Viewing negative mentions of gene expression of IL2 (H. sapiens) in mononuclear cells

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Schauf et al. (1993)IL-2 mRNAPBMCPBMC of 7 patients (all of those with systemic symptoms) expressed interferon-gamma mRNA and none expressed IL-2 mRNA.
Murray et al. (1985)IL-2Mononuclear cellsMononuclear cells from only one of 32 (3%) AIDS patients secreted normal levels of IL-2, and 21 (66%) failed to produce any detectable IL-2.
Yoshii and Shinohara (2000)IL-2PBMCPBMC from GBS patients were found to produce little IL-2 and to have a low response to IL-2 soon after the onset, but marked improvement was seen within one month, concomitantly with improvement of neuropathic symptoms.
Zivny et al. (2001)IL-2mononuclear cellsPeripheral blood mononuclear cells stimulated with BGG or OVA expressed IL-2Ralpha chain but not IL-2 mRNA, consistent with T cell anergy.
Haregewoin et al. (1984)IL-2mononuclear cellsWe have recently shown that lepromatous peripheral blood mononuclear cells (PBMC) failed to produce interleukin 2 (IL-2) in response to M. leprae and that T cell-conditioned media (TCM) can reverse the T cell unresponsiveness in a majority of lepromatous leprosy patients (Haregewoin et al. 1983).
Hassan and Reen (1996)IL-2MNCSince no IL-2 was detected in cell lysates, the presence of high levels of IL-2 mRNA and low IL-2 production suggests inability by neonatal MNC to translate IL-2.
Reddy et al. (1984)interleukin 2mononuclear cellsPeripheral blood mononuclear cells from four normal heterosexual men were preincubated overnight in complete medium supplemented with various concentrations of lectin-free interleukin 2 lacking interferon.
Lin et al. (1988)IL-2MNCBefore Thymostimulin treatment, the patient's MNC did not produce sufficient amounts of IL-2 and gamma-IFN.
Reed et al. (1985)IL 2PBMCOur data revealed that although PBMC-proliferation was markedly suppressed by WGA, levels of IL 2 activity in WGA-inhibited cultures were not reduced, but instead were increased, suggesting failure to utilize IL 2.
Zhao et al. (2002)IL-2mononuclear cellsThe fetal mononuclear cells were unable to produce IL-2, IL-4 or IFN-gamma, but spontaneously secreted IL-10, IL-6 and TNF-alphain vitro.
Dooper et al. (2002)IL-2PBMCWe found that tumour necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma) and to a lesser extent interleukin (IL)-10 production was inhibited by all PGE-subtypes in ConA-stimulated PBMC concomitant with unaffected IL-2 levels.
McHugh et al. (1994)IL-2PBMCNonatopic control PBMC also produced IL-6, although at lower levels, but no IL-2 or IFN-gamma.
Gottschalk et al. (1988)IL-2mononuclear cellsAnalysis of interleukin 2 (IL-2) production revealed that none of the peripheral blood mononuclear cells (PBMC) from BMT patients synthesized IL-2 at less than 1.5 months posttransplant.
Doetze et al. (2000)IL-2PBMCOv-specific T cells could be cloned from GEO PBMC which have a unique cytokine profile (no IL-2 but high IL-10 and/or TGF-beta production), similar to the T cell subsets known to suppress ongoing inflammation (T(h)3 and T(r)1), indicating that this cell type which has not been found so far in infectious diseases may be involved in maintaining Ov-specific hyporesponsiveness.
Vingerhoets et al. (1994)IL-2PBMCHigh responders displayed a typical Th1-like profile since their PBMC produced interleukin-2 (IL-2) and gamma-interferon (IFN gamma) and no detectable IL-4 or IL-5 upon stimulation with HBsAg.
Fujihashi et al. (1993)IL-2mononuclear cellsGingival mononuclear cells from chronic inflammatory periodontal tissues produce interleukin (IL)-5 and IL-6 but not IL-2 and IL-4.
Fujihashi et al. (1993)IL-2GMCFurther, the analysis of culture supernatants of GMC also revealed that cells from AP patients spontaneously produced IL-5 and IL-6 but not IL-2 and IL-4.
Fujihashi et al. (1993)IL-2GMCThese results showed that GMC from localized inflammatory tissues in severe stages of AP possess a distinct cytokine profile represented by high levels of IL-5 and IL-6 mRNA expression and protein synthesis, whereas IL-2 and IL-4 were not detected.
Ausiello et al. (1997)interleukin 2PBMCAntigen-stimulated PBMC of responsive wP recipients were characterized by an elevated production of T-helper-cell type 1 cytokines gamma interferon (IFN-gamma) and interleukin 2 (IL-2), low to minimal production of IL-5, and no production of IL-4.
PĂ©rez-Blas et al. (1991)IL-2mononuclear cellsWe describe an infant whose peripheral blood mononuclear cells were unable to proliferate or synthesize IL-2 in response to a mitogenic combination of antibodies directed against CD2 and CD28.
Dong et al. (2008)IL-2PBMCRESULTS: (1) Compared with the cytokine level of normal controls, the level of IFN-gamma, TNF-alpha, and IL-10 of patients with chronic hepatitis C significantly increased (P < 0.05) while IL-2, IL-4, and IL-12 were not detected in the culture supernatant of PBMC from both normal control and patients with chronic hepatitis C. (2) There was no statistically significant difference in secretion of the cytokines among patients with different severity of the disease.