Viewing affirmative mentions of gene expression of IL2 (H. sapiens)

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Ketzinel et al. (1991)interleukin-2suppressor T lymphocytesRegulation of human interleukin-2 and interferon-gamma gene expression by suppressor T lymphocytes.
Ting et al. (1984)IL 2suppressor T cellsThese suppressor T cells could be induced by rat (spleen)-produced, murine (EL-4 cells) produced IL 2 preparations, and a purified human recombinant IL 2 (HR-IL2).
Ting et al. (1984)IL 2suppressor T cellWhen higher levels of IL 2 were produced later, the suppressor T cell precursors were activated and differentiated into suppressor effectors to regulate the CTL response.
Morgan et al. (1985)IL 2suppressor T cellsHowever, neither C3a nor C3a-generated suppressor T cells can block the synthesis of IL 2.
Kirkpatrick et al. (1985)IL-2suppressor T lymphocytesThe titer of IL-2 produced by the AIDS patients correlated with the percentage of helper T lymphocytes (Leu 3a+ cells) but not with the percentage of suppressor T lymphocytes (Leu 2a+ cells).
Marchiol et al. (1985)IL 2suppressor T lymphocytesA negative control of IL 2 production involving monocytes producing PGE 2 able to induce radiosensitive suppressor T lymphocytes, has been identified previously with cells from healthy donors.
Leclerc et al. (1984)IL 2suppressor T cellFrom these data we propose that at least two independent pathways in the regulation of human IL 2 production exist: a one-signal pathway already described in which PGE2 directly triggers a radiosensitive suppressor T cell subset; and a second pathway with two signals, one given by PGE2 and a second one given by agents such as muramyl peptides.
Loertscher et al. (1988)interleukin 2suppressor T lymphocytesBlocking of T cell activation at the G1A/G1B interface of the cell cycle and prevention of expression of interleukin 2 receptors by alloactivated suppressor T lymphocytes.
Rodrick et al. (1986)IL 2suppressor T cellsThese results suggest that the cause of the defect in IL 2 production in traumatic injury patients is not related to a lack of the IL 1 signal, producer T cells, or Ia+ monocytes or to increased suppressor T cells.
Kawano et al. (1990)IL2suppressor T cellsTaken together, these data suggest the requirement of exogenous IL2 for IL2 production in that IL2-producing-precursor T cells themselves should be stimulated by IL2 in addition to the modulation of CD45R+ suppressor T cells by IL2.
Oh-Ishi et al. (1989)IL-2suppressor T cellsIn summary, our studies indicate that anti-Tac, by producing a functional blockade of human IL-2 receptors, inhibits the generation of suppressor T cells in antigen-specific as well as antigen-nonspecific systems and that cells that no longer express the Tac antigen may also function as suppressors.
Oh-Ishi et al. (1988)IL-2suppressor T cellsOur studies indicate that anti-Tac, by producing a functional blockade of human high-affinity IL-2 receptors, inhibits the generation of antigen-nonspecific suppressor T cells.
Okimoto et al. (1994)IL-2suppressor T cellsInhibition of IL-2 synthesis by donor-specific suppressor T cells in a renal transplant recipient.
Yoshikawa et al. (1995)IL-2suppressor T lymphocytesWe have investigated the effects of interleukin-2 (IL-2) on the activation of suppressor T lymphocytes in autoimmune thyroid disease (AITD), with insulin-dependent diabetes mellitus (IDDM) as an autoimmune disease control; this was accomplished by measuring the expression of major histocompatibility complex class II (HLA-DR), CD25 (IL-2 alpha receptor (R)), and IL-2 beta R expression on their surfaces by flow cytometric analysis.
Susskind et al. (1983)interleukin 2suppressor T cellLevels of endogenous interleukin 2 (IL 2) in co-cultures with suppressor T cells were diminished, and the addition of exogenous IL 2 to co-cultures cancelled the suppressor T cell effects.
Attia et al. (2005)IL-2regulatory T lymphocytesThis study examined the ability of a fusion protein of interleukin-2 (IL-2) and diphtheria toxin (Denileukin Diftitox, DAB389IL-2, ONTAK) to eliminate regulatory T lymphocytes based on their expression of high-affinity IL-2 receptors.
Koyama et al. (1985)IL-2-dependentsuppressor T-cellsThese findings suggest that generation of IL-2-dependent suppressor T-cells is the result of large tumor burdens; this may exert negative cellular control in the immune responses, thus inducing the status of the lower cell-mediated antitumor immunity, and may promote cancer progression in gastric cancer patients.
Mustafa (1995)IL-2suppressor T cellsMycobacterium bovis BCG-induced Th1 type CD4+ suppressor T cells act by suppressing IL-2 production and IL-2 receptor expression.
Long et al. (2010)IL-2regulatory T-cellsHowever, no link between IL-2 responsiveness and CD4(+)CD25(+)FOXP3(+) regulatory T-cells (Tregs) has been demonstrated in type 1 diabetic subjects despite the role of these IL-2-dependent cells in controlling autoimmunity.
Hosotani et al. (1993)IL-2suppressor T cellsPathogenesis of aortitis syndrome is considered as follows: during the active stage, diminished IL-2 production impairs differentiation and proliferation of suppressor T cells, thus creating abnormalities in the inhibitory functions of immunoregulation and promoting the proliferation of cytotoxic T and natural killer (NK) cells.
Ertel et al. (1990)IL-2suppressor T-lymphocytesAlthough it is known that mitogen-induced lymphocyte proliferation and interleukin-2 (IL-2) synthesis are depressed following mechanical trauma, it is not known whether these defects are due to high levels of circulating prostaglandin E2 released by macrophages, suppressor T-lymphocytes, and serum suppressive factors or due to intracellular defects in T-lymphocytes.
Attia et al. (2005)IL-2regulatory T lymphocytesInability of a fusion protein of IL-2 and diphtheria toxin (Denileukin Diftitox, DAB389IL-2, ONTAK) to eliminate regulatory T lymphocytes in patients with melanoma.
Nanda et al. (1994)lymphokinesuppressor T cellA unique pattern of lymphokine synthesis is a characteristic of certain antigen-specific suppressor T cell clones.
D'Cruz and Klein (2005)interleukin 2suppressor T cellsWe found that the differentiation, acquisition of functional capacity and formation of a sizeable pool of suppressor T cells in the thymus was independent of interleukin 2 signaling, but that interleukin 2 was essential for the survival of mature Foxp3(+) regulatory T cells.
Yvon et al. (2003)interleukin-2regulatory T-cellStimulation of CD45RA+ naive T cells by Jagged-1 EBV-LCL reduces production of interferon-gamma, interleukin-2, and interleukin-5, but up-regulates transforming growth factor-beta 1 synthesis, consistent with induction of a regulatory T-cell phenotype.
Minai et al. (1994)lymphokinesuppressor T cellIn a previous study, we established CD8+ suppressor T cell (Ts) clone 13G2 which produced the suppressive lymphokine, interleukin-10 (IL-10).
Verselis and Goust (1987)IL-2suppressor T cellIt suggests that the deficiency of suppressor T cell functions postulated to play a role in MS does not arise from a lack of IL-2 induction and might indicate that bursts of IL-2 production could play a role in MS.
Morin and Ballet (1982)lymphokinesuppressor T cellThe agent, somehow mimicking the effects of thymic factors, induces the appearance of phenotypic markers of differentiation on immature precursor T cells; enhances the proliferative response of murine and human lymphocytes to mitogens or antigens, augments helper or suppressor T cell functions and increases the production of lymphotoxin a lymphokine.
Zeiser et al. (2006)interleukin-2regulatory T-cellInhibition of CD4+CD25+ regulatory T-cell function by calcineurin-dependent interleukin-2 production.
Gerez et al. (1991)IL-2suppressor T cellCulture conditions were chosen that measure the transient, phytohemagglutinin-induced expression of IL-2 and IFN-gamma messenger RNA (mRNA), as well the intactness of post-transcriptional and suppressor T cell-dependent mechanisms that control this expression.
Gerez et al. (1991)IL-2suppressor T cellCulture conditions were chosen that measure the transient, phytohemagglutinin-induced expression of IL-2 and IFN-gamma mRNA, as well as the intactness of post-transcriptional and suppressor T cell-dependent mechanisms that control this expression.
Fischer et al. (1985)interleukin 2-producingsuppressor T lymphocytesTwo possible mechanisms of PGE2-mediated suppression have been proposed: one is a direct inhibitory effect exerted on interleukin 2-producing T cells; the second is mediated by the activation of nonspecific suppressor T lymphocytes.
Streitz et al. (2008)IL2regulatory T-cellsFurthermore, dominant expression of type-1 (IFNgamma, IL2, IL27 and T-bet) and of cytotoxic T-cell markers (Perforin and Granzyme B) was found, whereas gene expression indicating type-2 (IL4, GATA3) and regulatory T-cells (FoxP3) was low.
Sawalha (2008)IL-2regulatory T-cellIn this review, we focus on epigenetics in T helper cell differentiation, regulatory T-cell function, and IL-2 production.
Bottema et al. (2010)IL2regulatory T-cellOBJECTIVE: To evaluate main effects and gene-gene interactions of haplotype tagging single nucleotide polymorphisms of genes involved in regulatory T-cell function-IL6, IL6R, IL10, heme-oxygenase 1 (HMOX1), IL2, Toll-like receptor 2 (TLR2), TGFB1, TGF-beta receptor (TGFBR)-1, TGFBR2, IL2RA, and forkhead box protein 3 (FOXP3)-in relation to atopy and asthma.
Hirohata et al. (1995)IL-2suppressor T cellsThe enhancement of the suppressive activity of CD4+ suppressor T cells by PMN is accounted for by the enhancement of the endogenous IL-2 production by anti-CD3-stimulated CD4+ T cells.
Hahm et al. (1995)interleukin-2suppressor T-lymphocyteThe proposed mechanism of the immunomodulative effects of H2-RA has been considered to be the inhibition of suppressor T-lymphocyte activity, an increase in interleukin-2 production, and an enhancement of natural killer cell activity.
Loertscher (1988)interleukin 2suppressor T cellsDissociated expression of receptors for interleukin 2 and transferrin in the presence of preformed suppressor T cells and interleukin 2.