Viewing affirmative mentions of gene expression of IL2 (H. sapiens)

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Levi-Schaffer et al. (1996)IL-2eosinophilsPrevious studies have shown that human peripheral eosinophils respond to IL-2 in chemotaxis and express the IL-2 receptor (CD25).
Bossé et al. (1996)IL-2eosinophilsTo verify the hypothesis that eosinophils produce interleukin-2 (IL-2), a cytokine essential for lymphocyte activation, the expression of IL-2 was examined in peripheral blood eosinophils obtained from normal, atopic, asthmatic and hypereosinophilic subjects.
Bossé et al. (1996)IL-2 mRNAeosinophilsIn-cell RT-PCR combined with in situ hybridization further confirmed that it was the eosinophils that expressed IL-2 mRNA.
Bossé et al. (1996)IL-2eosinophilsThese data, obtained by different techniques, demonstrate that eosinophils can express IL-2.
Rand et al. (1991)interleukin 2eosinophilsHuman eosinophils express functional interleukin 2 receptors.
Plumas et al. (1991)IL2eosinophilThese data provide preliminary evidence for the expression of a low-affinity receptor for IL2 on in vivo activated eosinophils and raise the question of the role played by this cytokine in eosinophil differentiation and activation.
Lissoni et al. (1993)IL-2eosinophilThe increase in lymphocyte, T lymphocyte, natural killer (NK) cell, activated T lymphocyte and eosinophil mean number was significantly higher during IL-3 plus IL-2 than during IL-2 alone.
De Pitá et al. (1997)IL-2eosinophilThe presence of activated T helper cells in lesions and peripheral blood of BP patients, the eosinophilia, the high levels of serum IgE, eosinophil cationic protein and soluble immune products such as IL-2, sIL-2R, IL-5, soluble CD23 (sCD23) strongly suggest the involvement of a cell-mediated immune reaction in which Th2 lymphocytes could play a pivotal role.
Levi-Schaffer et al. (1996)IL-2eosinophilsThese data are consistent with the hypothesis that eosinophils synthesize, release and store IL-2 largely within cystalloid granules.
Bossé et al. (1996)IL-2eosinophilsFinally, IL-2 was detected in purified eosinophils by immunochemistry.
Maleki et al. (2010)IL-2eosinophilThey also showed a decrease in serum levels of sIL-2R, IL-4, IL-5, IgE and eosinophil count.
Rutella et al. (1996)IL-2eosinophilEosinophil peak in peripheral of the eosinophil population showed a high expression of the IL-2 receptor alpha-chain (CD25), representing up to 94% of gated cells.
Kelso and Metcalf (1985)IL-2eosinophilA panel of 55 alloreactive murine T-lymphocyte clones was screened for the production of granulocyte-macrophage colony stimulating factor (GM-CSF), multilineage CSF (multi-CSF), human-active eosinophil CSF (human-active EO-CSF), and interleukin 2 (IL-2) in response to stimulation with the lectin concanavalin A.
Woerly et al. (1999)IL-2eosinophilsThe demonstration that eosinophils from patients could produce IL-5, IL-4 and IL-2 suggested their participation in the regulation of immune response.
Woerly et al. (1999)IL-2eosinophilsWhereas almost 100% eosinophils expressed intracellular IFN-gamma, IL-2 and IL-10, the expression of IL-4, IL-5 and IL-13 is more variable and increased in patients versus donors.
Tabata et al. (1997)IL-2eosinophilThese results suggest that DHEA may be one of the regulators of IgE synthesis and eosinophil proliferation in patients with AD and it may act by controlling IL-4, IL-5 and IL-2 production by lymphocytes.
Woerly et al. (1999)IL-2eosinophilsIn the present work, we have examined the presence of Th1 (IFN-gamma, IL-2) and Th2 (IL-4, IL-5, IL-10 and IL-13) cytokines in eosinophils from patients or donors by intracellular flow cytometry, and by immunocytochemistry.
Simon et al. (2003)IL-2eosinophilWe observed that eosinophils from most patients with hypereosinophilia express the alpha-chain of the IL-2 receptor (CD25), and that IL-2 enhances platelet-activating factor-stimulated release of eosinophil cationic protein from CD25-expressing but not from CD25-negative eosinophils.
Yang and Renzi (1993)IL-2eosinophilHowever, upregulation of the CD25 receptor on normal lymphocytes by incubation with concanavalin A led to the production of IL-2-CM, which did not increase eosinophil proliferation from progenitors.
Czech et al. (1993)IL-2eosinophilCytokine-induced ICAM-1 expression was specific, because IL-1 alpha, IL-1 beta, IL-2, IL-4, IL-6, IL-7, IL-8, C5a, and platelet-activating factor did not significantly affect eosinophil ICAM-1 surface expression.
Wüthrich et al. (1992)IL-2eosinophilic leucocyteLevels of soluble IL-2 receptors, IL-6, soluble CD23, soluble CD14 and ECP (eosinophilic cationic protein) were measured as markers of T-cell, B-cell, monocyte and eosinophilic leucocyte activation in 26 patients with atopic dermatitis (AD) on admission to (A) and at discharge from (D) the Department of Dermatology in Zurich.
Lissoni et al. (1994)IL-2eosinophilsThe mean increase in T lymphocytes, natural killer cells, and eosinophils was significantly higher in patients treated with IL-2 plus MLT than in those who received IL-2 alone.
Kawaguchi et al. (1997)IL-2eosinophilsNeither IL-2 nor IL-4 producing CD4+ cells had any relation to the serum IgE levels and the number of eosinophils in the patients.
Koduru et al. (1995)IL-2eosinophilsIn situ hybridization of interleukin-2 (IL-2) and interleukin-5 (IL-5) cDNA probes on tissue sections identified the synthesis of IL-5 by the eosinophils, suggesting an autocrine pathway of eosinophilopoiesis leading to hypereosinophilia in this patient.
Sakata et al. (1985)lymphokineeosinophilSelective potentiation of eosinophil chemotactic lymphokine production in alum hydroxy gel- and Bordetella pertussis vaccine-treated guinea pigs.
Yamamoto et al. (1997)IL-2eosinophilsCONCLUSIONS: The increased IL-5 and decreased IL-2 production observed with PBMCs from children with atopic dermatitis may underlie the activation of eosinophils and high serum immunoglobulin E concentrations also apparent in such individuals.
Furue et al. (1994)IL-2eosinophilHowever, levels of soluble IL-2 receptor and eosinophil cationic protein seem to parallel to each other in 65% of patients with AD.
Furue et al. (1994)IL-2eosinophilWe found that both soluble IL-2 receptor levels and eosinophil cationic protein levels were significantly higher in atopic dermatitis than in urticaria or normal controls.
Lavigne et al. (1997)cytokines interleukin-2EOSUsing this method, we successfully detected the cytokines interleukin-2 (IL-2), IL-4, IL-5, and interferon gamma (IFN gamma) in blood EOS of normal and hypereosinophilic subjects (n = 12).
Krug et al. (1997)IL-2eosinophilsFirst results reveal interesting new aspects with regard to the expression of IFN-gamma, IL-2, IL-4 and IL-5 in T-cells, and of ECP and EPO in eosinophils in bronchial asthma.
Tashiro et al. (1987)lymphokineeosinophilsSplenic T lymphocytes of complete Freund's adjuvant (CFA)-treated guinea pigs spontaneously produce a lymphokine, eosinophil-directed chemotactic inhibitory factor (ECIF), which selectively inhibits the chemotactic response of the treated eosinophils to a certain chemotactic lymphokine for eosinophils.
Büttner et al. (2003)IL-2eosinophilsBefore each infusion and 12 weeks after the last infusion, peripheral blood leukocytes were examined, qualitative and quantitative distribution of eosinophils and lymphocyte subpopulations, frequencies of IL-2, -3, -4, -5, -10, -13, interferon-gamma-producing CD4 T-cells and serum eosinophil cationic protein (ECP) levels were determined.
Scavuzzo et al. (2005)IL-2eosinophilsWe determined levels of IgE in blood, ECP and cytokines (IL-4, IL-6, IL-8, IFN-gamma and IL-2) in nasal mucus, and number of infiltrating eosinophils in nasal tissue.
Leonardi et al. (1999)IL-2eosinophilLevels of IL-4, IL-2, IFN-gamma, IL-2R, total IgE, eosinophil cationic protein (ECP), eosinophil protein X/neurotoxin (EPX), and myeloperoxidase (MPO) were also evaluated in serum.
Davoine et al. (2004)IL-2eosinophilsMETHODS: First, purified blood eosinophils were incubated with IL-1beta, IL-2, IL-4, IL-5, IL-9 or IL-16, GM-CSF, IFNgamma, eotaxin or 5-oxo-ETE and CD16 expression was measured.
D'Auria et al. (1998)interleukin-2eosinophilEight cytokines (interleukin-2, interleukin-3, interleukin-4, interleukin-5, interleukin-10, tumor necrosis factor-alpha, oncostatin-M and vascular endothelial growth factor), two acute phase reactants (alpha-1 acid glycoprotein, haptoglobin), albumin, one soluble membrane molecule with adhesion functions (sICAM-1) and the eosinophil cathionic protein (ECP) were measured in samples from 15 patients affected with BP by means of commercially available tests.
Kato et al. (2010)IL-2eosinophilMETHODS: We determined peripheral eosinophil count, and the serum levels of ECP and 27 types of cytokines/chemokines (IL-1 beta, IL-1 ra, IL-2, -4, -5, -6, -7, -8, -9, -10, -12, -13, -15 and -17, IFN-gamma, IP-10, TNF-alpha, GM-CSF, G-CSF, MCP-1, MIP-1 alpha and -1 beta, eotaxin, RANTES, PDGF-bb, FGF basic and VEGF) using a multiplex bead-based assay in 85 acute and 79 stable asthma patients, and 14 controls.