Viewing affirmative mentions of localization of IL2 (H. sapiens) in monocytes

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Childerstone et al. (1989)IL2monocytesThe results suggest that epitope-linked clusters of monocytes, TT-sensitized CD4 and SP-sensitized CD4 cells enable IL2 released by the TT-sensitized CD4 cells to stimulate the SP-sensitized CD4 cells that produce inadequate amounts of IL2.
Vakkila and Hurme (1990)IL-2monocytesWe studied the mechanisms by which human blood-derived dendritic cells (DC) and monocytes induce IL-2R and stimulate IL-2 secretion in autologous and allogeneic mixed luecocyte reaction (auto- and allo-MLR, respectively).
Vakkila and Hurme (1990)IL-2monocytesThe stimulatory properties of monocytes were more complicated: although they stimulated the proliferation in allogeneic MLR, the proliferation rates, duration, and amount of IL-2 secretion were different than in DC-induced MLR.
Arenzana-Seisdedos et al. (1987)IL 2monocytesProstaglandins produced by activated monocytes can block IL 2 and IFN gamma secretion.
Hinze-Selch et al. (1997)interleukin 2monocytesSquirrel monkey monocytes secreted a more than 100-fold lower level of interleukin-1 beta (IL-1 beta) but a four-fold higher level of transforming growth factor beta (TGF-beta) than human monocytes, whereas the secretion of other cytokines, such as tumor necrosis factor alpha (TNF-alpha), TNF-beta and interleukin 2 (IL-2), did not differ between squirrel monkeys and humans.
Orvieto et al. (2003)IL-2monocytesPROBLEM: To determine whether human chorionic gonadotropin (hCG) modulates the in vitro release of interleukin (IL-2) from human peripheral lymphocytes and monocytes derived from patients undergoing controlled ovarian hyperstimulation (COH).
Martin et al. (1986)IL 2monocytesBy itself, antibody 9.3 had no detectable effect on either IL 2 receptor expression or IL 2 release, and did not cause T cell proliferation even when monocytes were present and exogenous IL 2 was provided, indicating that binding of antibody 9.3 does not provide a primary signal for T cell activation.
Ennen et al. (1989)IL 2monocytesWe examined the effect of interleukin 2 (IL 2) on the capacity of human monocytes to secrete reactive oxygen species triggered via Fc-gamma receptor (Fc gamma R) function as measured by chemiluminescence (CL).
Ennen et al. (1991)IL2monocytesThe effect of interleukin 2 (IL2) on the capability of human monocytes to secrete reactive oxygen species triggered via Fc-gamma receptor (Fc-gamma R) function had been investigated by measurement of chemiluminescence (CL).
Maniť et al. (1993)IL-2MonocyteMonocyte activation was monitored by measuring IL-1 beta production, whereas IL-2 secretion reflected Jurkat activation.
Ellner (1991)interleukin-2monocytesIncreased expression and release of interleukin-2 receptors and transforming growth-factor beta are associated with and may contribute to such suppression by monocytes.
Scheinberg et al. (1990)IL-2monocytesThe data show that Tenoxicam inhibits the neutrophil and monocyte functional chemotactic response in vitro, and to some extent in vivo for monocytes, but has no effect on the expression of IL-2 receptors or IL-1 release.
Martin et al. (1986)IL 2monocytesAntibody 9.3 enabled anti-CD3-Sepharose-activated T cells and anti-CD3 antibody-activated Jurkat cells to release IL 2 in the absence of monocytes.
Epling-Burnette et al. (1993)IL-2-inducedmonocytesTherefore, we conclude that IL-2-induced release of GM-CSF is mediated by IL-2R beta, which then acts to modulate the susceptibility of monocytes to lysis by LAK cells.
Gepner et al. (1989)IL-2monocytesIn contrast, IL-1 production by RA monocytes was not affected by CsA and 1,25(OH)2D3, either together or alone, and addition of IL-1 did not restore the ability of CD4+ cells from RA patients to secrete IL-2.
Fleischer et al. (2002)IL-2monocytesHowever, inhibition of T cell functions such as proliferation, IL-2 release, and IL-2 mRNA production did also occur when isolated T cells were activated in the absence of monocytes with immobilized Abs directed against CD3 in combination with cross-linked anti-CD28 Abs.
Blasco et al. (1995)IL-2monocytesJacalin induced interferon-gamma and high IL-6 secretion, mostly by monocytes, and no detectable IL-2 synthesis or secretion by PBMC.
Lagoo et al. (1994)IL-2monocytesSecretion of IL-2, IL-4, and IFN-gamma, as well as DNA synthesis, on the other hand, required the presence of monocytes.
Economou et al. (1989)IL-2monocytesPurified human and murine monocytes can be activated in vitro by human recombinant IL-2 to secrete tumour necrosis factor (TNF).
Homolka et al. (2003)IL-2monocyteWe chose tumor necrosis factor-alpha (TNFalpha) since it is a cytokine predominantly secreted by cells of the monocyte/macrophage lineage and interleukin-2 (IL-2) exclusively by T lymphocytes.
Fattorossi et al. (1991)IL-2monocytesWe evaluated the effect of timing of BE addition to the culture medium on thymidine uptake, the kinetics of expression of activation markers (CD69, CD25 and CD71) on CD4+ and CD8+ lymphocytes, and of class II MHC antigens on CD14+ cells (monocytes), the kinetics of interleukin-1 (IL-1), interleukin-2 (IL-2) and interferon gamma (IFN-gamma) release, and the cell cycle.
Wolf et al. (1977)lymphokinemonocytesAn inhibitor of lymphocyte proliferation and lymphokine production released by unstimulated foetal monocytes.
Herrmann et al. (1989)Interleukin-2monocytesInterleukin-2 and interferon-gamma recruit different subsets of human peripheral blood monocytes to secrete interleukin-1 beta and tumour necrosis factor-alpha.
Eugui and Almquist (1990)IL-2monocytesSome monoclonal antibodies (mAbs) against interleukin (IL) 1 alpha have been found to activate antigen-presenting cells (APC, human peripheral blood monocytes and B lymphocytes), so that unstimulated T lymphocytes cultured with them are induced to proliferate and secrete IL-2.
Antonaci and Jirillo (1985)lymphokinemonocytesThese data were further supported by experiments which showed that stimulation of PBMC by purified homologous LPS led to the release of a chemotactic lymphokine (CLK) for human monocytes.
Wierenga et al. (1990)IL-2monocytesSecretion of IL-2, IL-4, and IFN-gamma was determined after specific stimulation of these TLC, using autologous monocytes as APC.
Herrmann et al. (1989)IL-2PBMOThe present study was aimed to investigate whether IFN-gamma and IL-2 will favour the release of IL-1 beta and TNF-alpha by different subsets of human PBMO.
Hoffman et al. (1990)lymphokinemonocyteAgents which stimulate AA release also initiate other monocyte functions, including generation of reactive oxygen intermediates and lymphokine release.
Sapolsky et al. (1987)lymphokinemonocyteSpecifically, secretion of interleukin-1 (IL-1), a monocyte lymphokine secreted after infection, appears at least in part responsible for this effect.
Jin and Wang (2003)IL-2-inducedmonocytesIt is possible that such different response stems from polymorphisms in the IL-2 receptor and/or down-stream signaling molecules that determine the secretion of cytokine from IL-2-induced monocytes.
Gascan and Lemetayer (1991)IL-2monocyteSeveral other chemical reagents and a panel of recombinant cytokines including IL-2, -3, -4, -5, and -6, granulocyte monocyte colony-stimulating factor (GM-CSF), monocyte-CSF (M-CSF), tumor necrosis factor-alpha (TNF-alpha), and interferon-gamma (IFN-gamma) were tested for their induction of LIF secretion.
Caccavo et al. (2002)IL-2monocyteLactoferrin exerts a bactericidal activity by damaging the outermembrane of Gram-negative bacteria, as well as immunoregulatory functions by decreasing the release of interleukin-l (IL- 1), IL-2 and tumor necrosis factor-alpha INF-alpha) and enhancing monocyte and natural killer cell cytotoxicity.
Kostura et al. (1989)lymphokinemonocytesInterleukin 1 (IL-1) is a lymphokine secreted by monocytes in response to a variety of inflammatory stimuli.
Chen et al. (2009)interleukin-2monocyteMicroRNA-125a-5p was found to mediate lipid uptake and to decrease the secretion of some inflammatory cytokines (interleukin-2, interleukin-6, tumour necrosis factor-alpha, transforming growth factor-beta) in oxLDL-stimulated monocyte-derived macrophages.
Shore et al. (1986)interleukin 2monocytesTwenty-one patients with rheumatoid arthritis (RA) and 12 age and sex matched healthy controls were examined for the ability of their monocytes (adherent cells, AC) to spontaneously secrete interleukin 1 (IL-1) and for their peripheral blood mononuclear cells (PBMC) to secrete interleukin 2 (IL-2) induced by Staphylococcal Protein A (SPA).
Turgut et al. (2006)IL-2monocytesThe aim of this study was to determine the effects of multidrug treatment on serum levels of interleukin-2 (IL-2), secreted by activated T cells, and of neopterin, secreted by macrophages and monocytes, in patients with pulmonary tuberculosis.
Raziuddin et al. (1991)IL-2-andmonocytesThus, S. haematobium-specific CD4+ T cells are present in schistosomiasis, and their function is determined by adequate release of IL-2-and/or IL-2R-bearing CD11+ suppressor monocytes.
Gerrard et al. (1984)lymphokinemonocyteOther monocyte stimulants, including lipopolysaccharide (LPS), lymphokine, and gamma interferon, were examined for their effect on monocyte DR expression and their effect on monocyte antigen presentation.
Scholzen et al. (2009)IL-2monocyteInstead, monocyte/MHC class II interaction with helper CD4 T cells was critical to initiate the secretion of the soluble mediators IL-2 and IL-10, which were necessary for the induction of Foxp3hi expression in transwell-separated bystander CD4+ T cells (Figure 12).
Schneider et al. (2004)TH1 lymphokineMonocyteMonocyte deactivation (reduced TNF-alpha release and HLA-DR expression) and lymphocyte anergy (impaired mitogenic proliferation and reduced TH1 lymphokine release) were blunted and the incidence and severity of infectious complications were reduced.
Gordon and Lewis (1984)IL-2monocyteThus piroxicam and indomethacin prevented the inhibition by endogenous monocyte-derived PGE2 of IL-2 secretion and activity.
Palmieri et al. (2008)IL-2monocytesThis ability of the silicone oil to cause both acute and chronic recruitment of lymphocytes and monocytes could be explained by its ability to slowly release IL-2 due to the hydrophobic surface of silicone that will cause the denaturing of proteins absorbed into it.
Moldawer et al. (1988)IL-2monocytesDuring inflammation, activated monocytes and lymphocytes synthesize and release many soluble protein mediators, such as interleukin (IL) 1, tumor necrosis factor-alpha, and IL-2.
Nesbit et al. (2010)IL-2monocyteWhen monocyte-derived mature dendritic cells pulsed with T27K (mDC(T27K)) were used for antigen presentation, the frequency of polyfunctional CD4 T lymphocytes did not significantly increase for either group, although mDC(T27K) did significantly increase the concentrations of IL-2 and IFN-gamma released by PBMC from nonimmune donors (P = 0.02).
Ogawa et al. (2008)IL-2monocytesOriginally named "cytokine synthesis inhibitory factor" for its ability to inhibit IFN-gamma and IL-2 production in Th2 cells, it is secreted by monocytes, macrophages, mast cells, T and B lymphocytes, and dendritic cells (DCs).
Katz et al. (1990)IL-2monocyteThe release of lymphocyte-derived mediators such as tumor necrosis factor, interleukin-2 (IL-2), and interferon-alpha and -gamma could not be implicated as a cause of monocyte death.
Luger et al. (1987)IL 2monocytesSince addition of dialysis membrane particles enhanced monocytes to produce more IL 1 as well as lymphocytes to release more IL 2, a direct stimulatory membrane effect is postulated.
McCallum et al. (2007)IL-2monocytesThe number of epoxide moieties correlated with the ability to compete with radiolabeled triptolide for binding to the nuclear extract and with the potency of inhibition of TNFalpha secretion from monocytes, IL-2 secretion from Jurkat cells, and with inhibition of RNA synthesis.
Luger et al. (1988)IL 2monocytesWe conclude that monocytes and T-lymphocytes from patients with diabetes mellitus have a diminished capacity to release IL 1 and IL 2 only later in the course of the disease.
Haufe et al. (2004)IL-2monocytesThe response of lymphocytes and monocytes was determined by means of IL-2 secretion and tissue factor (TF) expression, respectively.
Wei et al. (2007)IL-2monocytesABU-LAO also induces liver cell necrosis and release of cytokines including IL-6, IL-12 and IL-2 from highly purified human peripheral blood monocytes and T cells, respectively.
Eckert et al. (1999)IL-2monocytesIn addition, the expression of the cell surface markers CD44, CD16, CD11a and CD62L on lymphocytes and the secretion of IL-2 and IL-1beta from monocytes was measured.
Fiorucci et al. (2004)IL-2monocytesIn this study, we provide evidence that NCX-4016 delivered to PMBC-derived T lymphocytes and monocytes causes a transitory inhibition of cell respiration and approximately 50% reduction of cellular ATP, which translates in a time-reversible inhibition of cell proliferation and IL-2, IL-4, IL-5, and IFN-gamma secretion.
Hodge et al. (2002)IL-2monocyteMonocyte IL-10 production increased significantly and monocyte tumor necrosis factor-alpha (TNF-alpha), IL-1alpha, IL-6, IL-8, T-cell interferon-gamma (IFN-gamma), IL-2, and TNF-alpha decreased significantly in the presence of >or=10 microg/ml garlic extract.
Thestrup-Pedersen et al. (1990)interleukin-2monocytesInterleukin-1 release from peripheral blood monocytes and soluble interleukin-2 and CD8 receptors in serum from patients with atopic dermatitis.
Villa et al. (1996)IL-2MonocytesMonocytes from Jak3-SCID showed normal cytokine production in response to interleukin-4 (IL-4) (release of IL-1 receptor antagonist) and IL-2 (release of tumor necrosis factor-alpha and IL-8).
Yang and Clark (1989)IL-2-dependentmonocytesThese activities include the potentiation of the IL-2-dependent growth of normal T cells; the potentiation of the IL-2-dependent secretion of IgG by activated B cells; and the potentiation of the activities of eosinophils, basophils, and monocytes.