Viewing affirmative mentions of gene expression of IL2 (H. sapiens) in dendritic cells

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Silvennoinen et al. (1988)IL-2dendritic cellsAccessory cells differed in their ability to activate T cells presumably depending on their ability to induce IL-2 synthesis, allogeneic dendritic cells being the most effective accessory cells and IL-2 synthesis stimulators.
Hurez et al. (2003)IL-2dendritic cellTo define the basis for restricted IL-2 expression, a videomicroscopic system and IL-2 reporter transgenic model were used to characterize dendritic cell (DC)-T cell interactions.
Barbour and Coventry (2003)interleukin-2dendritic cellCD1a+ putative dendritic cell density and expression of the early lymphocyte activation markers interleukin-2 receptor alpha (IL2Ralpha) and CD69 was low.
Granucci et al. (2003)interleukin 2dendritic cellsThe recent observation that dendritic cells produce interleukin 2 following microbial stimulation opens new possibilities for understanding the efficiency of dendritic cells in regulating immune system functions.
Granucci et al. (2003)interleukin-2dendritic cellsThe immune response is initiated by dendritic cells via interaction with microorganisms and interleukin-2 production.
Granucci et al. (2001)IL-2dendritic cellsInducible IL-2 production by dendritic cells revealed by global gene expression analysis.
Arthur et al. (1997)IL-2DCsIn contrast, AdV vectors expressing luciferase, beta-galactosidase, IL-2, and IL-7 all readily transduced human DCs.
Arthur et al. (1997)IL-2DCsAlthough levels of maximal gene expression in DCs were significantly lower than those obtained using human tumor cell lines, IL-2 and IL-7 production of up to 5 x 10(2) ng/10(6) DC were achieved.
Dietz et al. (2001)interleukin 2dendritic cellsBACKGROUND: We investigated if dendritic cells (DC), derived from patients suffering from chronic myeloid leukemia (CML) could be modified by recombinant replication-defective adenoviruses to express functional interleukin 2 (IL-2).
Granelli-Piperno et al. (1988)IL-2dendritic cellsLikewise in the primary MLR between dendritic cells and T cells, dendritic cells were not impaired following pulsing with CsA, whereas treated T cells made 70% less IL-2.
Jenkins et al. (2001)IL-2dendritic cellOnce stimulated by a dendritic cell, antigen-specific CD4 T cells produce IL-2 but proliferate in an IL-2--independent fashion.
Jonuleit et al. (2000)IL-2DCsThese T cells lost their ability to produce interferon gamma, IL-2, or IL-4 after several stimulations with immature DCs and differentiated into nonproliferating, IL-10-producing T cells.
O'Beirne et al. (2010)IL-2dendritic cellsGPC-3: glypican-3; HCC: hepatocellular carcinoma; PBMC: peripheral blood mononuclear cells; DC: dendritic cells; LPS: Lipopolysaccharide; TIL: tumour infiltrating lymphocytes; IL-2: interleukin 2; TAA: tumour-associated antigens; CTL: cytotoxic T lymphocyte; TAP: transporters associated with antigen processing; IL-4: interleukin-4; eGFP: enhanced green fluorescent protein.
Charrier et al. (2007)interleukin-2dendritic cellsDefects of T-cell proliferation and interleukin-2 production, and the cytoskeletal anomalies in WAS dendritic cells were also corrected.
Hofmann et al. (1986)TCGFdendritic cellsTogether, our experiments suggest that the immune deficiency in AIDS cells may be partially due to a decreased capability of T lymphocytes to produce TCGF and that a decreased number and/or function of dendritic cells may also be involved.
Ahn et al. (2007)IL-2DCsHowever, the reversal of suppression by DCs was not dependent upon the increase of IFN-gamma and IL-2 production or inhibition of IL-10 and/or TGF-beta production.
Zhou and Tedder (1995)IL-2dendritic cellsResting and activated CD83+ dendritic cells also expressed receptors for IL-2 (CD25), TGF-beta 1 and -beta 3, and GM-CSF as determined by indirect immunofluorescence staining.
Megiovanni et al. (2004)IL-2DCsThe ability of purified protein derivative-loaded DCs to stimulate autologous T cells to produce IL-2, IL-4 and interferon-gamma indeed depended on their activation stage and endocytic activity, which decreased upon maturation.
Li et al. (2009)IL-2DCsCONCLUSIONS: SLC and IL-2 were produced by autocrine in DCs transfected with SLC and IL-2 genes.
Li et al. (2009)IL-2DCsRESULTS: A high level of expression of SLC and IL-2 was observed in DCs transfected with SLC and IL-2 genes.
Li et al. (2009)IL-2DCsDCs were transfected with pBudCE4.1/SLC-IL-2 by gene electric transfection.
Ellis et al. (1991)IL2dendritic cellsThese findings therefore demonstrate the role of dendritic cells as potent in vitro inducers of IL3, IL4 and IFN-gamma synthesis as well as of IL2.
Li et al. (2007)interleukin-2 genedendritic cell[Co-expression of HSV-1 gD gene and interleukin-2 gene in dendritic cell].
Tarhini and Iqbal (2010)IL-2dendritic cellsThese patients had been previously vaccinated with either irradiated autologous GMCSF-secreting tumor cells or with autologous dendritic cells made to express gp100 peptide and IL-2 or with gp100 and MART-1 peptides.
Muraille et al. (1995)IL-2dendritic cellsBy stimulating naive T cells in the presence of graded doses of superantigens, we have observed that half-maximal IL-2 production was achieved at lower doses of superantigens in the presence of dendritic cells.
Xu et al. (2008)IL-2dendritic cellsTheir effector function was demonstrated in vitro upon MART-1 peptide stimulation (in the presence of APC such as dendritic cells) using methods such as cytokine production (IL-2, GM-CSF, IFN?)
Brivio et al. (2000)interleukin-2dendritic cellsSince surgery-induced immunosuppression has been proven to be associated with a decline in the blood levels of both interleukin-2 and interleukin-12, it could depend at least in part on a transient deficiency of dendritic cells system.
Shigematsu et al. (2007)IL-2DCsThe 0.05Gy-irradiation does not augment the expression of major histocompatibility complexes (MHCs) or costimulatory molecules on DCs, as with non-irradiated DCs or 1Gy-irradiated DCs, but does augment the production of IL-2, IL-12 and IFN-gamma DCs.
Dupont and Craciun (2009)IL-2DCsA state of antigen-specific tolerance is induced by induction of Treg cells, inhibition of DCs, which remain at a an immature state, inhibition of production of the proinflammatory cytokines IL-2, IFN-gamma, TNF-alpha and IL-12, and induction of production of cytokines IL-10, TGF-beta and IL-1Ra.
Papagno et al. (2004)T-cellDCsThe potential relationship between T-cell activation and differentiation was first studied using a system of in vitro priming of naïve CD8+ T-cells by dendritic cells (DCs), which represents a useful model to analyse the generation of antigen-experienced CD8+ T-cells.
Sturlan et al. (2009)IL-2dendritic cellsproduction by NK cells was possible by co-cultivation with dendritic cells producing IL-12 or with CD3+ cells producing IL-2, respectively.
Rogers et al. (2005)IL-2dendritic cellsHere, we demonstrate that the beta-glucan receptor Dectin-1, a yeast binding C type lectin known to synergize with TLR2 to induce TNF alpha and IL-12, can also promote synthesis of IL-2 and IL-10 through phosphorylation of the membrane proximal tyrosine in the cytoplasmic domain and recruitment of Syk kinase. syk-/- dendritic cells (DCs) do not make IL-10 or IL-2 upon yeast stimulation but produce IL-12, indicating that the Dectin-1/Syk and Dectin-1/TLR2 pathways can operate independently.
Li et al. (2003)IL-2DCsThe peripheral blood mononuclear cells (PBMCs) isolated from those subjects were stimulated with HBcAg 18 to 27 CTL epitope peptide, and intracellular cytokine staining (ICCS) was used for detecting IFN-gamma, IL-2 and TNF-alpha produced by CD8+ T cell. (2) DCs generated from PBMCs were pulsed with HBcAg 18 to 27 CTL epitope peptide, then were cocultured with autologous lymphocytes for 10 days to induce antigen-specific T cell, which was assessed by ICCS and cytotoxic assay.
Yamazaki et al. (2003)IL-2DCsCD25+ CD4+ T cell growth requires DC-T cell contact and is partially dependent upon the production of small amounts of IL-2 by the T cells and B7 costimulation by the DCs.
Kawamura et al. (2003)IL-2dendritic cellsDecreased stimulation of CD4+ T cell proliferation and IL-2 production by highly enriched populations of HIV-infected dendritic cells.
Goodridge et al. (2007)IL-2dendritic cellsFurthermore, we show that NFAT activation regulates IL-2, IL-10 and IL-12 p70 production by zymosan-stimulated dendritic cells.
Kandler et al. (2006)IL-2DCsExposure of DCs to LL-37 during LPS exposure induced co-cultured naive T cells to produce less IL-2 and IFN-gamma and decreased their proliferation.
LeibundGut-Landmann et al. (2007)IL-2DCsThe C-type lectin dectin-1 binds to yeast and signals through the kinase Syk and the adaptor CARD9 to induce production of interleukin 10 (IL-10) and IL-2 in dendritic cells (DCs).
Cho et al. (2009)IL-2DCsDCs themselves also produce many cytokines including interferon-gamma and interleukin (IL-2) to kill the tumor cells.
Peng et al. (2004)IL-2DCsBoth vectors induced IL-12 and TNF-alpha, but only Lm-LLO-E7 induced IL-2 production by DCs.
Xu et al. (2009)IL-2DCsFurthermore, betamD-treated DCs have significantly attenuated production of IL-2, IL-10, and TNFalpha upon Dectin-1 engagement, and they also exhibit impaired phagocytosis of zymosan particles.
Lilleri et al. (2008)interleukin-2dendritic cellsMETHODS: The membrane phenotype (CCR7 and CD45RA expression) of and intracellular cytokine (interferon [IFN]-gamma and interleukin-2) production by HCMV-specific T cells (stimulated with HCMV-infected dendritic cells) were investigated in 21 immunocompetent pregnant women (12 transmitters and 9 nontransmitters) and in 5 nonpregnant subjects during the first year after infection.