Viewing affirmative mentions of gene expression of IL2 (H. sapiens) in lymph node

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Viselli and Mastro (1989)IL-2lymph nodeWhen bovine lymph node cells (bLNC) were stimulated with the combination of concanavalin A (ConA) and 12-O-tetradecanoylphorbol-13-acetate (TPA) for 24 h, 46.4 +/- 0.6% stained positive for IL-2 and, on average, each cell produced 0.92 +/- 0.6 pg of IL-2 in 24 h.
Akiyoshi et al. (1987)interleukin 2lymph nodesProduction of interleukin 2 by human lymph nodes.
Peuchmaur et al. (1991)IL-2lymph nodesEnumeration of lymphokine synthesizing cells indicated heterogeneous IL-2 production among lymph nodes tested; 2 of the 21 had much higher densities of IL-2-producing cells (855 and 570/cm2) than did the remaining 19 (mean, 92 +/- 15/cm2).
Shimizu et al. (1992)IL-2RLNThe RLN (internal iliac lymph nodes) were dissected surgically, and freshly obtained mononuclear (MN) cells were studied to observe interleukin-2 (IL-2) production and lymphokine-activated killer cell and natural-killer cell activities.
Shimizu et al. (1992)IL-2RLNSizofiran augmented IL-2 production of RLN, which was accompanied by a marked increase in the number of cells stained with anti-Leu-3a and IL-2 receptor.
Ohshima et al. (1994)interleukin-2lymph nodesExpression of human T-cell leukaemia virus type I and associated antigens, and interleukin-2 and receptor in lymph nodes of adult T-cell leukaemia/lymphoma.
Devergne et al. (1992)IL-2lymph nodesWe detected cells expressing interleukin-1 beta (IL-1 beta), tumor necrosis factor-alpha (TNF-alpha), IL-6, IL-2, and interferon-gamma (IFN-gamma) genes in all lymph nodes.
Letessier et al. (1990)IL2LNLMitogen-induced IL2 production was normal in LNL.
Obi (1991)IL-2lymph nodesThe results were as follows: 1) In the metastatic lymph nodes, proportions of T-lymphocyte subsets, production of IL-2 and responsiveness to IL-2 did not change after local administration of OK-432 or Lentinan. 2) In the non-metastatic lymph nodes, percentage of CD4+4B4+ cells were significantly increased and production of IL-2 was markedly augmented after local injection of OK-432.
Vlock et al. (1994)IL-2lymph nodesPatients received daily IL-2 injected perilesionally in divided doses in each of four quadrants and bilaterally into the superior jugular lymph nodes.
Matsushita et al. (1996)IL-2lymph nodeWe investigated the effect of interleukin-2 (IL-2) on tumor growth of primary adult T-cell leukemia/lymphoma (ATL) cells in biopsied lymph node cells obtained from 14 patients (seven [corrected] with acute-type disease, one with chronic-type disease and six [corrected] with lymphoma-type disease).
Kano et al. (1996)interleukin 2lymph nodesThe regional lymph nodes were dissected surgically, and freshly obtained mononuclear cells were studied to investigate the interleukin 2 (IL-2) production, the LAK and NK activities, and the quantitative analysis of the surface phenotype of the mononuclear cells.
Kano et al. (1996)IL-2lymph nodesThe results indicated that SPG enhanced immunological activities in the regional lymph nodes, as shown by increased IL-2 production and cytotoxic activities of the effector cells (NK, LAK), and increased helper T lymphocytes (CD4+) in the tumor-uninvolved lymph nodes.
Hayama et al. (1984)interleukin 2lymph nodeProduction of interleukin 2 (IL-2) in mixed lymphocyte cultures of SJL/J lymph node (LN) and gamma-irradiated, syngeneic lymphoma cells of transplantable reticulum cell sarcoma (gamma-RCS) was abolished by pactamycin pretreatment of gamma-RCS.
Baron et al. (1993)interleukin 2lymph nodeThe importance of the expression of VLA-4 for encephalitogenicity is not unique to cloned T cell lines, as similar results were obtained using myelin basic protein-primed lymph node T cells. alpha 4 integrin levels did not affect antigen responsiveness or production of the Th1 cytokines interleukin 2, interferon gamma, and lymphotoxin/tumor necrosis factor beta; and antibodies against alpha 4 integrin did not block antigen recognition in vitro.
Graziosi et al. (1996)IL-2lymph nodeHowever, substantial levels of IL-2 expression were found in mononuclear cells isolated from lymph node.
Emilie et al. (1990)IL-2lymph nodeIL-2- and INF-gamma-producing cells were observed in all lymph node compartments, with a selective enrichment in germinal centers.
Wen et al. (1989)lymphokinelymph nodesVariations in lymphokine generation by individual lymph nodes draining human malignant tumors.
Peuchmaur et al. (1991)lymphokinelymph nodesThe results show that T-cell activation, defined by lymphokine production, occurs in FL lymph nodes in direct contact with malignant B cells.
Saito et al. (1994)lymphokinelymph nodeThe double layer soft agarose clonogenic assay using colony formation of target cells as an endpoint was adapted for the detection of antiproliferative lymphokine production from peripheral blood lymphocytes (PBL) and lymph node lymphocytes (LNL).
Emilie et al. (1990)IL-2-producinglymph nodesThe amount and distribution of IL-1 beta, IL-6-, and IL-2-producing cells in HIV lymph nodes were not different from those found in six HIV unrelated hyperplastic lymph nodes.
Kollmann et al. (1994)interleukin 2lymph nodesSignificantly more of the HIV-1-infected SCID-hu mice expressed mRNA for human tumor necrosis factors alpha and beta, and interleukin 2 in their spleens, lymph nodes, and PBMC than did uninfected SCID-hu mice.
Maggi et al. (1988)lymphokinelymph nodesA large panel of phytohemagglutinin (PHA)-induced T cell clones (690 in total), established from four different human lymphoid tissues (peripheral blood, tonsils, lymph nodes and spleens) by a high-efficiency cloning technique, was characterized according to their pattern of lymphokine production.
Kusugami et al. (1990)IL-2lymph nodesThis study suggests that regional lymph nodes are strategically located near the tumor and the local cells are capable of producing high levels of IL-2 and IFN-gamma.
Chang et al. (2003)IL-2lymph nodesApproximately 7 days later, vaccine-primed lymph nodes (VPLNs) were harvested and the lymphoid cells secondarily activated with anti-CD3 monoclonal antibody and expanded in interleukin 2 (IL-2).
Jailwala et al. (2009)IL-2lymph nodeThey have also shown that the amount of IL-2 produced by autoreactive CD8+ T cells in response to antigen seems to control the size of the lymph node Treg pool [31].
Peuchmaur (1991)IL-2lymph node[Cytokine gene expression (IL-2 and IL-6) in tumoral lymph node pathology].
Miyawaki et al. (1984)IL 2lymph nodesIn the present study, anti-Tac antibody was used to determine the location of cells expressing IL 2 receptors in frozen sections of human lymph nodes and tonsils by means of an immunoperoxidase technique.
Leiva and Lammie (1989)lymphokinelymph nodeSoluble extracts of B. pahangi females and Mf also suppressed mitogen induced lymphokine production by lymph node cells by 66% and 68% respectively.
Blumenthal et al. (1993)IL-2DLNWe hypothesize that DLN cells secrete a factor(s) that is able to suppress immune response through abrogation of Pk-C activity, thereby decreasing AP-1 formation resulting in decreased IL-2 synthesis and IL-2 receptor synthesis.
Ni et al. (2000)IL-2lymph nodeMoreover, cells remaining in the lymph node 8 days after antigen stimulation produce IL-2 with secondary antigenic challenge.
Lunardi-Iskandar et al. (1986)IL 2lymph nodeIn some patients, peripheral blood and lymph node, but not bone marrow, T-CFC were capable of generating colonies in the absence of added growth factors or mitogens, whereas in others, colony formation was obtained with purified interleukin 2 (IL 2) alone.
Serrano et al. (1997)IL2lymph nodesThe patterns of IL2, IFN-gamma, IL4 and IL5 gene expression in Hodgkin's disease and reactive lymph nodes are similar.
Bujdoso et al. (1989)IL2-likelymph nodeThe data suggests a sequential exit of T cell subsets from an antigen-stimulated lymph node and that the appearance of IL2-like activity and IL2-responsive cells in efferent lymph fluid are temporally distinct events.
Daynes et al. (1991)IL-2lymph nodeFreshly isolated lymph node (LN) cells cultured in serum-containing medium were restricted to produce primarily interleukin 2 (IL-2) subsequent to T cell activation.
Barna et al. (1984)lymphokinelymph nodeIn BeO-treated strain 2 and F1 animals, challenge with beryllium salts produced delayed hypersensitivity skin reactivity, and in vitro, enhanced tritiated thymidine uptake and lymphokine production by lymph node cells.
Sun et al. (1996)interleukin 2lymph nodeSuch treatment was as effective in suppressing interleukin 2 production and proliferative responses of lymph node cells to MBP as treatment involving repeated feeding with much larger (50- to 100-fold) doses of free MBP.
Pellegrini et al. (1996)IL-2lymph nodeWe examined the interleukin-2 (IL-2), interferon gamma (IFNgamma), IL-4, IL-6 and tumour necrosis factor alpha levels in serum; the production of IL-4 and IL-2, with and without activating agents, by PBMC, tumour-draining lymph node lymphocytes and tumour cells; and the proliferative response of PBMC to IL-2, IL-4 and anti-CD3 monoclonal antibody (anti-CD3), which were variously combined.
Prakken et al. (2002)interleukin-2lymph nodeNasal administration of alanine 183 did not lead to detectable T cell proliferation or interleukin-2 (IL-2) production in mandibular lymph node cells, while transforming growth factor beta (TGF beta), IL-10, and IL-4 were readily produced.
Orandle et al. (2001)IL-2lymph nodesCytokine gene expression (interleukin-1beta [IL-1beta], IL-2, IL-6, IL-10, gamma interferon [IFN-gamma], and tumor necrosis factor alpha [TNF-alpha]) and viral loads were evaluated by semiquantitative reverse transcription-PCR in lymph nodes of 5 control animals and 28 animals infected with SIVmac251 at the terminal stages of AIDS.
Chang et al. (2003)IL-2VPLNVaccine-primed lymph node (VPLN) cells were secondarily activated with anti-CD3 mAb and expanded in IL-2 for adoptive immunotherapy.
Boyle et al. (1993)IL-2lymph nodeIn this study, lymph node biopsies from eight HIV-infected patients with persistent generalized lymphadenopathy syndrome (PGL) were assessed for IL-1 beta, IL-2, IL-4, IL-6, IL-10, interferon-gamma (IFN-gamma) and tumour necrosis factor-beta (TNF-beta) gene expression using the polymerase chain reaction (PCR).
Kodaka et al. (1989)IL-2lymph nodeHTLV-I viral RNA expression was detected only in one case in which IL-3 mRNA was expressed in both peripheral blood and lymph node cells and a relatively high proportion of leukemic cells expressed IL-2 receptor (p55, Tac).
Homey et al. (1998)IL-2LNCFurther analysis of the LNC cytokine pattern revealed that the production of both Thl (IFN-gamma and IL-2) and Th2 (IL-4) cytokines was dramatically impaired after topical FK506 treatment.
Woo et al. (2007)interleukin-2lymph nodeThe expressions of interferon-gamma, interleukin-2, and interleukin-12 were similar between sentinel and nonsentinel lymph node.
Chensue et al. (1993)IL-2lymph nodeMoreover, treatment increased (50-100%) IL-2, IL-4, IL-10, and IFN-gamma production in the primary response and all but IFN in secondary response lymph node cultures.
To et al. (2000)interleukin 2lymph nodeEight to 10 days later, tumor cell vaccine-draining inguinal lymph nodes were resected, and lymph node lymphocytes were activated with staphylococcal enterotoxin A and expanded in interleukin 2 in vitro.
Guidos et al. (1989)IL-2lymph nodeFor example, the frequency with which cells expressed high levels of J11d or IL-2-R was greatly decreased following culture, whereas the frequency with which high levels of MEL-14, the lymph node homing receptor were expressed were greatly increased.