Viewing affirmative mentions of gene expression of cd3g (X. laevis) in T cells

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Wallentine et al. (2009)CD3T-cellHowever, the expression of the lineage-specific T-cell antigen, CD3, in hematologic malignancies is exceedingly rare and to the best of our knowledge has not been reported in pediatric patients.
Tse and Liang (2004)CD3T-cellAll NK tumor cells express the NK cell marker CD56, but they lack the expression of surface CD3 and the rearrangement of T-cell receptor genes, which distinguish them from T-lymphoid neoplasms.
Dietl et al. (1990)CD3T cellsIn the present study we applied the immunohistochemical ABC method to investigate the expression of CD3, TCR alpha/beta and TCR gamma/delta molecules on intradecidual T cells with a panel of mAbs.
Dietl et al. (1990)CD3T cellsWhereas intradecidual T cells expressed readily detectable amounts of CD3, they lacked immunohistochemically detectable amounts of either alpha/beta or gamma/delta TCR heterodimers on their cell surface.
Venet et al. (2005)CD3T lymphocytesBoth percentage of gammadelta T lymphocytes and CD3 expression are reduced during septic shock.
Venet et al. (2005)CD3T lymphocytesThe objective of the present study was to investigate whether two characteristics of T cells were altered in this situation: the percentage of circulating gammadelta T lymphocytes and the level of CD3 expression on T lymphocytes.
Angermeier et al. (1987)CD3T-cellsBecause the perinuclear space is reported to be a site of protein synthesis in cells with little ER, and because of the occasional ER staining observed in cells with perinuclear staining, perinuclear CD3 positivity probably represents CD3 synthesis in mature tonsillar T-cells.
Angermeier et al. (1987)CD3T-cellThe frequency of perinuclear positivity in the FCC-associated T-cells, together with the loss of surface positivity in some cells at this site, suggests that this could represent in vivo T-cell "activation" in follicular centers, with modulation and resynthesis of the CD3 antigen.
Mezzetti et al. (1991)CD3T cellsHuman bronchial epithelial cells modulate CD3 and mitogen-induced DNA synthesis in T cells but function poorly as antigen-presenting cells compared to pulmonary macrophages.
Meliconi et al. (1992)CD3T-lymphocytesThe distribution of T-lymphocytes expressing CD3 and T-cell receptor gamma-delta (T gamma/delta) has been examined by immunocytochemistry in the synovial membrane of eight patients with inflammatory arthritis (six rheumatoid arthritis, two spondyloarthritis) and eight with non-inflammatory arthritis (four osteoarthritis, four post-traumatic arthritis).
Zhang et al. (2009)CD3T cellsT cells coexpressing CD3 and CD10 are a characteristic feature of angioimmunoblastic T-cell lymphoma (AITL) [1].
Bauer et al. (1996)CD3T-cellsAt autopsy, immunopathological studies of small intestines and colon specimens showed a clonal expansion of morphologically normal T-cells in the intestinal mucosa, which expressed the abnormal phenotype CD2+CD3+CD4-CD5-CD8-.
McKay et al. (1991)CD3T cellsAlthough most circulating T cells in normal subjects express both CD3 and CD5 antigens on the cell surface, a small number lack the CD5 antigen.
Tunnacliffe et al. (1988)CD3T cellCD3 gene expression is one of the first events during the maturation of the thymocyte, and therefore the clustering of CD3 genes may define a chromatin domain which is activated early in T cell development.
Sanz et al. (2010)CD3T-cellImmunohistochemistry was positive for CD3, consistent with epitheliotropic T-cell lymphoma.
Pye et al. (2000)CD3T-cellImmunohistochemical analysis revealed that the small well-differentiated lymphocytes labeled for the anti-human T-cell marker, CD3, and the large anaplastic round cells labeled with the anti-human B-cell marker, CD79a.
Lee et al. (2010)CD3T cellIntracellular cytokine expression of CD3(+)CD4(+) and CD3(+)CD8(+) cells, and Th1/Th2 cytokine-producing T cell ratios were determined using flow cytometric analysis.
Taniwaki et al. (1990)CD3T cellWhen the patients were divided into two groups depending on the expression of a mature antigen of T cell lineage, CD3, two with CD3+ phenotype had a stable disease, whereas three of the four patients with CD3- phenotype had marked hepatosplenomegaly and a highly aggressive disease.
Crosbie et al. (1998)CD3T-lymphocytesT-lymphocytes maintain a high level of activation following liver transplantation and continue to express high levels of the surface marker CD3, which may account for the occurrence of acute cellular rejection despite immunosuppression in these patients.
Chao et al. (1995)CD3T cell(Am J Reprod Immunol 1993;29:1-4) found that all early intradecidual CD3+ T cells expressed either T cell receptor (TCR) alpha/beta or gamma/delta but that the expression of the CD3+/TCR complex was down-regulated.
Chao et al. (1995)CD3T cellsRESULTS: Intradecidual CD3+ T cells expressed either TCR alpha/beta or gamma/delta, and the level of expression of the CD3/TCR complex was down-regulated in normal pregnancy, anembryonic pregnancy, and recurrent spontaneous abortion.
Wood et al. (1993)CD3T-cellHeterogeneity of CD3 antigen expression in T-cell lymphoma.
Wood et al. (1993)CD3T-cellCD3 antigen expression was studied in a series of 98 T-cell lymphomas, using polyclonal antibodies which recognize this molecule in routinely processed, paraffin-embedded, tissue.
Wood et al. (1993)CD3T-cellThis phenomenon of heterogeneous CD3 expression was commonest in pleomorphic T-cell lymphomas (22/42 cases) and in CD30 (Ki-1)-positive lymphomas (5/11 cases), and was less frequently observed in mycosis fungoides (4/18 cases) and not seen in T-cell lymphoblastic lymphoma (0/9 cases).
Lambert and Genin (2004)CD3T cellsCD3 overexpression on gammadelta T cells was confirmed by a combination of monoclonal antibody staining (CD3-ECD, gammadeltaTCR-FITC, and alphabetaTCR-PE-Cy5) or immunomagnetic purification of gammadelta T cells (i.e., MdFI 20 vs 8.86).
Engelmann et al. (2006)CD3T cellsHuman leucocyte antigen-DR was expressed on a lower percentage of cord compared to maternal gammadelta and CD3(+) T cells.
Bassan et al. (1988)CD3T-cellIn these cases, LGLs expressed the phenotype of CD3+ NK and CD3- NK cells, respectively, and were clonal in the first patient as demonstrated by T-cell receptor gene rearrangement study.
Ledbetter et al. (1988)CD3T cellsThe CD3/CD4 heteroconjugate also shows significantly greater activity in stimulation of inositol phosphate IP1, IP2 and IP3 synthesis in T cells than the CD3 mAb alone, and again the activity is inhibited by free CD4 mAb.
Ledbetter et al. (1988)CD3T cellsThe binding of antibody to the CD4 molecule inhibits mobilization of cytoplasmic free calcium ([Ca2+]i) in response to CD3 cross-linking on resting T cells.
Venet et al. (2005)CD3T-cellThe magnitude in the decrease of CD3 expression was thus similar in alphabeta and gammadelta cells, suggesting a common down-regulation mechanism for both T-cell lineages.
Venet et al. (2005)CD3T cellsCONCLUSIONS: Combined with a reduced percentage of monocytes expressing human leukocyte antigen-DR, a reduced CD3 expression may be involved in the failure of antigen presentation depicted after septic shock, whereas the diminished percentage of circulating gammadelta T cells could be partly responsible for the elevated incidence of secondary infections.
Matis et al. (1987)CD3T-cellHere we describe an alloreactive CD3+CD4-CD8-TCR gamma delta-expressing, TCR alpha beta-negative, T-cell line that manifests MHC-linked recognition specificity for both proliferation and cytotoxicity.
Hĺkelien et al. (2005)CD3T cellsAdditionally, growth of cells in suspended aggregates, expression of CD3 and CD28 T cell surface markers, and interleukin-2 secretion by 293T cells treated with extract of adult peripheral blood T cells illustrate a functional nuclear reprogramming.
Camera et al. (2000)CD3T-lymphocytesBACKGROUND AND OBJECTIVE: Large granular lymphocytes derive from two major lineages: one expressing the CD3 surface antigen (T-lymphocytes), and the other lacking this marker (NK-cells).
Chu et al. (1990)CD3T cellThe cells from all 5 T cell clones detected for indirect fluorescence expressed CD3 and CD4 surface markers.
Kojima et al. (1992)CD3T-cellThe tumor was histologically shown to be of diffuse large cell type, and phenotypic analysis revealed high expression of CD3 and CD4, indicative of a helper/inducer type of T-cell lymphoma.
Angermeier et al. (1987)CD3T-cellBecause the functional role of these cells remains imprecisely determined and because ultrastructural localization of the T-cell antigen receptor-associated CD3 antigen has not been previously reported, an immunoultrastructural study of four tonsils and four FCC lymphomas was performed using an anti-CD3 antibody (UCHT-1).
Arnaiz-Villena et al. (1993)CD3T lymphocytesThe absence of CD3 gamma did not prevent the expression of certain amounts of TCR/CD3 complexes on the surface of T lymphocytes.
Kim et al. (1999)CD3T-cellRenal graft biopsy performed 58 days posttransplantation showed extensive interstitial infiltrates of polymorphic lymphoid cells, which expressed the UCHL-1 and CD3 markers for T-cell lineage.
Zimmer et al. (1998)gamma/delta-TCRT lymphocytesCD8, alpha/beta-TCR, and gamma/delta-TCR were found in vacuoles and Golgi complexes within these gliadin-containing enterocytes in addition to the surface of intraepithelial and mucosal T lymphocytes.
van der Harst et al. (1991)gamma deltaT-cellAnalysis of the V gamma and V delta usage at the clonal level confirmed the observation that early after BMT only V gamma 9+V delta 2+ cells are present, whereas gamma delta T-cell clones expressing other gamma delta TCR phenotypes can only be detected 4 to 6 weeks post-BMT.
Matsuda et al. (1994)CD3T-cellThe role of protein kinase C (PKC) system on CD3 expression on adult T-cell leukaemia (ATL) was examined.
Matsuda et al. (1994)CD3T cellsCulture with H-7 of HTLV-1 transformed T cells, ATL-2 cells whose CD3 expression had been decreased, led to enhancement of CD3 expression in a time-dependent manner.
Ginaldi et al. (1996)CD3T-cellDifferential expression of CD3 and CD7 in T-cell malignancies: a quantitative study by flow cytometry.
Ginaldi et al. (1996)CD3T-cellWe have addressed this problem by comparing the levels of expression of CD3 and CD7 on T lymphocytes from 18 healthy donors with those of 61 cases of T-cell leukaemia using quantitative flow cytometry with a method that converts fluorescence intensity into number of antigen molecules per cell.
Matis et al. (1987)TCR gamma deltaT cellsOur results suggest that T cells expressing TCR gamma delta are capable of self-non-self MHC discrimination and that they can undergo MHC-influenced selection during differentiation like TCR alpha beta-expressing T cells.
Cibull et al. (1989)CD3T-cellIt therefore appears that some Hodgkin and Reed-Sternberg cells can express the major T-cell antigen CD3.
Arnaud et al. (2001)CD3T cellsIn addition, TCR/CD3 hexamers and zeta2 homodimers colocalize in normal Jurkat T cells, in revertant J79r58 cells, and in J79 cells transfected with wild-type TCRalpha cDNA but not in J79 mutant cells (confocal microscopy).
Crosbie et al. (1998)CD3T cellStable transplant patients (n=11) had a significantly higher level of activation (HLA-DR expression ) of all T cell subsets: CD3, CD4 and CD8 compared to healthy controls: 17.5% +/- 14.0 (mean +/- SD) vs 4.7 +/- 1.8 (p=0.04), 13.7% +/- 10.3 vs 4.3 +/- 1.7 (p=0.03) and 23.8% +/- 19.9 vs 3.6 +/- 2.4 (p=0.02) respectively.
Chan et al. (2004)CD3T cellsRPP microarrays were used to profile the phosphorylation state of 62 signaling components in Jurkat T cells stimulated through their membrane CD3 and CD28 receptors, identifying a previously unrecognized link between CD3 crosslinking and dephosphorylation of Raf-1 at Ser259.
Matsuda et al. (1993)CD3T lymphocytesImmunological abnormality of T lymphocytes in patients with adult T cell leukemia (ATL) is characterized by abnormal expression of the 55 kD chain of the receptor for interleukin 2 (IL-2R/p55) (Tac), and the down-regulation of CD3 expression.
June et al. (1986)CD3T cellsOur results support the concept that CD2 represents the trigger for a distinct pathway of activation both for T cells that express the CD3 molecular complex and for large granular lymphocytes that do not.
Park et al. (2008)CD3T cellsIn a study of children in Canada, Dales (1998) reported a significant association between living in fungal-contaminated homes with higher airborne ergosterol levels and an increased number of CD3+ T cells expressing CD45RO.
Matis et al. (1987)CD3T-cellSeveral recent studies have identified a distinct subset of CD3(T3)+CD4-CD8-T lymphocytes that express a CD3-associated heterodimer made up of the protein encoded by the T-cell receptor (TCR) gamma-gene and a second glycoprotein termed TCR delta (refs 1-4).
Lara et al. (2006)CD3T cellsOnce the labeling protocol was optimized, the MiniMACS system performed well by producing a highly enriched CD3(+) fraction, and a respectable level of depletion of T cells and recovery of KG1a cells in the depleted fraction; an average log(10) depletion of T cells of 2.88 +/- 0.17 and an average recovery of the KG1a cells of 60.8 +/- 5.94% (n = 14).
Hellstrand and Hermodsson (1993)CD3T-cellBy contrast, T-cell proliferation and the expression of CD3 on CD56- T cells were not susceptible to cell contact-mediated suppression by monocytes.
Morii et al. (1993)CD3T cellPROBLEM: Dietl et al. considered "intradecidual T cell tolerance towards fetal antigens" with their observation that intradecidual T cells lack immunohistochemically detectable amounts of T cell receptor (TCR) molecules while expressing normal amounts of CD3 molecules during early normal pregnancy (Am J Reprod Immunol. 1990; 24:33-36).
Lanier and Weiss (1986)CD3T cellsPreliminary studies suggested that T cells expressing CD3 but lacking Ti are present in low frequency in normal lymphoid tissues.
van de Griend et al. (1987)CD3T cellSuch CD3+ T cell clones do not express the CD16 (IgG Fc receptor) antigen, but as we demonstrate here, the CD16 antigen can be identified on CD3+4-8-clones.
Shivnan et al. (1992)CD3T cellDoes co-aggregation of the CD45 and CD3 antigens inhibit T cell antigen receptor complex-mediated activation of phospholipase C and protein kinase C?
Suzushima et al. (1991)CD3T-cellCell surface expression of the T-cell receptor (TCR)/CD3 complex on the cells from 11 acute type adult T-cell leukemia (ATL) and 4 lymphoma type ATL patients was examined by flow cytometry.
Mao et al. (2004)CD3T cells[Regulation of CD3, CD4 and CD8 expressions on PMA-activated human peripheral T cells].
Mao et al. (2004)CD3T-lymphocytesOBJECTIVE: To investigate the effect of mitogen Phorbol 12-myristate 13-Acetate (PMA) on CD3, CD4 and CD8 expression of human T-lymphocytes.
Davis et al. (1989)CD3T cellsDespite rapid modulation of 38.1, the T cells continued to express substantial amounts of surface CD3, suggesting there is a rapid rate of turnover of CD3 molecules on resting T cells.
O'Leary et al. (1988)CD3T cellSeveral studies of T cell-associated surface marker expression in older subjects "with no evidence of diseases known to affect immune function" have suggested that diminished expression of the constant portion (CD3) of the human T cell antigen-receptor complex (CD3/Ti) may be associated with aging.
O'Leary et al. (1988)CD3T cellThese cells represent about 5-6% of the total T cell population in the young and healthy older group and are known to express CD3 in combination with Ti gamma-delta dimers.
O'Leary et al. (1988)CD3T cellsWe conclude that significant quantitative reduction in expression of the CD3/Ti antigen-receptor complex on human T cells is not a feature of the primary aging process and cannot account for diminished in vitro proliferative response of healthy subjects with age.
Sakai et al. (1996)CD3T-cellWe report a case of Sézary syndrome who developed multiple skin tumors that showed transformation, loss of multiple pan T-cell markers (CD3, 4, 5, 7, 8), and a concomitant expression of CD30 during the course of the disease.
van der Harst et al. (1991)gamma deltaT cellsThe large majority of early posttransplant gamma delta and alpha beta T cells express the CD45RO antigen, which is usually expressed on "memory" cells only.
Alvarez-Vallina et al. (1993)CD3T cellDelimitation of the proliferative stages in the human thymus indicates that cell expansion occurs before the expression of CD3 (T cell receptor).
Hara et al. (1991)CD3T-cellAutologous non-T-cell stimulation of the T-cell clones resulted in a decrease in cell surface expression of CD4, whereas the expression of CD2, CD3, and WT31 was unchanged.
Gebel et al. (1989)CD3T lymphocytesUsing a monoclonal antibody against a different CD3 epitope, we detected CD3 expression on T lymphocytes from 18/18 OKT3-treated patients.
van Oostveen et al. (1992)TcR-gamma deltaT-lymphocytesAnalysis of peripheral blood mononuclear cells (PBMC) demonstrated an unusual large proportion of CD3+ T-lymphocytes expressing a gamma delta T-cell receptor (TcR-gamma delta).
Zijenah et al. (2005)CD3T lymphocytesThe %CD4 expressed among lymphocytes and not the %CD4 expressed among CD3+ T lymphocytes is recommended for decision making to initiate ARV therapy in children under the age of 18 months [5].
Scudeletti et al. (1999)CD3PBLWe have analyzed whether GCH are able to affect the expression of the TCR-associated molecules CD3, CD4, and CD8 on PBL-PHA, and whether the modulation of those receptors is related to the GCH-driven apoptosis of the PBL-PHA.
Scudeletti et al. (1999)CD3T cellsPDN, at a pharmacological concentration (10(-6) M), was able to inhibit the CD3 expression on T cells.
Scudeletti et al. (1999)CD3PBLThe inhibition of CD3 is not related to a transcriptional or posttranscriptional phenomenon, because both PBL-PHA and PBL-PHA-PDN expressed the same amount of intracytoplasmic CD3 molecule.
Gessain et al. (1990)CD3T cellsMost of these long-term interleukin-2-dependent cell lines exhibited a pattern characteristic of CD4(+)-activated T cells with high expression of CD2, CD3 and CD4 antigens, associated with a strong density of TAC and DR molecules.
Cremon et al. (2009)CD3T cellsCompared to male IBS patients, female IBS patients had greater numbers of mast cells (P=0.066), but lower numbers of CD3+ and CD8+ T cells (P=0.002 and <0.001, respectively).
Carreno et al. (1990)CD3T cellsDuring phase III, serum of the 4 affected patients could transfer a blocking effect on the expression of the CD3 marker of peripheral blood T cells of "normal" laboratory volunteers.
Suzushima et al. (1991)CD3T-cellDiscordant gene and surface expression of the T-cell receptor/CD3 complex in adult T-cell leukemia cells.
Le Deist et al. (1991)CD3T cellImmunodeficiency with low expression of the T cell receptor/CD3 complex.
Le Deist et al. (1991)CD3T lymphocytesWe report the consequences of low expression of the T cell receptor (TcR)/CD3 complex by T lymphocytes from a 4-year-old boy with a mild immunodeficiency.
Le Deist et al. (1991)CD3T cellsTcR/CD3 expression was found to be deficient on both resting and activated T cells, using both anti-CD3 and anti-TcR alpha/beta monoclonal antibodies.
van Oostveen et al. (1992)TcR-gamma deltaT-cellsImmunofluorescence (IF) stainings with subset-specific monoclonal antibodies showed a fluctuating expansion of TcR-gamma delta+ T-cells expressing V gamma 9 and V delta 2 variable (V) gene segments.
Ginaldi et al. (1996)CD3T lymphocytesNormal T lymphocytes expressed 124 +/- 25 CD3 and 20 +/- 3 x 10(3) CD7 molecules per cell.
Cotta et al. (2006)CD3T-cellMF usually expresses CD3 and CD4 (T-cell) markers.
Ebert (2003)CD3T cellsCD3 expression on IELs, but not PB CD8+ T cells, declined upon activation, due partly to incomplete reexpression after modulation.
Nicolas et al. (2001)CD3T cellsThe aim of our study was to compare CD3 expression on gammadelta T cells and alphabeta T cells in human patients.
Nishii et al. (2000)CD3T cellsThis report details the effects of cyclosporin A (Cs-A) on the clinical course of B-cell chronic lymphocytic leukemia (B-CLL) with an increase in circulating T cells that express CD3, CD8, CD25, CD45RO, and T-cell receptor alpha beta chain.
Patey-Mariaud De Serre et al. (2000)CD3cT-lymphocytesAIMS: We recently showed that refractory sprue is distinct from coeliac disease, the former being characterized by abnormal intraepithelial T-lymphocytes expressing a cytoplasmic CD3 chain (CD3c), lacking CD3 and CD8 surface expression, and showing TCRgamma gene rearrangements.
Geisler (1992)CD3-gammaT cellTransfection of the wild-type CD3-gamma gene into JGN reconstituted expression of functional Ti/CD3 complexes, and analysis of T cell lines producing different amounts of CD3-gamma indicated that CD3-gamma and CD3-delta competed for the binding to CD3-epsilon.