Viewing negative mentions of regulation of CD8A (H. sapiens) in T cells

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Lacabaratz-Porret et al. (2003)CD8T cellFinally, whether HAART was initiated before or after seroconversion had little effect on HIV-specific CD4(+) and CD8(+) T cell responses.
Tewari et al. (2004)CD8T cellInterestingly, in an acute infection, increasing the viral dose caused significant changes in the epitope hierarchy of the LCMV-specific memory CD8 T cell pool, with no effect on the primary CD8 T cell response.
Farrokh-Siar et al. (1999)CD8T-cellsThe passaging of HFRPE cells did not alter their suppressive effect on CD4(+) and CD8(+) T-cells.
Rep et al. (1997)CD8T cellTreatment resulted in a long-lasting depletion of CD4(pos) T cells but did not affect CD8(pos) T cell numbers.
Vestey et al. (1989)CD8T cellsDepletion of CD8+ T cells did not affect lymphoproliferation to HSV outwith recrudescence (four patients), nor lymphoproliferative responses to another antigen (PPD; five patients) during recrudescence.
Kloverpris et al. (2010)CD8T cellWe report that high concentrations of up to 10% of DMSO for 1 hour do not affect the cell viability, the magnitude or the functional profile of CD4(+) and CD8(+) T cell responses, regardless of antigen specificity and HLA class I restriction.
Couty et al. (2008)CD8T cellReplicating RNA replicon injection induced local recruitment of innate immunity effectors (NK and NKT) to the tumour and did not affect specific CD8+ T cell populations or other myelolymphoid subsets.
Lee et al. (2010)CD8T cellIn a nested cohort of 55 AED-treated patients receiving cART and aviremic, chronic exposure to sodium and calcium channel blocking AEDs was associated with increased CD4+ T cell levels (p <0.05) with no change in CD8+ T cell levels over 12 months from the beginning of AED therapy.
Yoshimura et al. (2003)CD8T cellCD4(+) and CD8(+) T cell counts and proviral DNA level were not significantly changed after the treatment.
Panchanathan et al. (2005)CD8T lymphocytesImportantly, the depletion of CD8+ T lymphocytes during a secondary challenge in IFN-deficient mice does not affect their capacity to clear ECTV, indicating that Ab is critical for the control of a secondary infection.
Lipford et al. (2000)CD8T cellsCostimulation was operative on CD8 T cells but not CD4 T cells.
Kountouras et al. (2000)CD8T lymphocytesPeripheral blood CD3+ CD4+ and CD8+ T lymphocytes were not affected by omeprazole treatment (P > 0.05), whereas the percentage of HLA-DR+ peripheral blood lymphocytes increased significantly post-treatment (P < 0.05).
Moens et al. (1994)CD8T-lymphocyteThere were no changes in the T-lymphocyte phenotypic markers CD4 and CD8 among the three groups.
Weber et al. (2006)CD8T cellOur data suggest that CD8(+) T cell activation induced by antigenic stimulation, a function exquisitely fulfilled by mDC, is unaffected by tryptophan metabolites.
Bouloukaki et al. (2009)CD8T-lymphocytesFurthermore, a previous study on bronchial biopsies showed no difference in CD8+ and CD4+ T-lymphocytes before and after smoking cessation [26].
Lederman et al. (1998)CD8T lymphocyteDysregulated immune activation was partially corrected by this regimen; however, the perturbed expression of T cell receptor V regions in the CD4 and CD8 T lymphocyte populations was not significantly affected.
Oliveira-Prado et al. (2009)CD8T cellsFINDINGS: PBMC from infected patients showed lower frequency of CD4(+) but no change in CD8(+) T cells when compared with the healthy donor group.
Loftenius et al. (1997)CD8T cellThe CD8+ T cell subset is not affected to the same extent.
Teunissen et al. (1993)CD8T cellOur data suggest that UVB radiation neither selectively affects Th1 or Th2 nor CD4 or CD8 T cell subsets.
Rajasekaran et al. (2010)CD8T cellIn this study, we found that the expression of NKG2D was not altered among CD8+ T cell subsets.
Sühwold et al. (2010)CD8T cellsWhilst in primary infection an expansion of peripheral CD4+ T cells was observed, reinfection had no effect on the proportions of CD4+, CD8+ subsets or gammadeltaTCR+ T cells.
Saverino et al. (2004)CD8T cellLysis was not dependent on CD8(+) T cell Ag specificity, MHC-unrestricted and specifically blocked by anti-CD85j and anti-UL18 mAb.
Combe et al. (2005)CD8T-cellHowever, recently CD4(+) T-cell-independent CD8 responses during several microbial infections including those with Toxoplasma gondii have been described, although the mechanism is not understood.
Kalland and Dahlquist (1983)T-cell mitogenT-cellIn contrast, the proliferative response to alloantigens in mixed leukocyte culture and to the T-cell mitogen concanavalin A was unaffected.
Eylar et al. (2001)CD8T cellsIn HIV+ blood, a few CD4+ T cells may be masked by soluble gp-120, but this would not affect the CD3+ CD8+ population.
Brignone et al. (2007)CD8T cellNo CD8+ T cell cytokine response was observed (Figure 1B).
Daniels et al. (2001)CD8T cellThese data suggest that CD8's ability to interact with class I MHC is not fixed and is developmentally regulated through the T cell's glycosylation state.
Wang et al. (2009)CD8T cellUV light did not alter early CD8 T cell activation in the lymph nodes, but rather reduced CD8 T cell expansion at later time points.
Montoya et al. (2007)CD8T cellsThe CD4+ T cell count, CD4/CD8 T cells ratio, and serum viral load were not affected by influenza virus vaccination when pre- vs post-vaccination values were compared.
Lütjen et al. (2006)CD8T cellsCollectively, these findings illustrate that CD4 T cells are not required for the induction and maintenance of parasite-specific CD8 T cells but, depending on the stage of infection, the infected organ and parasite challenge infection regulate the functional activity of intracerebral CD8 T cells.
Cortez-Gonzalez and Zanetti (2007)CD8T cellsThe fact that equal or greater expansion in vitro of CD8 T cells specific for telomerase peptides was found in cancer patients as compared to normal individuals indicates that peripheral tolerance does not affect CD8 T cells specific for this self tumor antigen in a way that prevents these cells from being reactivated in vitro by peptide stimulation.
Greenough et al. (2010)CD8T cellEBV epitope-specific CD8+ T cell proliferative responses to peptide stimulation were diminished during AIM regardless of PD-1 expression and were unaffected by blocking PD-1 interactions with PD-L1.
Liu et al. (2008)CD8T lymphocyteThe percentages of CD4(+)CD8(+) T lymphocyte subsets were also increased by phytase (P < 0.05), without affecting the ratio of CD4(+) and CD8(+).
Sheela et al. (1991)CD8T lymphocytesOur results indicate that certain M. leprae factor(s) specifically modulate(s) CD2, CD4, CD8 and IL-2R but not CD3 on T lymphocytes.
Nateghi Rostami et al. (2010)CD8T cellSimilar to CD4+ T cells, the levels of IL-10 and IL-13 were not significantly different in CD8+ T cell culture between HCL volunteers and healthy controls.
Nateghi Rostami et al. (2010)CD8T cellIn both CD4+ and CD8+ T cell cultures, the changes in the gene expression of IL-5, IL-10 and IL-13 were not significantly different between HCL volunteers and healthy controls.
Canaday et al. (2001)CD8T cellHowever, inhibition of perforin activity, the CD95-CD95L interaction, or both CTL mechanisms did not affect CD4(+) and CD8(+) T cell mediated restriction of MTB growth.
Brod et al. (1990)CD8T cellThese results show that IL-4 can upregulate CD8 expression on CD4+ T cell clones while not effecting CD4 expression on CD8+ T cell clones.
Schroeder et al. (1994)CD8T cellThe binding frequencies (% positive) for anti-CD2, -CD3, -CD5, -CD6, -CD7, -CD8, -CD11a, -CD14, -CD18, -CD19, -CD45, -T cell receptor, and -HLA-DR were not significantly affected.
Turrel-Davin et al. (2010)CD8T cellsWe observed a trend toward an increased Annexin-V binding on CD4+ T cells and CD19+ B cells at D1-2 but no change on CD8+ T cells (Figure 2a).
Hasegawa et al. (2001)CD8T cellsThe proportion of T cells, CD4 and CD8 did not change significantly during music therapy.
Reimão et al. (1991)CD8T cellAn individual's CD4/CD8 ratio, however, remained unaffected by the repeated removal of large volumes of blood by phlebotomy confirming the existence of a homeostatic regulation of the relative numbers of the two major peripheral T cell pools in man.
Czesnikiewicz-Guzik et al. (2008)CD8T cellsIn cross-sectional studies, the phenotypic changes were not qualitatively different for CD4 and CD8 T cells, but occurred much more frequently in CD8 T cells.
Streif et al. (2004)CD8T cellsAfter MV infection, CD8 T cells are reduced in their proliferative capacity whereas the CD4/CD8 ratio, the number and activation status of CD8 T cells is not affected.
Thomas et al. (2003)CD8T lymphocytesPrevious work has shown that the foals' circulating subpopulations of CD4 and CD8 T lymphocytes are unaffected.
Mills et al. (1999)CD8T cellsTreatment with the nonselective beta antagonist propranolol significantly attenuated the preferential increase of circulating CD8(+)CD62L(-) lymphocytes (p = 0.01) but had no effect on CD8(+)CD62L(+) T cells.
Hou et al. (2003)T-cell receptorT-cellInterleukin-12 and interleukin-2-induced invariant natural killer T-cell cytokine secretion and perforin expression independent of T-cell receptor activation.
Thepen et al. (1992)T-cell-independentT-cellWhen the responses against T-cell-independent type 1 and type 2 antigens were compared, it was found that elimination of alveolar macrophages had no effect on T-cell-independent antigens.
Srinivasan and Wolchok (2004)CD8T cellsR), CD4+ cells and NK1.1+ cells, but interestingly was independent of CD8+ T cells [47].
Maecker (2003)CD8T cellAs such, essentially no effect was observed on CD8 (CD3+CD4-) T cell IL-2 production (panels D and H).
Zuo et al. (2010)CD8T cellsIn summary, we found a direct correlation between PD-1 expression on CD8(+) T cells and HIV levels that was not affected by types of medications used in the ART of those adolescents, suggesting that virological success is necessary for PD-1 downregulation.
Dorfman and Germain (2002)CD8T lymphocytesOverall, our analysis of the available data suggests that most or all mature CD4(+) (and perhaps also many CD8(+)) T lymphocytes do not depend on self-recognition for their viability in the periphery.
Boasso et al. (2005)CD8T cellsPretreatment of PBMCs with CTLA-4-Fc inhibited the activation of CD4(+) T cells induced by influenza A virus (Flu) or phytohemagglutinin A (PHA), but had no effect on CD8(+) T cells.
Rager-Zisman et al. (2003)CD8T cellsThe percentages of both CD4(+) and CD8(+) T cells decreased while the CD4:CD8 ratio remained unchanged.
Arasteh et al. (2009)CD8T-cellImmunologic control was maintained, with no significant changes in CD4+ or CD8+ T-cell counts.
Wisuthsarewong and Viravan (2002)CD8T-cellThere were no definite changes in immunological parameters including CD4, CD8 T-cell subpopulations and serum IgE, but eosinophil count showed a mark decrease in one case.
Brooks et al. (2009)CD8T cellIn this study, LMP1 is not itself a CD8(+) T cell target, but its expression enhances Ag-processing capacity and HLA class I expression.
Honey et al. (1999)CD8T cellWhen the CD8+ T cell population is controlled independently, using anti-CD8 Abs, then tolerance is possible.
Habicht et al. (2007)CD8T cellsWhile blocking PD-L1 did not affect the in vivo proliferation of CD4(+) and CD8(+) T cells regardless of CD28 costimulation, blocking PD-L2 resulted in a marked increase in the responder frequency of CD8(+) T-cells in vivo.
Lee et al. (2010)CD8T cellThus, induction of PD-L1 expression seems not involved in HBx-mediated suppression of CD8 T cell activity.
Foote et al. (2005)CD8T cellCD8+ T cell or B cell percentages were not affected by diet.
Poljak (1987)T-cell receptorT-cellNo major conformational change in either MHC antigens or the T-cell receptor takes place as a result of complex formation and antigen recognition.
Porto et al. (1994)CD8T lymphocytesEach individual's CD4/CD8 ratio, as well as the absolute numbers, remained unaffected with time, confirming the existence of a strict homeostatic regulation of the relative numbers of the two major peripheral T lymphocytes.
Janic et al. (2008)CD8T cellThe results showed 1) FePro labeling had no effect on the changes in morphology and expression of cell surface proteins associated with TPA induced differentiation; 2) FePro labeled cells responded to LPS with slightly higher levels of NFkappaB pathway activation, as shown by immunobloting; TNF-alpha secretion and cell surface expression levels of CD54 and CD83 activation markers, under these conditions, were still comparable to the levels observed in non-labeled cells; 3) FePro labeling exhibited differential, chemokine dependent, effect on THP-1 chemotaxis with a decrease in cell directional migration to MCP-1; 4) FePro labeling did not affect the ability of THP-1 cells to down-regulate T cell expression of CD4 and CD8 and to induce T cell proliferation.
Rondelli et al. (2000)CD8T cellDevelopment of acute graft-versus-host disease (GVHD) did not affect CD4:CD8 ratios but patients who experienced acute GVHD > grade I had lower CD4+ and CD8+ T cell numbers at all time points.
Menges et al. (1999)CD8T lymphocytesAnalysis of lymphocyte subsets revealed a fall in total lymphocyte levels, in CD4+ T lymphocytes, and natural killer (NK) cells, but no change in CD8+ T lymphocyte subset.
Brito et al. (2007)CD8T cellHigher levels of chemokines were not related to nadir CD4+ T and current CD8+ T cell counts.
Ciupe et al. (2009)CD8T cellIn humans, transplantation of thymic tissue at varying doses into complete DiGeorge anomaly subjects showed no significant effect on the nave CD4 or CD8 T cell numbers [27].
Fujimaki et al. (2001)CD8T cellsDevelopment of acute GVHD did not affect the numbers of CD4+, CD8+, CD4+ CD45RA+ and CD4+ CD29+ T cells, but the number of CD56+ cells in patients who developed grades II-IV acute GVHD was low.
Mathiot et al. (2001)CD8T cellsProportions of CD3(+)CD4(-)CD8(-) T cells and total gammadeltaT cells were not affected by CD4(+) T cell counts, HAART, or a history of IRD, but levels of CD4(-)CD8(-)gammadeltaTCR(-) T cells were higher in patients with <15% CD4(+) T cells.
Attallah et al. (2003)CD8T-cellsIn addition, LC and HCC patients showed no significant change in CD8 T-cells compared with controls.
Ploss et al. (2005)CD8T cellsIn this study we demonstrate that primary H2-M3-restricted CD8 T cell responses are unaffected by the frequency of naive MHC class Ia-restricted T cells during L. monocytogenes infection.
Qasim et al. (2003)T-cell receptorT-cellAlthough the T-cell receptor Vbeta repertoire was not altered after retroviral transduction, there were notable shifts in subset profiles with an increased proportion of CD45RO cells in transduced populations.
Laschober et al. (2010)CD8T lymphocytesEZH2 levels were not significantly regulated in MSC, PrSC, and CD8 T lymphocytes (Fig. 2B, C) consistent with the results of RNA profiling.
Tohda et al. (2001)CD8T lymphocytesThe results revealed that theophylline administration did not affect the numbers of activated CD4 and CD8 T lymphocytes in peripheral blood.
Emmerich et al. (2008)T-cell receptorT-cellThis alteration neither affects the peptide binding site nor the T-cell receptor (TCR) contact residues.
Artac et al. (2010)CD8T cellsThe CD69 and HLA-DR expressions of T cells and CD8+ T cells were not affected by IVIG infusion.
Kurosaka et al. (2007)T-cell antigen receptorT-cellT-cell antigen receptor assembly and cell surface expression is not affected by treatment with T-cell antigen receptor-alpha chain transmembrane Peptide.
Cuff et al. (1989)T-cell-independentT-cellOur results show that both primary and secondary T-cell-dependent antibody responses are inhibited, whereas both type I and type II T-cell-independent antibody responses are not affected by the suppressor cell population.