Viewing affirmative mentions of gene expression of IL2 (H. sapiens) in CTLL-2

Full-text article links are indicated by after the article reference.

Document Target Regulator Anatomy Sentence
Warrington (1988)IL-2CTLL-2Interleukin-2 (IL-2) production in systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) was assessed at varying cell densities from 3 X 10(3)-1 X 10(5) cells/culture in response to mitogen stimulation, using a cellular interleukin assay in which IL-2 responsive CTLL-2 indicator cells were added directly to stimulated peripheral blood lymphocyte cultures.
Russell et al. (1998)IL-2CTLL-2Neither X-irradiation nor UV-B irradiation of the cultures affected IL-2 produced in the assay or human recombinant IL-2 measured by 3H-TdR incorporation into the IL-2 dependent cell line, CTLL-2.
Weir et al. (1991)IL-2CTLL-2ENO also potently inhibited both IL-2 production (measured by ELISA) and IL-2 responsiveness (measured by CTLL-2 response to IL-2) in a concentration-dependent manner, yet did not inhibit acquisition of IL-2 receptors.
Park and Cheong (2002)interleukin-2CTLL-2A bioassay revealed that human interleukin-2 expressed in the potato tuber supported proliferation of interleukin-2-dependent cells, CTLL-2.
Nagashima et al. (1997)IL-2CTLL-2Stably transduced SCCHN cells produced and secreted IL-2, which was shown to have biologic activity in a bioassay, using an IL-2-dependent CTLL-2 cell line.
Lala et al. (1988)IL-2CTLL-2The results revealed that this suppression was the net result of an action of PGE2 on at least two events during lymphocyte activation: (i) a down-regulation of IL-2 receptor development on lymphocytes, quantitated with a radioimmunoassay and radioautography; this was noted in MLC or Con A-stimulated lymphocyte cultures in the presence of decidual cells (reversible in the presence of indomethacin or anti-PGE2 antibody), or PGE2, but not PGF2 alpha; (ii) an inhibition of IL-2 production in the MLC, measured with a bioassay using an IL-2-dependent T cell line (CTLL-2) and a recombinant IL-2 standard.
Lasek et al. (1989)IL-2CTLL-2The potent stimulatory effect of PMA on IL-2 production by EL-4 cells has been confirmed by measuring 3H-thymidine incorporation by the IL-2-dependent T cell line, CTLL-2, in the presence of conditioned medium (CM) from stimulated cultures.
Burton et al. (1994)IL-2CTLL-2Since CTLL-2 was purported to be IL-2-specific, we performed a number of studies to exclude IL-2 production by HuT-102.
Dao et al. (1994)IL-2CTLL-2IFN-alpha alone had no effect on either the IL-2 production or apoptosis of MOLT-16 cells, but significantly increased both the IL-2 production and apoptosis in the MOLT-16 cells after phytohemagglutinin (PHA) stimulation as determined by CTLL-2 assay and by flow cytometric analysis using propidium iodide (PI) staining.
Shapiro et al. (1990)IL-2CTLL-2Expression of IL-2 sequences in IL-2-dependent mouse CTLL-2 cells resulted in autonomous growth of IL-2-independent CTLL-2 clones.
Davis et al. (2001)IL-2CTLL-2The Basic Protocol describes the use of the CTLL-2 line to detect murine IL-2 and IL-4 in supernatants.
Dore et al. (1997)IL-2CTLL-2Only the chimeric protein desaminated the 28S rRNA and inhibited translation of the CTLL-2 cell line which expresses the IL-2 receptor.
Shimizu et al. (1986)IL-2CTLL-2The human IL-2 receptor, which was expressed on an IL-2-dependent murine T-cell line, CTLL-2, by cDNA transfection, was shown to be functionally active by blocking the endogenous mouse IL-2 receptor with monoclonal antibodies.
Ide et al. (1987)interleukin-2CTLL-2A series of hybridoma cell lines which produce monoclonal antibodies (MAbs) against recombinant human interleukin-2 (rIL-2) have been established by fusion of murine myeloma cell line P3-NS1-1-AG4-1 and spleen cells of BALB/c mice which had been immunized with rIL-2. 48 hybridoma strains were selected by a solid-phase screening method which produced MAbs reacting with IL-2: four MAbs, L-15, L-20, L-34, and L-61, exhibited strong inhibition of the proliferating effect of rIL-2 on IL-2-dependent cell lines, NK7 and CTLL-2.
Cano et al. (1992)IL-2CTLL-2In addition, PA was able to induce c-myc RNA transcription in CTLL-2 cells as well as IL-2 receptor (CD25) expression on the cell membrane with equal potency as saturating doses of IL-2.
Russell et al. (1998)IL-2CTLL-2IL-2 is detected by 3H-thymidine (3H-TdR) incorporation into the IL-2 dependent cell line, CTLL-2.
Hartmann et al. (1989)IL 2CTLL-2Further studies using IL 2 and IL 4 responsive cell lines (CTLL-2 and HT-2) demonstrated that the same anti-PRL antibodies inhibited the proliferative response to these cytokine growth factors.
Davis et al. (2001)IL-2CTLL-2One alternate protocol describes the detection of IL-2 in samples of human serum or supernatants using CTLL-2 cells, while other alternate procedures describe the detection and quantitation of murine IL-4 using a mutagenized subline of CTLL-2, CT.4S, and the detection of human IL-4 using a derivative of the CT.4S mouse cell line, CT.h4S.
Boise et al. (1996)IL-2CTLL-2Introduction of the cell survival gene bcl-xL improves the viability of CTLL-2 cells without affecting their IL-2 proliferative response.
Boise et al. (1996)IL-2CTLL-2However, while overexpression of Bcl-x(L) can prevent CTLL-2 cells from dying in the absence of IL-2, overexpression of Bcl-x(L) does not impair the ability of CTLL-2 cells to be used for proliferation-based IL-2 bioassays.
Trisler and Specter (1994)Interleukin-2-inducedCTLL-2Interleukin-2-induced protein synthesis was also suppressed in a dose related manner over this THC concentration range, with the hPBL being more susceptible to the suppressive effect of THC than the CTLL-2 cells.
Fink et al. (1988)IL-2CTLL-2Specifically interleukin-2 (IL-2)-dependent CTLL-2 cells were incubated in short term culture in the presence of IL-2 together with bombesin and two analogues, [Lys3]bombesin and [Tyr4]bombesin in different concentrations.
Fidelus and Laughter (1986)IL-2CTLL-2IL-2 production or lack of production was established by 3H-uridine and 3H-thymidine incorporation as well as viable cell count using the IL-2 dependent cell line CTLL-2.
Iwanaga et al. (1999)IL-2CTLL-2We examined the effect of Tax activity on the growth of the interleukin-2 (IL-2)-dependent T-cell line CTLL-2.
Saito et al. (1993)IL-2CTLL-2The human H chain-expressing transfectants proliferated in response the human IL-2 in a similar kinetics with CTLL-2.
Kondo et al. (2006)IL-2CTLL-2While the HTLV-2-transformed human T-cell lines produce a significant amount of IL-2, Tax2-transformed CTLL-2 cells only produced a minimal amount of IL-2.
Asselin-Labat et al. (2004)IL-2CTLL-2To assess the functional consequences of this induction, we used 2 strategies, GILZ overexpression and GILZ silencing in murine IL-2-dependent CTLL-2 cells.
Obiri et al. (1990)interleukin-2CTLL-2Levamisole meets sulfhydryl requirements of CTLL-2 cells and mediates enhanced proliferative response to mitogen stimulation without increasing interleukin-2 production.
Obiri et al. (1990)IL-2CTLL-2When the effect of LMS on IL-2 receptor (IL-2R) expression in CTLL-2 cells was examined by a receptor-ligand binding assay involving low levels (10-80 pM) of 125IL-2, a modest increase in the level of IL-2R expression was observed.
Kondo et al. (2006)IL-2CTLL-2While the HTLV-2-transformed human T-cell lines produce a significant amount of IL-2, Tax2-transformed CTLL-2 cells only produced a minimal amount of IL-2.
Tsubata et al. (2005)IL-2CTLL-2Unexpectedly, in spite of three independent trials, we could not establish CTLL-2 cells expressing Tax2B or Tax2B+C even in the presence of IL-2.
Ishioka et al. (2006)IL-2-independentCTLL-2C) greatly reduced IL-2-independent growth mediated by Tax1 in CTLL-2 [25].
Ishioka et al. (2006)IL-2-independentCTLL-2Together, one possible scenario is that Dlg1 inhibits cell cycle progression of CTLL-2/Tax1, but Tax1 through altering localization of Dlg1 in cells, overcome the cell cycle inhibition to initiate IL-2-independent transformation.
Ishioka et al. (2006)IL-2-independentCTLL-2As discussed above, inactivation of one of the two PDZ proteins should be essential for IL-2-independent transformation of CTLL-2 by Tax1, since Dlg1 knockdown did not enhance the frequency of cells transformed by Tax1?
Vine et al. (1988)IL-2CTLL-2The frequency of proliferating T4 cells was assessed by examining wells microscopically, and the frequency of T4 cells producing IL-2 was assessed by examining the ability of supernatants to support CTLL-2 proliferation.
Arai and Matsui (1997)interleukin-2CTLL-2A purified protein from Salmonella typhimurium inhibits high-affinity interleukin-2 receptor expression on CTLL-2 cells.
Wang et al. (2002)IL-2CTLL-2The cytochrome c-sensitive TCR-expressing hybridoma (2B4) was stimulated with pigeon cytochrome c antigen, anti-CD3 crosslinking, or PMA and ionomycin, in the presence or absence of CP, and the resulting IL-2 produced was measured in a bioassay using an IL-2-dependent cell line (CTLL-2).
Sharom et al. (1991)IL-2CTLL-2Low concentrations of cholera toxin B subunit (CT-B), which binds specifically to GM1 ganglioside, greatly inhibited IL-2-stimulated DNA synthesis in the IL-2-dependent cell line CTLL-2, but had no effect on proliferation of HT-2.
Hernández-García et al. (1996)IL-2CTLL-2CD25 expression and production of IL-2 after CD69 activation were assessed by flow cytometry and in a bioassay with the IL-2-dependent cell line CTLL-2.
Zografos et al. (2008)adiponectinTNFliverOBJECTIVES: To compare serum adiponectin and tumor necrosis factor (TNF)-alpha among patients with viral liver diseases; to investigate associations of serum adiponectin and TNF-alpha with histological or viral characteristics of chronic hepatitis C (CHC); to investigate adiponectin and TNF-alpha alterations during interferon (IFN)-alpha treatment; and to assess the relationship between serum adiponectin and TNF-alpha and response rates to treatment.
Sogo et al. (2008)IL-2CTLL-2When the pairs of chimeric receptors (V(H)-IL-2Rbeta and V(L)-IL-2Rgamma, or V(H)-IL-2Rgamma and V(L)-IL-2Rbeta) were expressed in IL-3-dependent pro-B cell line Ba/F3 and IL-2-dependent T cell line CTLL-2, the cognate antigen HEL induced selective expansion of gene-modified cells in the absence of IL-3 and IL-2, respectively.
Grassilli et al. (1999)interleukin 2-dependentCTLL-2To investigate the role of Myb proteins in the regulation of apoptosis, we studied the apoptotic response of interleukin 2-dependent CTLL-2 cells stably transfected with B-Myb.