Viewing affirmative mentions of gene expression of ighm (D. rerio) in T cells

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Lin et al. (1985)IgMT lymphocytesT lymphocytes of the AIDS patients showed a consistently greater ability to suppress immunoglobulin M (IgM) synthesis by pokeweed mitogen stimulated allogeneic lymphocytes compared to controls (p less than 0.03).
Mangan et al. (1983)IgMT cellsIgM antibody production induced by F. nucleatum was enhanced by the addition of T cells.
Piessens et al. (1985)immunoglobulinT cellTo investigate the pathogenesis of macroglobulinemia in the tropical splenomegaly syndrome (TSS), we assessed the functional activity of B lymphocytes and T cell subsets in a pokeweed mitogen-driven assay of immunoglobulin synthesis.
Tsuji et al. (2002)IgMT cellsThese findings overturn three widely accepted immune response paradigms by showing that (a) specific IgM antibodies are required to initiate CS, which is a classical model of T cell immunity thought exclusively due to T cells, (b) CS priming induces production of specific IgM antibodies within 1 d, although primary antibody responses typically begin by day 4, and (c) B-1 cells produce the 1-d IgM response to CS priming, although these cells generally are thought to be nonresponsive to antigenic stimulation.
Smith (1984)IgMT-cellThe terminal three sugar residues define their antigenic specificity; they attach to specific receptors on mammalian cells; they exhibit pyrogenicity in rabbits and clot Limulus lysate; they stimulate the production of IgM antibody both in vivo and in vitro; they modulate the immune response to T-cell dependent antigens; they exhibit immunosuppressive and immunostimulatory activities.
Banciu et al. (1990)IgMT lymphocyteImmunologically, the transfer of IgM towards increased IgM, the decrease of the total T lymphocyte and of T1 substrate, the increase of the active B and T lymphocyte.
Krakauer et al. (1981)IgMT cellsAt 4 x 10(5) T cells to 3 x 10(5) allogeneic normal B cells per milliliter, T cells from patients with PSS induce significantly more IgM synthesis by normal B cells than do normal T cells.
Morito et al. (1980)IgMT cellsWhen purified patient and normal T cells were added to B cells in various autologous or allogeneic combinations, it was observed that immunodeficient T cells (AT) from four patients suppressed normal IgM synthesis.
Morito et al. (1980)IgMT cellsIn two patients, autologous T cells were able to help autologous B-cell IgM synthesis in vitro.
Nouri-Aria et al. (1985)IgMT cellTo evaluate the mechanisms underlying the increase in serum IgM in primary biliary cirrhosis (PBC) studies were designed to examine IgM production in vitro and to assess the relative contribution of intrinsic B cell activity and immunoregulatory T cell balance to IgM synthesis.
Wang et al. (1993)IgMT cellsIn contrast, when ROH was preincubated with cord blood T cells, washed and added to the B cell-enriched fraction with SAC, no increase (0.9-1.8-fold) in IgM synthesis was obtained.
Fawcett et al. (1988)IgMT cellsThe abnormality in IgM production in patients with RA was shown to reside in the RA T cell population (p less than 0.005), and RA B cells combined with normal T cells behaved similarly to autologous cultures of normal B and T cells.
Leung et al. (1983)immunoglobulinT cellIn the present study, the possible role of the immunoregulatory T cell abnormalities in the polyclonal B cell activation was investigated by assaying the ability of T cells and T cell factors from patients with acute MCLS to induce immunoglobulin production by normal B lymphocytes.
Etzioni et al. (1987)IgMT-cellImmunological studies in children with type I diabetes mellitus and their healthy relatives: in vitro antigen stimulated IgM production, T-cell subsets and islet-cell antibodies.
Etzioni et al. (1987)IgMT-cellWe have looked at immunoregulatory T-cell subsets autoantibodies and in vitro IgM production in IDDM patients and their healthy first degree relatives.
Andrew and Titus (2001)IgMT cellsBecause some T cells have receptors for IgM, it may be desirable to produce fragments of IgM for both cytotoxicity studies and for in vivo use.
Korsmeyer et al. (1982)IgMT cellNone of the nine marrow recipients between 2 and 15 months after transplantation produced normal amounts of IgG, IgA, or IgM in response to pokeweed mitogen (a T cell-dependent activator).
Korsmeyer et al. (1982)immunoglobulinT cellsThese suppressor cells frequently had profound activity (greater than 80% suppression of the immunoglobulin synthesis of cocultured normal cells), were predominantly radioresistant, and were T cells in the cases where analyzed.
Krantman et al. (1980)IgMT cellsNormal B cells produced IgM, G and A when cultured with normal T cells.
Kramer et al. (1988)IgT cellsWhen UC patients' T cells were co-cultured with normal adults' B cells, Ig synthesis was significantly decreased as compared with normal controls.
Kramer et al. (1988)immunoglobulinT cellsT cells from UC patients significantly decreased immunoglobulin production by control B and T cells (IgM and IgA, p = 0.02; IgG, p = 0.01).
Griesinger et al. (1990)IgT cellsHowever, normal donor T cells did not restore Ig synthesis by B cells of HD patients.
Lum et al. (1982)immunoglobulinT cellsT cells from all 20 normal individuals expressed help and none suppressed immunoglobulin production.
Goddard et al. (1991)IgMT cellThis report describes a fourteen year old girl with an unusual immunodeficiency characterized by persistent lymphadenopathy and associated with hypogammaglobulinaemia, excessive IgM production and a severe T cell defect.
Minegishi et al. (1984)IgMT-cellIn two patients with hypogammaglobulinemia with IgM production, T-cell subsets were normal in distribution and the patients' B cells produced only IgM in culture with autologous T cells.
Crawford et al. (1989)immunoglobulinT-lymphocyteThe consequences of aging of the immune system include impaired T-lymphocyte responsiveness and aberrant immunoglobulin production.
Crawford et al. (1989)immunoglobulinT cellsNo significant age differences were present in initial lymphocyte counts, percent B cells, T cells or monocytes, or helper/suppressor ratios to explain this enhancement in immunoglobulin production.
Singh and Goel (2000)immunoglobulin MT cellsFifty patients of bone and joint tuberculosis (age 15-70 years) and 30 healthy controls were studied for levels of immunoglobulin G (IgG), immunoglobulin A (IgA), immunoglobulin M (IgM), T cells and circulating immune complexes (CICs) in different stages of disease.
Rozynska et al. (1989)IgMT cellT cell help for IgM production is also deficient in CVH, and T cell help in XLA is also abnormal for both IgG and IgM.
Teodorczyk-Injeyan et al. (1986)immunoglobulinT-cellThese alterations in mitogen-induced immunoglobulin production were well correlated with changes in the T-cell alloreactivity in the MLR.
Hedfors et al. (1983)immunoglobulinT-cellIt is concluded that nonspecific stress changes the composition of T-lymphocyte subsets with depression of T-cell stimulation and T-cell-dependent immunoglobulin production.
Goldstein et al. (1987)IgMT cellIrradiation (1000 rads) of the T cell-enriched subpopulation, either with or without Leu-2 positive cell depletion, resulted in statistically significant decreases in IgM and IgM RF production in response to SAC in reconstituted autologous cultures, providing further evidence of a Leu-2 negative radiosensitive sheep-cell rosetting cell active in in vitro SAC responses.
Kato et al. (1993)IgT cellsImprovement of serum Ig levels was observed in the patients in whom Ig production of non-T cells at the first examination and C mu gene expression had been detected to a slight degree, but serum Ig levels remained low in the patients in whom Ig production of non-T cells and C mu gene expression had not been detected.
Romagnani et al. (1983)IgMT lymphocytesSynthesis of both IgM and IgG induced by pokeweed mitogen remained subnormal after addition to patient B cell cultures of autologous irradiated T cells or allogeneic normal T lymphocytes.
Romagnani et al. (1983)immunoglobulinT cellsT cells from patients with Hodgkin's disease appeared at least as effective as normal T cells in helping pokeweed mitogen-induced immunoglobulin production by normal B cells.
Romagnani et al. (1983)immunoglobulinT cellIn patients showing depression of pokeweed mitogen-induced immunoglobulin synthesis the lymphoproliferative response and immunoglobulin synthesis stimulated by Staphylococcus aureus bacteria of the Cowan first strain, a T cell independent B cell mitogen, were also markedly reduced.
Pascual-Salcedo et al. (1983)IgMT cellsEven when patients' B cells were cocultured with normal T cells, IgM production did not reach normal levels.
Pascual-Salcedo et al. (1983)IgT cellsSimilar numbers of these T cells did not suppress Ig production by normal T plus B cells.
Hoffman et al. (1984)IgMT lymphocytesVillagers with tropical splenomegaly syndrome had markedly elevated levels of total IgM, higher titers of IgM antibodies to Plasmodium vivax, and reduced levels of circulating T lymphocytes.
Scornik et al. (1994)IgMT cellThe results showed that when the T cell crossmatch was negative by FC it was always negative by CDC, and that when the T cell results were positive by CDC (IgM antibodies excluded) they were also positive by FC.
De la Concha et al. (1982)IgMT cellsPatients' T cells did not show excess suppressor function in vitro but had a decreased helper activity for IgM, IgG and IgA production.
Ballow et al. (1996)IgMT cellsHighly purified T cells from CBMC, when preincubated for 36 hr with RA, enhanced IgM synthesis of cord blood B cells.
Wang et al. (1983)immunoglobulinT-cellThe two groups differed in measurements of T-cell subsets and immunoglobulin production.
Clough et al. (1980)immunoglobulinT lymphocytesT lymphocytes suppressing in vitro polyclonal immunoglobulin production can be activated by allogeneic stimuli or concanavalin A (Con A).
Waldmann et al. (1975)immunoglobulinT cellIn addition, in control studies no such suppression of immunoglobulin synthesis was seen when normal cells were co-cultured with lymphocytes from unrelated normals, patients with isolated IgA deficiency, patients with chronic lymphocytic leukemia or patients with the Sezary syndrome, a T cell leukemia nor were they inhibited when incubated with T cells from unrelated normals.
Tosato et al. (1983)IgT lymphocytesWhen D-mannose or some of its derivatives, including alpha-methyl-D-mannoside, mannose-6-phosphate, and mannan, were added to suppressed cultures containing IM T lymphocytes and pokeweed mitogen (PWM)-stimulated normal mononuclear cells, a significant enhancement of Ig production was observed.
Tosato et al. (1983)IgT cellsThe effect of sugars on Ig production by suppressed cultures was similar to that achieved by decreasing by about fourfold the number of IM T cells in culture.
Tosato et al. (1983)IgT cellsThese data indicate that D-mannose and some of its derivatives consistently reverse suppression of Ig production by IM T cells and strongly suggest a role for saccharides as critical components in the cellular receptors involved in certain physiologic immune cell interactions.
Suzuki et al. (1989)immunoglobulinT-cellPeripheral blood samples collected from normal individuals and patients with benign monoclonal gammopathy (BMG) were separated and assayed for their T-cell subpopulations, PHA blast formation as well as immunoglobulin (Ig) synthesis in vitro.
Suzuki et al. (1989)IgT-cellThe distribution of values for T-cell subsets, PHA blast formation and Ig synthesis in the BMG cases more closely resembled that in the aged than that in the age-matched controls.
Yamasaki (1992)IgMT cellsInterestingly, mitomycin C (MMC)-treated patient T cells induced a greater amount of IgM production by control B cells.
Worman et al. (1978)IgMT-cellIt has been demonstrated that in two patients with T-cell S├ęzary syndrome the pathological cells express a receptor for EA(IgM) when cultured in a medium with foetal calf or autologous serum.
Kalashnikova et al. (1989)IgMT-lymphocytesIn combined immunological investigation of 24 patients with Sneddon syndrome, 16 showed the decreased content of T-lymphocytes and theophylline-sensitive cells, increased content of B-lymphocytes, increased levels of IgM and circulating immune complexes.
McKeever et al. (1985)immunoglobulinT cellThese results suggest that T cell immunoregulation is normal in patients with ALD and a defect in this system is not responsible for the increased synthesis of immunoglobulin observed in ALD.
Teodorczyk-Injeyan et al. (1986)immunoglobulinT-cellPolyclonal immunoglobulin production in burned patients--kinetics and correlations with T-cell activity.
Lahita (1992)ImmunoglobulinT-cellImmunoglobulin synthesis, T-cell subsets, and a variety of cytokines are targets for sex steroids.
Teodorczyk-Injeyan et al. (1992)IgT-cellThe majority of the patients studied demonstrated a profound suppression of the T-cell-dependent, pokeweed-mitogen-induced Ig production.
Teodorczyk-Injeyan et al. (1992)IgT lymphocytesBoth patient-derived and control TCRs failed to induce Ig synthesis in cultures of resting B cells and had comparable mitogenic effects on normal SAC-activated and phytohemagglutinin A-activated B and T lymphocytes, respectively.
Hersey et al. (1980)immunoglobulinT lymphocytesThe underlying basis for hypogammaglobulinaemia in patients with chronic lymphatic leukaemia (CLL) was investigated by measurement if immunoglobulin produced in vitro in cultures of pokeweek mitogen-stimulated B and T lymphocytes.
Hersey et al. (1980)immunoglobulinT cellsThese results suggest that immunoglobulin production by B lymphocytes from most patients with CLL was abnormal but also that T cells from CLL patients may be abnormal in respect to their role in immunoglobulin production at an early stage of the disease.
Pereira et al. (1983)IgT cellIn 11 normal adults, this enhancement of Ig production correlated with T cell-mediated cytotoxic regression.
Naito and Bito (1980)IgMT cellsT cells (IgM-T cells) of such chickens were able to help B cells to produce IgM antibody responses but were not able to help them to switch IgM- to IgG-antibody responses.
Ertel et al. (1989)IgMT-cellAddition of recombinant interleukin 2 or T-cell supernatant enhanced but did not restore IgM synthesis.
Markina et al. (1998)IgMT-lymphocytesThe studies of 116 females with chronic nonspecific salpingo-oophoritis demonstrate that combination of low-frequency magnetic field with iodine-bromine water effectively corrects immunological indices, i.e. improves T- and B-cell immunity, production of IgM and IgA, proportion of immunoregulatory subpopulations of T-lymphocytes.
Wimperis et al. (1987)IgT cellsIn contrast helper activity in the recipient T cell enriched population returns rapidly and by 6 weeks after transplant co-cultures of marrow donor B cells and recipient T cells produce comparable amounts of Ig to co-cultures of donor T and B cells.
Koopman and Schrohenloher (1980)IgMT cellIgM RF production induced by PWM was dependent upon de novo protein synthesis and exhibited T cell dependence.
Hilchey et al. (2009)immunoglobulinT cellsWe analyzed the response against the immunoglobulin expressed by the FL before and after rituximab monotherapy in 5 FL patients and found an increase in FL idiotype-specific T cells after rituximab in 4 of 5 patients.
Somech et al. (2008)immunoglobulinT-cellsImmune studies demonstrated combined humoral and cellular abnormalities including reduced immunoglobulin production, an absence of lymphoid tissue, markedly reduced T-lymphocyte numbers and function and reduced newly thymus-derived T-cells.
Ambach et al. (2003)immunoglobulinT cellsThey act as a negative regulator of activated T cells, control immunoglobulin production, contribute to the regulation of the TH1/TH2 balance, and occupy a central role in anti-viral defense mechanisms.
Paloczi (2000)immunoglobulinT-cellT-cell proliferation as well as immunoglobulin production remains impaired usually until the second half of the first year post-transplant.
Yasuda et al. (1998)immunoglobulinT cellsThe central part of the chicken germinal center contained B cells expressing immunoglobulin, follicular dendritic cells and a few T cells.
Yoshikawa et al. (1998)immunoglobulinT-cellAlthough the suppressive effects of UDCA on some cytokine productions, T-cell mediated cytotoxicity and immunoglobulin production were observed from in vitro studies, the immunomodulation in vivo by UDCA remains unclear.
Reinert et al. (1994)immunoglobulinT-cellsImmunological investigations showed a reduction in immunoglobulins, a decrease in in vitro immunoglobulin synthesis and a disorder of immunoregulatory T-cells, but immunological changes could not be readily explained by splenectomy alone.
Palacios et al. (1991)immunoglobulinT cellThese data disagree with the hypothesis than GMHLN is due to a deficiency of the T cell suppressive function with concomitant immunoglobulin over-production.
Jakobiec et al. (1987)immunoglobulinT-lymphocytesMolecular genetic (genotypic) analysis elucidates gene rearrangements within lymphocytes that are responsible for either immunoglobulin production in B-lymphocytes or the expression of cell-surface antigen recognition receptors in T-lymphocytes.
Birx et al. (1986)immunoglobulinT cellsInstead, the patients' T cells markedly increased immunoglobulin production induced by EBV.
Dixon et al. (1984)immunoglobulinT cellSporadic ovine lymphoma cells were identified as T or B lymphocytes with a T cell-specific antiserum or by detecting surface immunoglobulin.
Oshimi et al. (1984)immunoglobulinT-cellA case report of T-cell lymphoma with suppressor phenotype and helper function for immunoglobulin synthesis.
Oshimi et al. (1984)immunoglobulinT-cellAs far as we know, this is the first report on T-cell lymphoma having suppressor phenotype and helper function for immunoglobulin synthesis.
Brenner et al. (1984)immunoglobulinT cellsWhen hypogammaglobulinaemia occurs in association with thymoma, then B cell numbers have been reported as low, and distinctive T cells are present which inhibit immunoglobulin production by normal cells.
Reinherz et al. (1981)immunoglobulinT cellsIn mixing experiments, her T cells did not induce immunoglobulin secretion by B cells from a normal, HLA-D-identical sibling; this failure was not due to excessive suppression, since the patient's T cells did not abrogate immunoglobulin production by the normal sibling's T and B cells.
Edelson (1977)immunoglobulinT cellsThe abnormal T cells, which in these malignancies appear to be derived from normal "helper" T cells, which facilitate immunoglobulin production by normal B cells.
Yamasaki (1992)IgMT cellsThe surface IgM positive B cells were present at almost the same percentage as in controls, but the percentage of cluster of differentiation (CD)4+ T cells was higher and that of CD8+ T cells was low.
Bell and Wigzell (1977)IgT cellA battery of specific anti-Ig reagents as well as supposed B and T cell-specific mitogens were used, and DNA synthesis as well as high-rate Ig synthesis in vitro were recorded.
Raziuddin and Danial (1988)IgMT cellThis deficiency of helper/inducer T cell subsets in blood was associated with impaired T cell responses to phytohaemagglutinin in vitro, and an impaired ability to produce IgA and IgM by the patient's B cells.
Raziuddin and Danial (1988)IgMT cellThe patient's OKT4+ (CD4+) T cell deficient population suppressed IgM synthesis by normal B and T cells.
Singh and Goel (2000)IgMT cellsLevels of IgG, IgA, IgM, T cells and CICs were significantly raised in fresh and healed tuberculosis patients, compared to control.
Dickinson et al. (1986)IgMT lymphocytesSynthesis of IgM but not IgG induced by PWM was subnormal after addition to patient B-cell cultures of autologous irradiated T cells or allogeneic irradiated normal T lymphocytes.
Dickinson et al. (1986)immunoglobulinT-cellOur results suggest that in HD impaired circulating B-cell function is partly due to T-suppressor cell activity and furthermore that B-cell subpopulations producing different immunoglobulin isotypes may either be defective or vary in their susceptibility to T-cell suppression.
Handzel et al. (1977)immunoglobulinT cellIt is speculated that the T system deficiency may have been acquired following Epstein-Barr virus infection, and that T cell regulatory activity of immunoglobulin production was defective.