Viewing negative mentions of localization of Il2 (M. musculus) in T cells

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Buschman and Skamene (1988)IL-2T cellsThe susceptible animals were found to be T cell-unresponsive since they lacked both proliferative and IL-2 secreting specific T cells.
Thomis et al. (1995)IL-2T cellsIn response to mitogenic signals, peripheral T cells in Jak3-deficient mice did not proliferate and secreted small amounts of IL-2.
Smith (2004)IL2T cellsHowever, upon subsequent and more extensive testing of IL2 (-/-) mice, it was found that in the absence of IL2, the marked proliferative expansion of LCMV-induced CD8+ T cells was virtually eliminated, the total cytolytic effector capacity was reduced by > 90%, and IFN-?
Tingjun and Rongliang (2004)IL-2T cellsThe results showed that SSP1 activated T cells to release NO and secrete IL-2 by modulating activity of PKC and level of intracellular free calcium.
Sireci et al. (1999)IL-2T cellsIn this study we report that a single, subcutaneous injection of the peptide emulsified in IFA gave rise to the development of male-specific CD8+ T cells which displayed H-Y-specific proliferative response in vitro and showed a Tc1-type pattern of cytokine production (i.e. they secreted IFN-gamma and IL-2, but not IL-4 and IL-10).
Lai et al. (2009)IL-2T cellsThe results of CFSE analysis showed that CD8+ T cells cultured in the presence of exogenous IL-2 divided more vigorously than those in the absence of IL-2 (Figure 4B).
Socarras et al. (1993)IL-2T cellsSpleens of adult mice of the A strain background that were rendered tolerant as neonates of class II alloantigens only (A.TH tolerant of A.TL, A.TL tolerant of A.TH) contain large numbers of tolerogen-responsive T cells, many of which secrete IL-4, but not IL-2.
Leong et al. (1997)IL-2T cellsVirus-encoded IL-7 dramatically increased splenic cellularity in infected mice and enhanced the proliferative activity of T cells and their capacity to secrete IL-2 and IL-6, but not IFN-gamma, TNF-alpha or IL-4.
Kobie et al. (2006)IL-2T cellCD73 (5'-ectonucleotidase) is expressed by two distinct mouse CD4 T cell populations: CD25+ (FoxP3+) T regulatory (Treg) cells that suppress T cell proliferation but do not secrete IL-2, and CD25- uncommitted primed precursor Th (Thpp) cells that secrete IL-2 but do not suppress in standard Treg suppressor assays.
Ryan et al. (1997)IL-2T cellsIn an investigation of cell-mediated immunity against Bordetella pertussis, we found that B. pertussis infection in infants and in mice was associated with the induction of antigen-specific T cells that secrete IFN-g and IL-2, but not IL-4 or IL-5.
Buzás et al. (1995)IL-2T cellThe PG-specific and arthritogenic T cell hybridoma (5/4E8) expressed TCR-alpha beta + (V beta 4), CD4+, and CD8- phenotypes and belonged to the Th1 subset, as the cells secreted IL-2 and IFN-gamma, but not IL-4 upon PG stimulation, and the response was MHC class II (I-Ad)-restricted.
Ma and Streilein (1999)IL-2T cellsMoreover, while both cultured microglia and conventional APC stimulated T cell proliferation in vitro, microglia directed the responding T cells toward the Th2 pathway in which IL-4, but not IL-2 and IFN-gamma, was secreted.
Nagarkatti et al. (1990)IL-2T cellsThe tumor-infiltrating CD4+ T cells obtained after BCNU-treatment, when further characterized, were found to secrete only IL-2 and IFN-gamma but not IL-4, after tumor-specific stimulation.
Kezuka and Streilein (2000)IL-2T cellsWhen the stimulator PECs were pretreated with TGF-beta2 and then pulsed with OVA, responding OT-1 T cells proliferated even more swiftly, but they secreted significantly less IFN-gamma, IL-2, and TNF-alpha, and no IL-4 or IL-10.
Price et al. (1993)IL-2T cellsHowever, unlike peripheral T cells, thymocytes from infected mice did not release IL-2.
Mahon et al. (1995)IL-2T cellThe majority of T cell clones, as well as polyclonal T cells generated from mice infected or immunized with poliovirus, secreted IL-2 and interferon-gamma, but not IL-4, IL-5, or IL-10, a profile typical of Th1 cells.
Yamashiro et al. (2002)IL-2T cellsUpon antigen stimulation, CD4(+) T cells derived from these mice did not proliferate or secrete IL-2, but secreted TGF-beta1.
Schönlau et al. (2000)IL-2T cellsWhen T cells from infected CD18-/- mice were restimulated with antigen-presenting cells (APC), they released no IL-2 or IL-4, but a little IFN-gamma, associated with lack of proliferation.
Chen et al. (1998)IL-2T cellsThe CD45-specific T cells used secreted Th1 cytokines, but without detectable soluble IL-2.
Davidson et al. (1991)IL-2T cellsIn contrast to normal CD4+ T cells, lpr and gld CD4+ Ly-5(B220)+ T cells proliferated weakly and did not secrete TNF-alpha, IL-2, or, in most experiments, IFN-gamma after stimulation.
Shen and Fujimoto (1996)IL-2T-cellThe CD4+ T-cell clone designated YS1093 secreted interleukin (IL) 4, IL-5, and IL-6, but not IFN-gamma, tumor necrosis factor alpha, or IL-2, thus indicating that the clone belongs to the Th2 type.
Lu et al. (2001)IL-2T cellsT cells stimulated by liver-derived DEC205+B220+D19- cells release both IL-10 and IFN-gamma, small amounts of TGF-beta, and no IL-2 or IL-4, a cytokine profile resembling T regulatory type 1 cells.
Rosenberg et al. (1996)IL-2T cellTo study its function, we established, from tAChR-primed B6 mice, two t alpha 146-162-specific T cell lines (P14Th) which comprised Th2-type cells because they secreted IL-4 but not IL-2.
Yang et al. (1990)IL-2T cellsThe activated T cells are mainly CD4+ and secrete IL-2 and IFN-gamma but no IL-4.
Hansen et al. (2010)IL-2T cellAlthough they have limited proliferative capacity and are unable to secrete IL-2, natural Treg cells exert their suppressive function after stimulation through the T cell receptor, a process that appears to require antigen-presenting cells [13].
Yu and Chiang (2010)IL-2T cellsT cells secreted no IL-2 [62, 65].
Inoue et al. (1991)IL-2T cellsWhen purified CD4-CD8- cells in the LN on day 7 after BCG infection were cultured with sonicated BCG lysate, PPD derived from Mycobacterium tuberculosis or recombinant 65 kDa heat shock protein derived from Mycobacterium bovis, the gamma/delta T cells on this stage significantly proliferated and secreted IL-2 in response to sonicated BCG lysate and PPD but not to 65 kDa heat shock protein.