Viewing negative mentions of regulation of CD4 (H. sapiens) in T cells

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Gabutti et al. (2005)CD4T-lymphocyteCD4+ T-lymphocyte counts and viraemia levels were not negatively affected by vaccination.
Crocker et al. (1987)CD4T cellsThis species heterogeneity indicates that T cells and M phi regulate CD4 antigen expression independently and that CD4 may not be essential for M phi function.
Veazey et al. (2000)CD4T cellHowever, since this particular cell type is present in such small numbers in circulation, its loss does not significantly affect total CD4(+) T cell counts.
de Moraes et al. (2007)CD4T-cellPimecrolimus did not alter CD4(+) and CD8(+) T-cell counts or viral load during the treatment period.
Tewari et al. (1998)CD4T cellThe expressed scFvs had no effect on T cell growth or CD4 expression and bound specifically to HIV-1 p17.
Farrokh-Siar et al. (1999)CD4T-cellsThe passaging of HFRPE cells did not alter their suppressive effect on CD4(+) and CD8(+) T-cells.
Ryan et al. (2002)CD4T cellIn contrast, coincubation with soluble DC-specific ICAM-3-grabbing nonintegrin (CD209) fusion protein as a control had no effect on CD4(+) T cell proliferation or IL-4 and IFN-gamma secretion.
Mekonnen et al. (2005)CD4T cellLow CD4 T cell counts before HIV-1 seroconversion do not affect disease progression in Ethiopian factory workers.
Cohen et al. (1996)CD4T lymphocyteCD4 T lymphocyte counts and all virologic parameters examined remained unchanged regardless of zidovudine treatment status.
Lederman et al. (1998)CD4T lymphocyteDysregulated immune activation was partially corrected by this regimen; however, the perturbed expression of T cell receptor V regions in the CD4 and CD8 T lymphocyte populations was not significantly affected.
Percherancier et al. (2003)CD4T-cellsHIV-1 entry into T-cells is not dependent on CD4 and CCR5 localization to sphingolipid-enriched, detergent-resistant, raft membrane domains.
Czesnikiewicz-Guzik et al. (2008)CD4T cellsIn cross-sectional studies, the phenotypic changes were not qualitatively different for CD4 and CD8 T cells, but occurred much more frequently in CD8 T cells.
Kloverpris et al. (2010)CD4T cellWe report that high concentrations of up to 10% of DMSO for 1 hour do not affect the cell viability, the magnitude or the functional profile of CD4(+) and CD8(+) T cell responses, regardless of antigen specificity and HLA class I restriction.
Litjens et al. (2011)CD4T lymphocyteWith increasing age, the CD4+ T lymphocyte population and the different subsets remained remarkably unaffected in CMV-seronegative persons over a period of 4 to 5 decades (Figure 1B and Figure 2A-D, straight line).
Eylar et al. (1994)CD4T cellIf HIV superantigens exist, our data suggest that they are not responsible for the selective depletion of the CD4+ T cell subset as evaluated by SEB and SEA specificity.
Streif et al. (2004)CD4T cellsAfter MV infection, CD8 T cells are reduced in their proliferative capacity whereas the CD4/CD8 ratio, the number and activation status of CD8 T cells is not affected.
Hioe et al. (2001)CD4BDT cellsHowever, the anti-gp120(CD4BD) MAbs by themselves, or as MAb/gp120 complexes, did not affect the presentation of gp120-derived peptides by the APCs to T cells.
Rerks-Ngarm et al. (2009)CD4T-cellVaccination did not affect the degree of viremia or the CD4+ T-cell count in subjects in whom HIV-1 infection was subsequently diagnosed.
Strauss et al. (2009)CD4T cellsIn contrast, both CD4+CD25+ and CD4+CD25high T cells showed high expansion in the presence of RAPA but did not proliferate in its absence (Figure 2A).
Choy et al. (1999)CD4T-cellsThese data suggest that cytokine gene expression of CD4+ T-cells is not affected at therapeutic concentrations of theophylline and salbutamol, but its suppression is likely to be an important mechanism underlying the therapeutic effect of corticosteroids in asthma.
Teunissen et al. (1993)CD4T cellOur data suggest that UVB radiation neither selectively affects Th1 or Th2 nor CD4 or CD8 T cell subsets.
Aladdin et al. (2001)CD4T-cellThe mean CD4+ T-cell TRF length did not change in any of the two groups.
Estes et al. (2002)CD4T cellsFDCs had little effect on CCR5 or CD4 expression but increased CXCR4 expression on CD4 T cells.
Reimão et al. (1991)CD4T cellAn individual's CD4/CD8 ratio, however, remained unaffected by the repeated removal of large volumes of blood by phlebotomy confirming the existence of a homeostatic regulation of the relative numbers of the two major peripheral T cell pools in man.
van Roon et al. (2003)CD4T cellsproduction of CD4+ T cells in RA patients by IL-7 alone, by IL-4 alone or by IL-7 and IL-4 was not significantly different from healthy controls (Fig. 3, left panel).
Moens et al. (1994)CD4T-lymphocyteThere were no changes in the T-lymphocyte phenotypic markers CD4 and CD8 among the three groups.
Balaji and Nayak (1997)CD4T cellsIn this report, we show that 5-Fluorouracil increases the Interleukin-1 expression upto 2.66 folds without significantly affecting the levels of surface expression of p55 IL-2 receptor on human Peripheral blood mononuclear cells, CD4 and CD8 T cells.
Smith (2006)CD4T-cellThose with little or no change in their CD4+ T-cell counts generally have persistent immune system activation [35].
Scholzen et al. (2009)CD4T cellsImportantly we demonstrate here for the first time, to our best knowledge, that direct TCR stimulation is not strictly required for Foxp3 induction in CD4 T cells by an infectious agent.
Vermeulen et al. (2007)CD4T-cellThere was no change in pVL or CD4+ T-cell count in either the single- or multiple-dosing phase.
Favre et al. (2009)CD4T cellThese changes point to de novo generation of Th1 cells and depletion of multifunctional IL-2 producing CD4+ T cell populations in PTs but not AGMs during acute SIV infection, and suggest that the generalized CD4+ T cell losses observed in the PT are accompanied by selective depletion of Th17 cells.
Yoshimura et al. (2003)CD4T cellCD4(+) and CD8(+) T cell counts and proviral DNA level were not significantly changed after the treatment.
Duhant et al. (2005)CD4T cellsS has no inhibitory effect on CD4+ T cells activation induced by a combination of PMA and anti-CD28, indicating that it must act proximally to TCR activation.
Lacabaratz-Porret et al. (2003)CD4T cellFinally, whether HAART was initiated before or after seroconversion had little effect on HIV-specific CD4(+) and CD8(+) T cell responses.
Cummins et al. (2001)CD4T cellsL-selectin expression was not significantly affected on CD4(+) T cells.
Legoux et al. (2010)CD4T cellWe also identified in all donors CD4 T cells specific for A2/peptide complexes, whose frequencies were not affected by MHC class I expression, but nevertheless correlated with those of their naive CD8 T cell counterparts.
Read et al. (2010)CD4T cellThere were no statistically significant changes in CD4 (Figure 2A) or CD8 (Figure 2B) T cell counts during the study.
Shankar et al. (2000)CD4T-cellIn all subjects tested, freshly isolated CD8 T cells were not cytolytic against peptide-pulsed B lymphoblastoid cell line or primary HIV-infected CD4 T-cell targets.
Edelman (2005)CD4T-cellIn a study of seroconversions in Amsterdam, Goudsmit et al. found that CD4+ T-cell levels did not affect the rate of seroconversions, but once HHV-8 infection had occurred, a decline in CD4+ cells was associated with increasing reactivity against the Orf 65 antigen [46].
Schwartz et al. (1992)CD4T-cellThe levels of expression of cell surface molecules involved in T-cell functions (CD4, CD3, CD28, CD29, IL-2 receptor) were not modified in cell populations expressing Nef.
Maecker (2003)CD4T cellAs such, essentially no effect was observed on CD8 (CD3+CD4-) T cell IL-2 production (panels D and H).
Pido-Lopez et al. (2003)CD4T cellNo notable changes in CD4(+) T cell counts and sjTRECs were seen in patients receiving HAART supplemented with Remune alone.
Sheela et al. (1991)CD4T lymphocytesOur results indicate that certain M. leprae factor(s) specifically modulate(s) CD2, CD4, CD8 and IL-2R but not CD3 on T lymphocytes.
Scholzen et al. (2009)CD4T cellsFoxp3 expression in CD4 T cells was not induced when purified T cells as opposed to whole PBMCs were co-cultured with iRBCs, demonstrating that induction of Foxp3+ CD4 T cells is not due to a direct interaction of T cells with iRBCs but dependent on other cells present in the co-culture system (Figure 5A).
Gangemi et al. (2005)CD4T lymphocytesvitro, while having no effect on naive CD4 T lymphocytes,
Choy et al. (2008)CD4T cellsTreatment with CXCL12 induced expression of both iNOS mRNA and protein in primary human CD8 T cells in a dose-dependent manner, but had no effect on CD4 T cells.
Foster and Garcia (2008)CD4T cellAn additional case of a LTNP is an Italian homosexual whose CD4+ T cell levels have not altered in 20 years of infection and whose viral loads have been steady at the extremely low value of about 200 copies/ml.
Mazurov et al. (2010)CD4T lymphocytesAlthough Raji/CD4 cells are not natural targets for HIV-1 infection, we believe that they do provide an appropriate model system to study HTLV-1 cell-to-cell infection, as B-cells are natural targets for HTLV-1 infection in vivo and in vitro [35],[36],[37],[38],[39] and can form synapses with HTLV-1-infected T lymphocytes in vitro [14].
Eylar et al. (2001)CD4T cellsIn HIV+ blood, a few CD4+ T cells may be masked by soluble gp-120, but this would not affect the CD3+ CD8+ population.
van Leeuwen et al. (2009)CD4T cellsOn the other hand, there were no changes in the number of T cells or their CD4+ and CD8+ subtypes.
Hamdi et al. (2006)CD4T-lymphocyteCirculating CD4+ T-lymphocyte numbers remain unaffected in patients treated with TNF antagonists [43,44].
Hasegawa et al. (2001)CD4T cellsThe proportion of T cells, CD4 and CD8 did not change significantly during music therapy.
Tripathi et al. (2010)CD4T cellIn contrast, effector CD4(+) T cell numbers were not affected by the individual or combined loss of IL-15 and IL-7.
van der Meijden et al. (1998)CD4T cellsGenerally, the observed increases in CD126 did not correlate with CD4 levels in HIV-infected subjects or with disease status, with the exception of CD126 expression on CD8 T cells, which was lower in those HIV-infected subjects that had AIDS.
Leligdowicz et al. (2006)CD4T-lymphocyteHowever, in an African setting, where access to appropriate laboratory facilities and funds is limited, CD4 T-lymphocyte levels are of little value.
Tanriver et al. (2010)CD4T cellsImportantly, the targeting strategy had no detrimental effect on CD4(+)CD25(+)FoxP3(+) T cells, which could potentially be used as an adjunctive cellular therapy.