Viewing negative mentions of gene expression of IL2 (H. sapiens) in NK cells

Full-text article links are indicated by after the article reference.

Document Target Regulator Anatomy Sentence
Pistoia et al. (1986)IL-2LGLLGL proliferated in response to rIL-2 but did not express detectable IL-2 receptors, even after prolonged periods of culture.
Vitolo et al. (1993)IL-2Rp55NK cellsThus, the genes for the IL-2Rp55 and these cytokines were not constitutively expressed by most human R-NK cells, and there was no indication that the NK cells used in these experiments were activated in vivo or during the purification procedure.
Nakamura et al. (1989)interleukin 2natural killer cellA large number of interleukin 2 receptors lacking the Tac epitope (IL-2R/p75) were found to be constitutively expressed on the human large granular lymphocyte/natural killer cell line YT, which bears inducible IL-2R/p55 associated with Tac antigen.
Hayakawa et al. (1991)IL-2NK cellsIL-2 was not detected in the supernatant from IL4d-NK cells, nor was IL-2-mRNA expressed in IL4d-NK cells.
Rambaldi et al. (1986)IL-2LGLIn the absence of stimulation, the patients' LGL produced no IL-2 and only minimal amounts of IL-1 and interferon (IFN).
Keever et al. (1990)IL2NK cellsIL2 receptor (CD25) expression was low in all cultures but was consistently higher in cultures containing IL1 and IL2, however, CD25 was not coexpressed on NK cells.
Bishop et al. (1987)interleukin 2NK cellsHowever, the enhanced lytic activity of NK cells following exposure to low doses of infected cell cold targets cannot be explained solely on the basis of release of the three lymphokines tested, since interleukin 1 was not effective, interleukin 2 was not detected in culture supernatants derived from the competition experiments, and NK cells preferentially lyse HSV-1-infected target cells independent of the enhancing effects of interferon.
Shabsoug et al. (2008)IL-2NK cellLastly, in the absence of IL-2, plant extracts caused a significant increase in NK-cell-induced cytotoxicity (256%) against K562 tumor cells, and in the presence of IL-2 stimulated cells plant extracts caused an increase in NK cell-cytotoxicity (112%).
Baume et al. (1992)IL 2NK cellsUnlike CD56bright cells, CD56dim NK cells do not proliferate optimally to IL 2, even after the latter have been stimulated to express both IL 2R p55 and IL 2R p75.
Morris et al. (2006)IL-2large granular lymphocyteThis latter observation may reflect the fact that the monoclonal T cell large granular lymphocyte leukemia leukemic cells of the patients did not produce IL-2 or IL-15 or require their actions for cell survival.
Rabinowich et al. (1992)IL-2NK cellsNumerous lymphoid cells expressing cytokine or IL-2R genes were observed in these tumors, whereas the cultured IL-2-activated NK cells used for therapy were negative.
Mani et al. (2009)IL-2NK cellIn trastuzumab-refractory patients adding IL-2 did not produce responses and did not result in NK cell expansion.
Carson et al. (1997)IL-2 geneNK cellsMice that lack the IL-2 gene have NK cells, whereas mice and humans that lack IL-2R gamma(c) do not have NK cells.
Yamada et al. (1987)interleukin 2LGLWe were unable to detect interleukin 2 receptors (IL 2R) on fresh LGL and T cells using flow cytometric analysis with anti-Tac monoclonal antibody or radiolabeled probes with [125I]anti-Tac.
Loughran et al. (1987)IL 2LGLDespite induction with anti-CD3 MAb or IL 2, activated leukemic LGL did not proliferate or express high density IL 2 receptors detectable by cell sorter analysis.
Vitale et al. (2004)IL-2NK cellsSuch cultured NK cells also failed to express the IL-2-inducible NKp44 receptor.
Pistoia et al. (1986)interleukin-2-dependentlarge granular lymphocytesEstablishment of Tac-negative, interleukin-2-dependent cytotoxic cell lines from large granular lymphocytes (LGL) of patients with expanded LGL populations.