Viewing negative mentions of binding of CD8A (H. sapiens) in T cells

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Wang et al. (2000)CD8T cellsTogether, our data indicate that, unlike HTLV-1, HTLV-2 cell tropism is not due to inhibition of viral infection and inefficient gene expression in CD4(+) versus CD8(+) T cells, and likely involves unique interactions with viral and CD8(+) T cell-specific proteins.
Lambert et al. (2005)CD8T cellsRESULTS: The CD4dimCD8+ T cells had decreased fluorescence intensity for CD4 but not for CD8.
de Jersey et al. (2007)CD8T cellsRecruitment to the islet milieu does not therefore require cognate interaction between CD8 T cells and MHC class I on mature pAPCs.
Lohman et al. (2005)CD8T-cellThese results suggest that, in contrast to HIV-1-infected adults, in whom strong cytotoxic T lymphocyte responses in primary infection are associated with reductions in viremia, HIV-1-infected neonates generate HIV-1-specific CD8+-T-cell responses early in life that are not clearly associated with improved clinical outcomes.
Pelte et al. (2004)CD8T cellAs a result of this work, we report a potential new T cell target protein, one previously unknown CD8-T cell-stimulating peptide, and an extensive list of CMV-derived potentially strong HLA-A*0201-binding peptides that are not recognized by T cells of HLA-A*0201-positive CMV-seropositive donors.
Kent et al. (1996)CD8T-cellThese CTL, as reflected by studies of cytolytic lines and derived T-cell clones, were CD8+, did not recognize allogeneic targets, and recognized the SIV proteins in the context of class I major histocompatibility complex molecules.
Friedman et al. (2004)CD8T cellsWe demonstrate the presence of both CD4 and CD8 T cells that recognize naturally processed epitopes derived from SOX-4 as well as the presence of SOX-4-specific Abs in sera from SCLC patients, but not in sera from healthy donors.
Panelli et al. (2004)CD8T cellsIn particular, we have focused our interest on the paradoxical observation that active specific immunization consistently induces circulating CD8+ T cells capable of recognizing in ex vivo assays tumor cells, but cannot induce tumor regression alone.
Cruz et al. (2006)CD8T-cellIn a control population not carrying the C282Y mutation, however, combinations of the same HLA-A alleles, as observed in patients, did not reveal the same association with CD8+ T-cell numbers, constituting an argument against this possibility.
Richardson et al. (2002)CD8T-cellAlternatively, Tat specific CD8+ T-cell responses may not appropriately recognize infected cells in vivo in this model.
Ott et al. (1998)CD8T cellsLymphoid cells of the peripheral blood showed an immunophenotype of CD3-positive gamma/delta T cells with a negativity for CD4 and CD8.
Diedrichs-Möhring et al. (1991)CD8T cellsThe activated CD4+ T cells expressed all three class II isotypes (DR, DQ, and DP), whereas the cytotoxic CD8+ T-cell lines expressed DR and DP molecules but failed to bind DQ-specific monoclonal antibodies significantly.
Martinez-Picado et al. (2005)CD8T-cellWe could find no association between in vitro replication capacity and in vivo plasma viral load doubling time and CD4(+) and CD8(+) T-cell counts at each treatment interruption.
Jung et al. (1994)CD8T lymphocytesBoth CD8+ and CD4+ T lymphocytes do not recognize native viral proteins but processed peptides bound to MHC class I and class II, respectively.
Wooldridge et al. (2005)CD8T cellAlthough biophysical studies with soluble proteins show that TCR and CD8 do not bind cooperatively to pMHCI, accumulating evidence suggests that TCR associates with CD8 on the T cell surface.
Sato et al. (2010)CD8T cellsThese results together indicate that the human CD8+ T cells could not recognize alloantigens in the mice.
Erkeller-Yuksel et al. (1997)CD8T cellsWe did not find any association with the CD38+CD8+ T cells and disease activity as measured by BILAG or renal involvement.
Posnett et al. (1986)T-cell antigen receptorT cellsWhile two of these antibodies detect the clonotypic receptor in all individuals studied, the third antibody (OT145), described herein, does not detect the T-cell antigen receptor on T cells of all individuals.
God and Haque (2010)CD8T cellsIt is well established that cytotoxic CD8+ T cells do not efficiently recognize BL cells (whether positive or negative for EBV) and are thus incapable of mounting an immune response [35].
Srinivasan and Wolchok (2004)CD8T cellsMelan-A (MART-1), whose function is not clear, is another melanosomal protein for which CD8+ T cells have been identified [48].
He et al. (2005)CD8T cellsFlow cytometry revealed that these tetramers could specifically bind to CD8(+) T cells from a HLA-A2(+) donor, but failed to bind to those from a HLA-A2- donor.
De Lau et al. (1992)CD8T cellsThis hybrid hybridoma (quadroma)-produced bsAb binds as a monomeric molecule to CD3+ CD8+ but not CD3+ CD4+ T cells.
Rabinowitz et al. (1997)CD8T cellOur studies show that activation of CD4+ cells per se does not elicit the CD4+CD8+ phenotype and that soluble T cell markers do not bind to T cells.
Zafra et al. (2009)CD8T lymphocytesHLN showed a significant enlargement due to the hyperplasia of lymphoid follicles and infiltration of CD2(+), CD4(+), CD8(+), gammadelta(+) T lymphocytes in both infected groups respect to the uninfected control, with no significant differences between the infected control and immunised group.
Aliahmad and Kaye (2006)CD8T cellsOne of the puzzling features of positive selection is how specificity of the TCR controls lineage commitment, as both helper and cytolytic T cells utilize the same antigen-receptor components, with the exception of the CD4 or CD8 coreceptors themselves.
Sacha et al. (2007)CD8T cellsWe have recently shown that Gag-specific CD8+ T cells recognize simian immunodeficiency virus-infected cells at 2 h postinfection, whereas Env-specific CD8+ T cells do not recognize infected cells until much later in infection.
Pogue et al. (1995)T-cell receptorT-cellPosition 1 (P1) amino acid substitutions were emphasized because P1 alterations may not alter the T-cell receptor interaction.
Sprent et al. (1999)T-cell receptorT-cellIn addition to responding to specific antigen, CD8+ T-cells with a memory (CD44hi) phenotype undergo bystander proliferation when exposed to certain cytokines, notably type I interferons (IFN I), in vivo; such proliferation does not require T-cell receptor ligation.
Spits et al. (1986)T-cell receptorT-cellFurthermore, T-cell receptor and target antigen cannot interact unless there is conjugate formation.
Moore et al. (2009)CD8T cellThese results indicate that functional avidity of a T cell does not necessarily correlate with TCR affinity and CD8-independent antigen recognition by a T cell does not always mean its TCR will transfer CD8-independence to other effector cells.
Böldicke et al. (2000)T-cell receptorT-cellsThis mAb (IgG(1), kappa light chain) bound very specifically to peptide 38 as shown by ELISA but did not recognize the corresponding native Vbeta 6.2 T-cell receptor on T-cells.
Lacoste-Eleaume et al. (1992)T-cell receptorT-cellThese results indicate that the mAb does not recognize the chicken T-cell receptor for
McDermott et al. (1996)T-cell receptorT-cellNo linkage or association of telomeric and centromeric T-cell receptor beta-chain markers with susceptibility to type 1 insulin-dependent diabetes in HLA-DR4 multiplex families.
Gebel et al. (1989)T-cell receptorT cellsT cells from patients successfully treated with OKT3 do not react with the T-cell receptor antibody.