Viewing affirmative mentions of regulation of IL2 (H. sapiens) in blood

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Sirota et al. (1995)interleukin-2bloodThe effect of human colostrum on the production of interleukin-2 (IL-2) and on natural killer (NK) cell activity by peripheral blood mononuclear cells (PBMC) was investigated in 50 healthy women.
Goretski? et al. (1989)interleukin-2blood[Modifying effect of the blood serum from patients with soft-tissue sarcomas on interleukin-2 production and activity].
Freedman et al. (1992)IL-2bloodEvidence for voltage modulation of IL-2 production in mitogen-stimulated human peripheral blood lymphocytes.
Trzonkowski et al. (2001)Interleukin 2bloodThe aim of this study was to look at the possible changes in the blood levels of Interleukin 2 (IL2) during the sexual cycle in generally healthy, young, regularly menstruating women.
Bernier et al. (1989)interleukin-2bloodRadio-immunological study of the regulation of interleukin-2 production in peripheral blood mononuclear cell cultures from normal subjects and rheumatoid arthritis patients.
Zehavi-Willner and Shalit (1989)interleukin-2bloodThe effect of two quinolone derivatives, ciprofloxacin and ofloxacin, on the production of interleukin-2 (IL-2) was studied in human peripheral blood lymphocytes (PBL) and in a T-cell leukemia cell line (Jurkat) following phytohemagglutinin (PHA) stimulation.
Utsugisawa et al. (2003)interleukin-2bloodWe compared the early effects of FK506 on clinical severity, interleukin-2 (IL-2) production by phytohemagglutinin-stimulated peripheral blood mononuclear cells (PBMs), and serum levels of acetylcholine receptor antibodies between myasthenia gravis (MG) patients with elevated (>1250 pg/ml, n = 9) or normal (<1250 pg/mL, n = 10) levels of PBM IL-2 production.
Rossi et al. (1988)IL2bloodWe have previously shown an increased and dysregulated secretion of IL2 in peripheral blood from patients with B-CLL.
Härtel et al. (2004)IL-2 mRNAbloodWhen CsA was added to whole-blood cultures, the influence on IL-2 mRNA expression was comparable to that of tacrolimus in 9 of 11 individuals.
Eriksen et al. (2001)IL-2bloodHere, we study the regulation of IL-2Ralpha expression and STATs in a tumor cell line obtained from peripheral blood from a patient with Sezary syndrome (SS), a leukemic variant of CTCL.
Hermann et al. (1991)interleukin-2bloodThe purpose of the study was to examine the effects of intravesical BCG treatment on the cytotoxicity, interleukin-2 (IL-2) production and distribution of the subsets of peripheral blood mononuclear cells (PBMC) in patients with carcinoma in situ of the bladder.
Combe et al. (1987)interleukin-2bloodThe regulation of interleukin-2 (IL-2) production was investigated using mononuclear cells from synovial fluid (SF) and peripheral blood of 12 patients with classical and active rheumatoid arthritis.
Verheyen et al. (2000)interleukin-2bloodRegulation of interleukin-2 induced interleukin-5 and interleukin-13 production in human peripheral blood mononuclear cells.
Yoshimura et al. (1998)IL-2bloodEffects of phosphodiesterase (PDE) inhibitors on the production of IFN-gamma, IL-2, IL-4 and IL-5 by phytohemagglutinin (PHA)-stimulated human peripheral blood mononuclear cells (PBMC) were investigated.
Glaser et al. (1990)interleukin 2bloodPsychological stress-induced modulation of interleukin 2 receptor gene expression and interleukin 2 production in peripheral blood leukocytes.
Manolagas et al. (1986)IL-2bloodWe used peripheral blood mononuclear cells (PBM) activated in vitro with phytohemagglutinin to study 1) the relationship between 1,25(OH)2D3 receptor expression, IL-2 production, and 1,25(OH)2D3-induced inhibition of PBM proliferation in connection with the cell cycle; 2) the effect of 1,25(OH)2D3 on PBM activation and on the expression of activation-related molecules including the IL-2 receptor, and 3) the role of calcium in the antiproliferative effect of the hormone. 1,25(OH)2D3 receptor expression occurred when PBM entered the G1a phase of the cell cycle.
Jira et al. (1987)IL-2bloodTo investigate the effect of human recombinant IL-2 on proliferative and cytotoxic responses in burn patients, peripheral blood mononuclear cells from 20 severely burned patients (body surface area (BSA) greater than 20 per cent) were studied in this way.
Briggs et al. (1999)IL-2bloodEffects of glucocorticoids and cyclosporine on IL-2 and I kappa B alpha mRNA expression in human peripheral blood mononuclear cells.
Shah et al. (1991)IL-2bloodOur results demonstrated that the IL-2 expanded cells evidenced the immunoregulatory defect for IL-2 synthesis that we had initially defined using virgin T cells from peripheral blood.
Yron et al. (1986)IL-2bloodWe report on alterations in IL-2 production and cell proliferation following PHA stimulation of peripheral blood lymphocytes (PBL) from stage-I endometrial carcinoma (EC) patients, and on mechanisms involved in these alterations.
Melioli et al. (1988)IL-2bloodThe aim of the present study was to evaluate the effects of intraperitoneal interleukin-2 (IL-2) infusion on tumor-associated lymphocytes (TAL) and peripheral blood lymphocytes (PBL) in patients with malignant ascites.
Fox et al. (1985)IL 2bloodBecause abnormalities in interleukin 2 (IL 2) production have been reported in the blood of patients with certain autoimmune diseases, we have examined the lymphocytes from patients with Sjögren's syndrome (SS) in which it is possible to obtain simultaneous samples of inflammatory site (i.e., salivary gland) lymphocytes and blood lymphocytes.
Schaecher et al. (2001)IL-2bloodThe effects of calpain inhibition upon IL-2 and CD25 expression in human peripheral blood mononuclear cells.
Kamikawa et al. (2008)IL-2bloodThe purpose of the present study is to determine the change in blood concentration of interleukin-2 (IL-2) after intravenous injection in hemodialysis patients and to assess its safety.
Jiao et al. (1998)interleukin-2blood[Effects of smoking on interleukin-2 and its receptor system in human peripheral blood].
Fujino et al. (1997)interleukin-2bloodStimulatory roles of muscarinic acetylcholine receptors on T cell antigen receptor/CD3 complex-mediated interleukin-2 production in human peripheral blood lymphocytes.
Lissoni et al. (1996)IL-2bloodCorrelation between IL-12 and IL-2 blood levels in the metastatic neoplastic disease: a possible inhibitory feedback system regulating their secretion.
Bubeník et al. (1988)interleukin 2bloodDefect in lectin-induced interleukin 2 production by peripheral blood lymphocytes of patients with invasive urinary bladder carcinoma.
Szopi?ski et al. (2001)IL-2blood[The effect of small cell lung cancer extension on secretion of interleukin-2 (IL-2) and interferon gamma (IFM gamma) in whole blood culture stimulated with mitogens].
Ernst et al. (1986)IL-2bloodEffects of systemic in vivo interleukin-2 (IL-2) reconstitution in patients with acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC) on phenotypes and functions of peripheral blood mononuclear cells (PBMC).
Kashiwado et al. (1987)IL-2bloodWe studied the effects of a factor present in rheumatoid arthritis (RA) synovial fluid (SF) on interleukin-2 (IL-2)-dependent cell proliferation and on the production of IL-2 by mitogen-stimulated peripheral blood mononuclear cells.
Komorowski et al. (1997)IL-2bloodEffect of luteinizing hormone alpha-subunit on IL-2 and sIL-2R in vitro secretions from human peripheral blood mononuclear cells.
Stachowski et al. (1990)IL-2bloodThe following parameters were studied: 1) Effect of HBV-IC (HBsAg-IgG or HBeAg-IgG) on PHA-mediated lymphocyte proliferation; 2) Influence of HBV-IC on the ability of PHA-stimulated peripheral blood lymphocytes (PBL) for IL-2 production and IL-2 receptor expression.
Wu et al. (1994)IL-2bloodThis paper deals with the observation of acupuncture therapy affecting interleukin-2(IL-2 level and natural killer (NK) cell immunoactivity in the peripheral blood of patients with malignant tumors.
Cohney et al. (1999)IL-2bloodHere we report SOCS-3 expression in response to IL-2 in both T-cell lines and human peripheral blood lymphocytes.
Menzel et al. (1993)PEG-IL-2bloodAssessment of cytokine levels, phenotypic analyses and differential blood counts were performed to investigate the effects of PEG-IL-2 in-vivo.
Soulillou et al. (1985)interleukin 2bloodDefect in lectin-induced interleukin 2 (IL-2) production by peripheral blood lymphocytes of patients with Hodgkin's disease.
Riesbeck (1999)IL-2bloodIn this study, we wanted to investigate whether cisplatin interferes with the IL-2, IL-2 receptor (IL-2R), interferon (IFN)-gamma, and TNF-alpha expression in phytohemagglutinin-stimulated human peripheral blood lymphocytes.
Panelli et al. (2002)IL-2bloodGenes whose expression is consistently altered in peripheral blood following IL-2 administration
Lissoni et al. (1998)IL-2bloodSince the pineal gland has been proven to stimulate IL-2 endogenous production, the nocturnal increase in IL-2 blood concentrations could depend at least in part on the promoting action of MLT, whose release increases during the dark period of the day.
Balbi et al. (1993)IL-2PBLIn contrast, in PBL mononuclear cell cultures, TMD induced a further increase of the cell proliferation due to the T-cell mitogens interleukin-2 (IL-2) or phytohaemagglutinin (PHA) (p < 0.05 vs each control culture with mitogens) or anti-CD3 antibodies (p < 0.03 vs control cultures).
Kikuchi et al. (1988)interleukin-2bloodThe effects of PSK on OKT 4/OKT 8 cell ratio, interleukin-2 (IL-2) production and expression of IL-2 receptor were examined in peripheral blood lymphocytes (PBL) from patients with advanced ovarian cancer during the course of chemotherapy.
Tisi et al. (1992)IL-2bloodIn addition to IL-2 cell surface receptor, a soluble form of IL-2 receptor (SIL-2R) may be released in the blood and potentially be involved in the regulation of IL-2 availability.
Kay et al. (1990)interleukin-2bloodHis intact, purified blood T cells had a normal proliferative response to phytohemagglutinin and interleukin-2 (IL-2), provided help for B-cell proliferation at control levels and exposure to IL-2 resulted in generation of cytotoxic cells.
Mantovani et al. (1988)interleukin-2bloodThe aims of the investigation were 1) to determine if there are defects in interleukin-2 (IL-2) regulation on either phytohemagglutinin (PHA)-activated or non-PHA-activated peripheral blood mononuclear cells (PBMC) in cancer patients to ascertain the role of IL-2 in this disease; 2) to carry out preliminary experiments for a direct quantitative evaluation of endogenous IL-2 production by PBMC cultures; and 3) to evaluate the IL-2 receptor expression by PBMC of cancer patients.
Luo et al. (2000)IL-2BloodBlood samples were collected before CPB, right after CPB and on the 1st, 3rd and 7th postoperative day (POD) for serum IL-2 and sIL-2R determination.
Goretski? et al. (1989)IL-2LPBAutological serum had either suppressive or stimulative effect on LPB IL-2 production in the observed patients.
Hughes and Pober (1996)interleukin-2bloodTranscriptional regulation of the interleukin-2 gene in normal human peripheral blood T cells.
Drela et al. (2004)IL-2bloodThe results of investigations performed in other laboratories showed that peripheral blood lymphocytes isolated from active elderly demonstrated higher proliferative response to polyclonal mitogens and higher rates of IL-2, IFN-?
Bloehr et al. (1992)interleukin 2bloodThe effect of triiodothyronine (T3) on the responses to mitogens and on the production of prostaglandin E2 and interleukin 2 were studied in serum-free cultures of peripheral blood mononuclear cells (PBMC) in 20 patients undergoing hemodialysis and in 30 control subjects.
Combe et al. (1987)IL-2bloodIndomethacin, phorbol myristate acetate and irradiation of suppressor cells increased IL-2 values in rheumatoid SF and peripheral blood but did not restore normal IL-2 production.
McAllister et al. (1995)interleukin-2bloodLevels of CSF interleukin-2 appear to be affected by relapse mechanisms, while peripheral blood levels are not.
Rouveix et al. (1987)lymphokinebloodThe effects of penicillin, cephalothin and cefoxitin on lymphokine production and mitogen stimulation of human peripheral blood lymphocytes and suppressor cell functions in man were studied with concentrations achievable in serum.
Ueno et al. (1985)lymphokinebloodOntogenic development and the lymphokine responsiveness of human NK cell activity against K562 target cells in peripheral blood lymphocytes were evaluated in fetuses, premature infants, and term neonates by using a 4-hr 51Cr-release assay.
Wu et al. (1994)interleukin-2bloodThe effect of in vitro glutathione (GSH) supplementation on mitogenic response, interleukin-1, interleukin-2 and prostaglandin E2 production, and cellular GSH level in peripheral blood mononuclear cells (PBMC) from healthy young and old human subjects was studied.
Lahat et al. (1993)IL-2bloodIL-2 values were highest in those patients who underwent open-heart surgery and received blood transfusions.
Nakamura et al. (1994)IL-2bloodThe % change in IL-2 production (%IL-2) in GII on 3 days after the operation was significantly correlated to the amount of blood transfusion (r = -0.7, p = 0.0077) but that in GI was not.
Cimino et al. (1989)IL-2bloodSera collected from 40 healthy blood donors were used for normal values, and sera from 33 medical volunteers over 48 years of age (median age 52 years) for normal IL-2 values in the elderly.
Ansorge et al. (2003)IL-2bloodIn detail, we measured the effects on DNA synthesis and production of different types of cytokines, namely IL-1beta, IL-12, IL-2, IL-4, IL-10 and TGF-beta1, of mitogen-activated peripheral blood mononuclear cells (PBMC) as well as of purified T lymphocytes.
Dobozy et al. (1982)lymphokinebloodRegulation of lymphokine production in peripheral blood mononuclear cell cultures.
Liu et al. (2001)IL-2bloodIn order to investigate the role of the expression of the Fas/FasL in peripheral blood lymphocytes (PBLC) and the level of IL-2 in serum of patients with condyloma acuminata (CA) in the immune pathogenesis of CA, flow cytometry, indirect immunofluorescence labeling and ELISA were performed to detect the expression of the apoptotic regulatory proteins Fas/FasL in PBLC and the level of IL-2 in serum of 60 patients with different course of CA.
Stypu?a et al. (1996)IL-2bloodWe examined the plasma concentrations of IL-1, IL-2, IL-6 and blood levels of ACTH, cortisol and prolactin of 21 patients with PD without any previous treatment.
Goulas et al. (2006)interleukin-2bloodEffect of blood transfusion on gene expression of transforming growth factor beta-1 and the alpha subunit of interleukin-2 receptor in a model of colonic wound healing.
Carbonnel et al. (1994)interleukin-2bloodAn as yet undescribed t(4;16)(q26;p13) translocation, involving the region where the interleukin-2 (IL-2) gene has been mapped, was present in the mesenteric lymph nodes and peripheral blood lymphocytes.
Lagoo et al. (1996)interleukin-2bloodMETHODS: We used the polymerase chain reaction to semiquantitatively measure changes in the amount of messenger RNA from the interleukin-1 beta, interleukin-2, interleukin-4, interleukin-6, interleukin-10, tumor necrosis factor-alpha, interferon-gamma, interleukin-1 receptor antagonist, and the interleukin-2 receptor genes in the peripheral blood and endomyocardium of cardiac allograft recipients during the first 8 weeks after transplantation.
Taira et al. (2008)interleukin 2bloodInfluence of bacterial superantigen TSST-1 against the anti-proliferative efficacy of immunosuppressive drugs and interleukin 2 production in peripheral blood mononuclear cells of hemodialysis patients and healthy subjects.
Huang et al. (1988)IL-2bloodThe serum levels of IL-2R were also frequently increased, even in less active SLE. 3) In cell culture experiments, the IgG secretion by purified B cells from 6 of 9 patients with active SLE was increased by autologous T cells acting either alone (3 patients) or synergistically with rIL-2 (3 patients); the B cells from all 9 patients showed increased IL-2 responsiveness compared with blood donor B cells.
Smith and Roberts-Thomson (1989)IL-2bloodPeripheral blood and synovial fluid (SF) mononuclear cells from 30 patients with rheumatoid arthritis (RA) were hyporesponsive to mitogenic stimulation with plant lectins and CD3 antibodies, due to depressed interleukin 2 (IL-2) production and IL-2 receptor upregulation.
Watanobe et al. (1998)IL-2bloodIn order to know more about the in vivo secretion of various cytokines from the human pituitary, this study measured the concentrations of interleukin (IL)-1alpha, IL-1beta, IL-2, IL-6, tumor necrosis factor-alpha and IL-1 receptor antagonist (ra) in both the peripheral blood and the cavernous sinus (CS) plasma from six patients with Cushing's disease before and after an intravenous bolus injection of human corticotropin-releasing hormone (CRH, 100 microg).
Kamogawa et al. (2009)interleukin-2bloodThe concentrations of interleukin-2, -4, -5, -10 and -12p70 in the supernatant of the superantigen-stimulated peripheral-blood mononuclear cells cultured for 24 h and the concentrations for interleukin-1beta and -12p70 in the supernatant cultured for 72 h, respectively, decreased significantly in the presence of 50 microM roxithromycin (P<0.05).
Krohn et al. (1999)interleukin-2bloodOBJECTIVE: To measure the concentration of the cytokines interleukin-1beta (IL-1beta), interleukin-2 (IL-2), interleukin-6 (IL-6), interleukin-10 (IL-10), and tumour necrosis factor-alpha (TNF-alpha) and the modulators of their function interleukin-1 receptor antagonist (IL-1Ra), interleukin-2 soluble receptor alpha (IL-2 sRalpha), interleukin-6 soluble receptor (IL-6sR) and soluble tumour necrosis factor receptor I (sTNFR-I) in systemic and drained blood for the first six hours after a major orthopaedic operation.
Androsova et al. (2001)IL-2bloodIt is suggested that IL-2 accumulation in the blood serum in these patients is strongly influenced by a significant decrease of siL-2R serum concentration.
Watzl et al. (1991)IL-2bloodPsychoactive delta-9-tetrahydrocannabinol (THC) and nonpsychoactive cannabidiol (CBD) were added to cultures of mitogen-activated human peripheral blood mononuclear cells (PBMC) and the concentrations of IL-1, TNF, IFN and IL-2 in culture supernatants were measured by ELISA systems.
Yuzawa et al. (2003)interleukin-2bloodMETHODS: The effects of APC0576 on interleukin-2 production and proliferative responses in human peripheral blood mononuclear cells were studied under various stimuli with in vitro culture assay.