL-2 response was observed when the IL-2-dependent indicator cells were preincubated in post-DST+A plasma prior to an IL-2 dose-response assay.
Citterio et al. (1996)IL-2plasmaFor each cycle, plasma samples were collected before treatment (t0), 24 h (t1), 48 h (t2), 72 h (t3) and 96 h (t4) after the start of IL-2 infusion, and 24 h after the end of the cycle.
Guidi et al. (1999)IL-2plasmaWe detected modifications of some psychological test scores between the Baseline and Stress evaluation, a significant reduction of lymphocyte proliferation, IL-2 production and percentage of the lymphocyte CD19, and an increase in plasma cortisol levels during stress.
Havas et al. (1993)interleukin-2plasmaMBV's effect on interleukin-2 (IL-2) production, plasma interferon (IFN) and tumor necrosis factor (TNF) levels was monitored.
Sadeghi et al. (2007)IL-2plasmaViral Load (VL), CD4+ lymphocyte counts, and plasma levels of sIL-1RA, IL-2, sIL-2R, IL-3, IL-4, IL-6, sIL-6R, IL-7, IL-10, TNF-alpha, TGF-beta2, IFN-gamma, and sCD30 were measured in 18 patients who received HAART.
Curry et al. (2007)interleukin 2plasmaMid-pregnancy maternal plasma levels of interleukin 2, 6, and 12, tumor necrosis factor-alpha, interferon-gamma, and granulocyte-macrophage colony-stimulating factor and spontaneous preterm delivery.
Neri Serneri et al. (2003)IL-2PlasmaPlasma levels of IL-2 soluble receptor (sIL-2R) were measured as a marker of systemic immune reaction.
Muñoz et al. (2005)IL-2plasmaRESULTS: After supplementation, a significant increase in IL-2 production was found only in subjects with normal-low plasma Cp.
Meydani et al. (1990)IL-2plasmaIn the vitamin E-supplemented group 1) alpha-tocopherol content was significantly higher (p less than 0.0001) in plasma and PBMCs, 2) cumulative diameter and number of positive antigen responses in DTH response were elevated (p less than 0.05), 3) IL-2 production and mitogenic response to optimal doses of concanavalin A were increased (p less than 0.05), and 4) PGE2 synthesis by PBMCs (p less than 0.005) and plasma lipid peroxides (p less than 0.001) were reduced.
Allegra et al. (1998)interleukin-2PlasmaPlasma interleukin-2 levels and thyroid function in elderly patients with nonthyroidal illness.
Hamon et al. (1993)IL2plasmaStudies of peripheral blood lymphocytes (PBL) and plasma from patients with malignant lymphoma [Hodgkin's disease (HD) and non Hodgkin's lymphoma (NHL)] show that plasma soluble interleukin 2 receptor (sIL2R) levels are closely linked with disease status [normal volunteers (n = 15) 402 +/- 158 u/ml; patients with Hodgkin's disease in remission (n = 4) 525 +/- 195 u/ml or with active disease (n = 11) 3026 +/- 1602 u/ml (p < 0.001); patients with non Hodgkin's lymphoma in remission (n = 6) 462 +/- 202 u/ml, active disease (n = 15) 2713 +/- 1755 u/ml, (p < 0.001)] but no correlation between sIL2R and the inhibition of interleukin 2 (IL2) generated cytotoxicity for the cell line K562.
Hamon et al. (1993)interleukin 2PlasmaPlasma soluble interleukin 2 receptor levels in patients with malignant lymphoma are correlated with disease activity but not cellular immunosuppression.
Kwak et al. (2002)IL-2PlasmaPlasma IL-2 concentration and in vitro production did not change throughout the study, although five of seven subjects showed increases with intakes of 2.1 and 2.7 mg B-6/d, respectively, compared with the 1.5 mg/d intake.
Gupta et al. (1991)IL-2plasmaBoth antibodies depolarized plasma membranes, increased cell volume, induced IL-2 production and the expression of IL-2 receptors (CD25 antigen) and induced DNA synthesis.
Arankalle et al. (2010)IL2plasmaThe disease severity correlated with increased plasma levels of IL1RA, IL2, IL6, CCL3, CCL4 and IL10.
de Gruijl et al. (1999)IL-2plasmaT-helper (Th) cell-dependent IL-2 production and plasma IgG responses to virus-like particles consisting of the human papillomavirus type 16 (HPV-16) major capsid protein L1 (L1-VLP) were determined in patients with cytological evidence of cervical intraepithelial neoplasia (CIN) participating in a non-intervention prospective cohort study.
Engel et al. (2009)IL-2plasmaThe elevation of glutamine plasma levels by a perioperative intravenous infusion of L-alanyl-L-glutamine influenced the intracellular expression of IL-2 in the lower tertile only slightly.
Craddock et al. (2007)IL-2plasmaLower numbers of CD4+ cells and hence IL-2 production have also been reported in schizophrenia [15], although Muller et al describe increased CD4+ cell number [16], in addition to altered plasma and serum levels of other cytokines such as IL-6 [17].
Moldawer et al. (1988)IL-2plasmaTo evaluate their potential role, food intake and liver and plasma protein synthesis were determined in both endotoxin-sensitive C57Bl/6j mice and endotoxin-resistant C3H/HeJ mice given either crude secretory products of Staphylococcus albus-stimulated human blood monocytes or murine recombinant IL-1-alpha, human recombinant IL-1-alpha or -beta, human recombinant tumor necrosis factor-alpha, or human IL-2.
De Luca et al. (2000)IL-2plasmaPatients with late-stage HIV infection (CD4+ cells <50/microl) showed a higher production of MIP-1alpha and RANTES and lower plasma levels of IL-2 compared with HIV-positive patients at the intermediate stage (CD4+ cells >150/microl).
Mocchegiani et al. (1999)IL-2plasmaThey showed reduced active thymulin, decreased NK activity and IL-2 production, increased soluble IL-2 receptor (sIL-2R) and augmented alpha2-macroglobulin in the circulation, whereas plasma zinc levels were within the normal range for age.
Alpsoy et al. (1998)interleukin-2RplasmaThe levels of plasma interleukin-2 and soluble interleukin-2R in Behçet's disease: a marker of disease activity.
Salazar et al. (2010)IL-2PlasmaPlasma levels of IL-2, IL-10, IL-12, IL-17, and TGF-b were determined using commercially available kits purchased from Genzyme and R & D systems (Quantikine) carefully following the manufacturer instructions.
Peng et al. (2010)IL-2plasmaThe blood samples were taken to measure the changes of plasma cytokines (IFN-gamma, TNF-alpha, IL-1, IL-2, IL-4, IL-6, IL-10 and IL-13) and HLA-DR expression on monocytes.
Peng et al. (2010)IL-2plasmaAfter CVVH treatment, the plasma levels of IFN-gamma, IL-1, IL-2, IL-4, IL-10 and IL-13 in septic patients were markedly decreased (P<0.05), while the levels of TNF-alpha and IL-6 were only lowered to some extent without significant difference (P>0.05).
Mier et al. (1990)IL-2-inducedplasmaTo determine if dexamethasone can exert a similar suppressive effect on IL-2-induced TNF synthesis in vivo, the concentration of TNF alpha was measured in plasma samples serially obtained (a) from cancer patients participating in a phase I dose escalation clinical trial with high-dose IL-2 administered in conjunction with dexamethasone (IL-2/Dex) and (b) from patients participating in concurrent studies with IL-2 alone.
Chi et al. (2001)IL-2plasmaSerial plasma level of TNF-alpha, IL-6, soluble IL-2 receptor, IL-10 and soluble CD8 were determined.
Amicosante et al. (2003)IL-2plasmaNo differences were observed in levels of IL-2, IL-7, or interferon-alpha in plasma.
Arankalle et al. (2010)IL2plasmaWe identified higher plasma levels of IL1RA, IL2, IL6, CCL3, CCL4 and IL10 as markers of severity.
Enk et al. (1986)interleukin-2plasmaThe three patients with reduced interleukin-2 production and low proliferative responses were exclusively characterized by elevated plasma-IgG concentration, positive antinuclear antibodies and rheumatoid factor, and by having circulating immune complexes.
Wiedermann et al. (2001)interleukin-2plasmaWe measured plasma levels of endotoxin and serum levels of neopterin and soluble interleukin-2 receptor in a random population of 402 men and women, 50-79 years old at the 1990 baseline evaluation (Bruneck Study).
D'Armiento et al. (2009)IL-2plasmaRESULTS AND DISCUSSION: Stable COPD participants had significantly higher plasma IL-2 levels compared to participants with rapidly progressive COPD (p = 0.04).
van Haelst Pisani et al. (1991)IL-2plasmaAdministration of interleukin-2 (IL-2) results in increased plasma concentrations of IL-5 and eosinophilia in patients with cancer.
Citarella et al. (1997)IL-2plasmaMoreover, we show that, in patients developing an acute-phase response after immunotherapy with IL-2, plasma levels of factor XII correlate (r = .76, P < .0001) with those of transthyretin.
Abdulhamid et al. (2008)IL-2PlasmaPlasma Zn, Cu, inflammatory cytokines and ex vivo generation of IL-2 were measured at baseline and at the end of the study.
Hauser et al. (1997)IL-2plasmaTNF-alpha, IL-1 beta, IL-2, and interferon-gamma were rarely found in FxSTH serum or fracture patient plasma.
Blish et al. (2010)IL-2plasmaAlbendazole treatment, compared with placebo, was associated with significantly decreased plasma interleukin (IL) 10 levels (P = .01)ot associated with significant changes in levels of IL-1beta, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-12p70, IL-13, interferon gamma, tumor necrosis factor alpha, or thymic stromal lymphopoietin.
Wissing et al. (1997)IL-2plasmaThere was also a trend toward reduced plasma levels of IL-2, IL-8, and interferon-gamma in rhIL-10-pretreated patients.
Chibowska et al. (2001)IL-2plasmaPentoxyfilline treatment does not influence the plasma levels of IL-2 and sIL-2R in limited scleroderma patients.
Chibowska et al. (2001)IL-2PlasmaMATERIAL AND METHODS: Plasma levels of IL-2 and sIL-2R were measured by ELISA in 23 patients with limited scleroderma (1SSc-acrosclerosis) and compared with 12 healthy women.
Chibowska et al. (2001)IL-2plasmaTreatment with pentoxyfilline did not influence the plasma levels of IL-2 and sIL-2R.
Chibowska et al. (2001)IL-2plasmaCONCLUSIONS: We concluded that elevated plasma levels of IL-2 and sIL-2R are markers of internal organ involvement in scleroderma.
Kim et al. (2000)IL-2plasmaIL-1beta, IL-2, IL-6, homovanillic acid (HVA), and 5-hydroxyindoleacetic acid (5-HIAA) were measured in the plasma of neuroleptic-free male schizophrenics in comparison to age-matched healthy male controls (n=25 each).
Ostrowski et al. (2006)IL-2plasmaIn addition, plasma levels of the following inflammatory markers were also investigated: soluble tumour necrosis factor receptor (sTNFr)-II, TNF-alpha, interleukins (IL)-10, IL-6, IL-4, IL-2 and interferon (IFN)-gamma.
Angelini et al. (1994)interleukin 2plasmaIn the present study we examined the relationship between plasma levels of PTH, interleukin 2 receptors (IL-2R) and soluble human CD8 (S-CD8).
Kim et al. (2000)IL-2plasmaThe plasma levels of IL-2 and HVA were significantly higher in patients compared to controls.
Kim et al. (2000)IL-2plasmaIn schizophrenic patients, the plasma levels of IL-2 and HVA were significantly lowered after treatment with haloperidol.
Baker et al. (1989)IL-2plasmaThey noted an increased synthesis of total "biopterins," i.e., biopterin; 7,8-dehydrobiopterin; and L-neopterin in LAK cells and plasma which correlated with IL-2 exposure.
Fong et al. (1994)IL-2PlasmaPlasma IL-1 and IL-2 levels were higher in Group 1 [IL-1 alpha: 408 pg/ml (SEM: 107), IL-2: 4.20 ng/ml (SEM: 1.5)] than in Group 2 [IL-1 alpha 150 pg/ml (SEM: 15), IL-2: 2.58 ng/ml (SEM: 0.7)] or Group 3 [IL-1 alpha: 140 pg/ml (SEM: 11), IL-2: 1.93 ng/ml (SEM: 0.3)] (p < 0.01, p < 0.009 respectively).
Harada et al. (2005)IL-2plasmaMNCs were cultured for 12 days in AIM-V medium containing alpha-galactosylceramide (alpha-GalCer) (100 ng/mL) and IL-2 (100 U/mL) supplemented with FBS, autologous plasma, or autologous serum.
Zhang et al. (1995)IL-2plasmaOn day 6 after induction of 11%-12% TBSA full-thickness burn, the animals were sacrificed, and proliferation and IL-2 production of splenic lymphocytes, LPO levels of the plasma, livers and spleens were measured.
Miao et al. (1996)IL-2HSPIn addition, the HSP and PGE2 treatment used inhibited the production of the Th1 cytokines IL-2 and IFNg but had a differential modulatory effect on Th2 cytokine production, namely enhancing the production of IL-6 whilst simultaneously impairing the synthesis of IL-4 and IL-10.
Moldawer et al. (1992)interleukin-2plasmaElevated plasma levels of tumor necrosis factor-alpha, interleukin-2, and interferon-gamma have rarely been detected in patients or experimental animals with cancer, although interleukin-6 levels appear to correlate with tumor progression in animal models.
Saglam et al. (2009)IL-2PlasmaPlasma TNF-alpha and IL-2 levels were positively correlated in ERBB2+ breast cancer patients (p<0.01).
Hsu et al. (2003)interleukin-2plasmaThe plasma levels of interleukin-2 (IL-2), tumor necrosis factor-alpha (TNF-alpha), ICAM-1, P-selectin, high-sensitive C-reactive protein (CRP) and troponin-I of CS and PB were determined.
Tripathy et al. (2006)IL-2plasmaWe have investigated intracellular production by T cells and plasma levels of TNF-alpha, IL-2 and IFN-gamma in 12 active and 10 inactive Takayasu's arteritis (TA) patients and 12 healthy controls.
Tilg et al. (1993)IL-2plasmaIL-8 was detectable in the plasma within 2-4 h after the first IL-2 infusion, reached a peak level after 4 h, and declined rapidly to undetectable within 8 h.
Kassu et al. (2009)IL-2plasmaSuppression of viral replication with antiretroviral therapy was associated with increased 4-1BB expression on HIV- and CMV-specific IL-2 producing CD4+ T cells (P<0.05 and P<0.01, respectively) and the percentage of IL-2 producing HIV-specific CD4+ T cells that expressed 4-1BB was inversely correlated with HIV plasma viral load (r=-0.75, P=0.007).
Matalliotakis et al. (1998)IL-2plasmaOur results show that the mean IL-2 and sCD4 concentrations in the seminal plasma were significantly higher compared to the levels in the serum of normal men; furthermore, there were no significant differences of SIL-2R and sCD4 between the group of normal men and the groups of men with oligozoospermia or azoospermia.
Fletcher et al. (2009)IL-2plasmaMedian plasma levels of IL-2 and IFN?