Viewing negative mentions of positive regulation of IL2 (H. sapiens) in thymocytes

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d'Hennezel et al. (2010)IL-2thymocytesIn Fontenot et al., the analysis of Foxp3-GFP reporter knock-in mice genetically deficient for IL-2 or IL-2R (CD25) revealed that IL-2 signaling is not required for the induction of Foxp3 expression in thymocytes.
Ueno et al. (1989)interleukin-2thymocytesHuman thymocytes do not respond to interleukin-2 after removal of mature "bright" CD5 positive cells.
Fox et al. (1985)IL 2thymocytesThe triggering of T11 by monoclonal antibodies anti-T112 and anti-T113, directed at two unique epitopes on the molecule, induced IL 2 receptor expression on both T3+ and T3- thymocytes but did not induce IL 2 production.
Matsushima et al. (1985)interleukin 2thymocyteSix of eight human EBV-B cell lines spontaneously produced and released detectable levels of thymocyte comitogenic factor in vitro, but no interleukin 2 (IL-2) activity.
Chang et al. (1991)IL-2thymocytesFor CD4-8- TCR-alpha beta early thymocytes that have not yet entered the selection process, PMA + ionomycin induced significant cell proliferation but little IL-2 production, in the absence of added IL-1.
Turka et al. (1992)interleukin 2thymocytesIn addition, the altered signal transduced by CD2 in TCR/CD3- thymocytes did not lead to a rise in intracellular calcium, failed to induce interleukin 2 receptor expression, and did not serve as a comitogen with phorbol ester or interleukin 2, functions that were all intact in TCR/CD3+ thymocytes.
Papiernik and Jacobson (1986)IL-2-containingthymocytesSmall numbers of cortical (PNA+) thymocytes do not respond to Con A, even in the presence of IL-2-containing supernatant.