Viewing negative mentions of gene expression in T cells

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Burnier et al. (2010)Gas6T cellsGrowth arrest-specific gene 6 (Gas6) is expressed in antigen-presenting cells and endothelial cells (ECs) but not in T cells.
Sleckman et al. (2000)Pb99T cellsThe Pb99 gene is specifically expressed in pre-B cells and thymocytes and not in mature B and T cells or nonlymphoid tissues, implying that it may function in early lymphoid development.
Lechner et al. (1996)CD95T cellsResting T cells did not express CD95.
Willett et al. (2003)CXCR4T lymphocytesWhile monocytes and B lymphocytes expressed CXCR4, no CXCR4 was detected on T lymphocytes, in stark contrast to the expression pattern on T lymphocytes from humans.
Kaukonen et al. (1999)EmtT-cellIn hematopoietic cells, expression of the EMT gene was associated with T-cell fractions, but Emt was not detected in cord blood CD34+ cells.
Kaukonen et al. (1999)ItkT-cellIn conclusion, Emt (Itk) is T-cell associated both in normal and leukemic cells, but is not expressed in cord blood CD34+ cells, suggesting that Emt expression is switched on only later in T-cell development.
Sakata et al. (2004)MMP9T-cellOverall survival rates of T-cell/NK-cell lymphoma patients who expressed MMP9 appeared to be lower than that in those who did not express MMP9.
Nakano et al. (1990)CD45T cellHuman T cell leukemia/lymphoma virus type I (HTLV-I)-associated T cell lines derived from peripheral blood leukocytes of patients with adult T cell leukemia/lymphoma (ALT/L) in Japan did not express CD45 on their cell surface.
Simon et al. (1996)FasT cellsCD4-CD8- T cells from both patients, although highly activated, did not express functional Fas receptors.
Peh et al. (2001)TARCT-cellTARC, a CC chemokine, is frequently expressed in classic Hodgkin's lymphoma but not in NLP Hodgkin's lymphoma, T-cell-rich B-cell lymphoma, and most cases of anaplastic large cell lymphoma.
Reul et al. (1997)CD40T-cellRESULTS: CD40 was expressed at low levels, and CD40L was minimal or absent in histologically normal biopsies in the absence of CD3+ T-cell infiltrates.
Mack et al. (2002)HexT cellsThe haematopoietic homeobox gene Hex (also called Prh) is expressed in myeloid cells and B cells but not T cells.
Welniak et al. (2004)CCR5T-cellIn a murine transplant model with intensive conditioning, the overall effect of absent CCR5 expression on donor cells results in greater GVHD and donor T-cell expansion.
Green et al. (1991)SCL mRNAT-cellAlthough SCL mRNA is not detectable in normal thymocytes or peripheral T-lymphocytes, transcriptional activation occurs in T-cell tumours.
Weigent et al. (1984)IFNT-cellIn contrast, cocultivation of enriched T-cell populations with mouse L cells resulted in no IFN production or transfer of antiviral activity.
Gilman et al. (1982)IL-2T lymphocytesIn allogeneic MLTC, "old" T lymphocytes produce little IL-2 compared with "young" cells, and both "young" and "old" cells respond to exogenous IL-2 with enhanced 3H-TdR uptake and increased cytotoxic activity.
Wang et al. (2003)PDE9A1T cellsBy Western blot analysis, native PDE9A1 is detectable in the nucleus but not in the cytoplasm of T cells.
Viallard et al. (2000)cyclin B1T cellsThe detection of cyclin B1 by Western blot in cells sorted in the G(1) phase of the cell cycle showed that cyclin B1 was present in the G(1) phase in leukemic T cells but not in normal T lymphocytes.
Viallard et al. (2000)cyclin B1T cellsOur data support the notion that human cyclin B1 is present in the G(1) phase of the cell cycle in leukemic T cells but not in normal T lymphocytes.
Chilosi et al. (2003)p63T-cellAmong lymphomas, T-cell-precursor lymphomas did not express p63, whereas most PMLBCL expressed TA-p63alpha (7/8).
Wurbel et al. (2006)CCR9T cellsIn the periphery, functional CCR9 is expressed by all naive CD8 T cells, but not by naive CD4 T cells.
Rocha et al. (1989)IL2T cellsThe results obtained show that mature T cell growth in vivo is not accompanied by expression of high-affinity interleukin 2 (IL2) receptor in the majority of activated cells, is not abrogated by in vivo administration of anti-IL2 receptor antibodies or enhanced by the in vivo injection of recombinant IL2, and that in vivo growing T cells do not produce detectable amounts of IL2, as evaluated functionally by limiting dilution assays or the presence of IL2 mRNA, detected by Northern blots or in situ hybridization.
Brennan and Jongstra (1996)LSP1T-cellsHere we show by Northern analysis that three mature antigen independent T-cell lines (CTLL-2, HT-2 and 532.10) which grow in the presence of lymphokine only, do not express LSP1 RNA, while mature resting and activated lymph node T-cells express high levels of LSP1 RNA.
Liu et al. (1998)CTLA-4T cellsBut patients with SLE had significantly increased percentages of CTLA-4-positive T cells compared with normal controls, implying at least that there was no apparent defective expression of CTLA-4 molecule in human lupus.
Marr et al. (2005)CD91T cellsRT-PCR study reveals that CD91 is expressed in most cell types, including adult macrophages, B and T cells as well as in splenocytes and thymocytes from naturally MHC class I negative larvae.
Köhler et al. (1977)Thy 1T-cellNo hybrids between the myeloma line and spleen T cells were identified as none of the hybrids expressed the T-cell-specific antigen Thy 1.
Vidal-Rubio et al. (2001)CD69T cellsTwo populations of T cells, which are either negative for CD69 or express it in bright levels (CD69bright), were also found.
Halin et al. (2005)S1P1T-cellThus, FTY720 exerts unique effects on T-cell traffic in PPs that are independent of T-cell-expressed S1P1.
Zupo et al. (1994)CD5T cellsResting CD5- B cells failed to express CD5 and/or CD38 when cultured with PMA in the presence of EL4 T cells and IL-4-free T cell supernatants.
Hegen et al. (1993)CD26T cellIn Jurkat T cell leukemia cells that normally do not express the CD26 antigen, the transfected CD26 molecule is functional because the monoclonal antibody CB.1 induces an increase of cytosolic Ca2+ concentration and IL-2 production.
Schlotmann et al. (2000)CTLA-4T cellsAfter initiation of antiplasmodial treatment, it returned to control values within a few days. gammadelta T cells, which also are implicated in the pathogenesis of human malaria, did not express CTLA-4.
Karamitros et al. (2010)GemininT cellsT cells lacking Geminin expression upregulate early activation markers efficiently upon TCR stimulation in vitro and are able to enter the S phase of cell cycle, but show a marked defect in completing the cycle, leading to a large proportion of T cells accumulating in S/G2/M phases.
Sing et al. (1990)TGF-betaT-cellBinding and cross-linking with radioiodinated TGF-beta 1 demonstrated either low or absent expression of all three TGF-beta receptor species on three B-cell tumor lines, but T-cell and non-T, non-B tumors expressed large numbers of receptors.
Benschop et al. (2009)DR6T-cellIn the absence of DR6, ligation of the TCR results in enhanced T-cell proliferation, activation and skewed Th2 cytokine production.
Müller-Quernheim et al. (1986)IL 2 geneT cellsThe sarcoid lung T cells, however, did not express the IL 2 gene constitutively; when placed in culture with no stimulation and evaluated after 24 hr, they demonstrated down regulation of the amounts of IL 2 mRNA transcripts, despite the fact that they were capable of re-expressing the IL 2 gene and releasing more IL 2 in response to added activation signals.
Fischbach and Talal (1985)interleukin-2T cellAutoimmune mice bearing the single autosomal recessive gene 1pr are unable to produce the T cell growth factor, interleukin-2 (IL-2).
Oh-Hori et al. (1990)p56lckT-cellHuman T-cell leukemia virus type-I-infected T-cell lines scarcely produce p56lck, whether or not they express lck mRNA.
Oh-Hori et al. (1990)p56lckT-cellUsing this antiserum, we show that HTLV-I-positive T-cell lines, whether they are IL-2-dependent or not, scarcely express p56lck.
Cutrona et al. (1999)CD10T-cellCells from continuous T-cell lines did not normally express CD10, but became CD10(+) when induced into apoptosis by human immunodeficiency virus (HIV) infection and exposure to CD95 monoclonal antibody, etoposide, or staurosporin.
Beavitt et al. (2005)LynT cellsLyn tyrosine kinase has been implicated as both a facilitator and inhibitor of signaling pathways that play a role in allergic inflammation, although its role in asthma is unclear because Lyn is not expressed in T cells.
Gloire et al. (2007)SHIP1T-cellsJurkat cells have recently emerged as an interesting tool to study SHIP1 function in T-cells because they do not express SHIP1 at the protein level, thereby allowing reintroduction experiments in a relatively easy-to-use system.
Somers et al. (1998)P2Y6T cellsISH results reveal that P2Y6 is highly expressed in the T cells infiltrating active IBD, whereas P2Y6 expression was absent from the T cells of unaffected bowel.
Wilson et al. (1993)CD74T cellsHowever, allostimulated T cells which express de novo induced class II determinants also did not express CD74.
Wilson et al. (1993)CD74T-cellTaken together, these results show that CD74 is expressed on B cells and unexpectedly is not synthesized on de novo-induced class II positive T-cell clones.
Iwaki-Egawa et al. (1995)CD26T cellsCD26 expression and DPP IV enzyme activity are increased on T cells following their activation; nevertheless, no CD26 was expressed on T cells of DPP IV- rats, and no DPP IV enzyme activity was detected either before or after mitogen activation.
Chamberlain et al. (2000)CD28T cellWe noted that in most cases the expanded clones were dominated by cells that did not express CD28, a pivotal molecule in T cell activation, and these clones proliferated poorly in culture.
Villiger et al. (1991)IL-6T cellAnalysis of purified T-alpha beta and T-gamma delta cells showed that neither T cell subset produced IL-6.
Villiger et al. (1991)IL-6T cellIn contrast, IL-6 was not detectable in non-infected T cell lines.
Croxson et al. (1988)p24T-lymphocyteHIV p24 was expressed in three of seven patients in response to AA but not to the T-lymphocyte mitogen phytohemagglutinin.
Stachowski et al. (2000)MDR1T-cellNegative control, Jurkat-T-cell line, not expressing the MDR1 phenotype, was transfected with viral expression vector containing a full-length cDNA for the human MDR1 gene.
Kobayashi et al. (1989)IL-2T cellThe antigen-reactive T cell line produces neither IL-2 nor inhibiting factors such as neutralizing factors against preformed IL-2 activity and IL-2 production inhibiting factors, thus the cells are exclusive IL-2 acceptor.
Wilson et al. (2000)CD4T cellsIn contrast, HIV-1-specific proliferative responses were absent in most individuals with progressive HIV-1 infection, even though interferon-gamma-producing HIV-1-specific CD4(+) T cells were detectable by flow cytometry.
Narducci et al. (2000)TCL1T-cellConversely, TCL1 was not expressed in Hodgkin/Reed-Sternberg cells, multiple myelomas, marginal zone B-cell lymphomas, CD30+ anaplastic large cell lymphoma, lymphoblastic T-cell lymphoma, peripheral T-cell lymphoma, and mycosis fungoides.
Yücel et al. (2004)Gfi1T-cellGfi1 is absent in mature B-cells, whereas in peripheral T-cells Gfi1 gene expression is low but rises significantly upon T-cell receptor triggering and decreases again in T-memory cells.
Ferrero et al. (2004)CD38T cellTo test this possibility, we analysed reactivity of these mAbs with the CD38-negative MT2 human T cell line stably transfected with CD38?
Beisner et al. (2003)FADDT cellsUsing T cells from mice expressing a dominant negative form of FADD (FADDdd), activation with anti-TCR Ab and costimulation or exogenous cytokines is profoundly diminished.
Schall et al. (1988)RANTEST cellInterestingly, RANTES was not expressed by any T cell tumor line tested.
Erman et al. (2002)TCRalphaT cellClonotypic T cell receptor (TCR) genes undergo ordered rearrangement and expression in the thymus with the result that TCRalpha and TCRgamma proteins are not expressed in the same cell at the same time.
Fangmann et al. (1991)RT6T cellsIn the DP BB rats the number of LN T cells was substantially reduced (less than 25% TcR2+ cells) and completely lacked RT6 expression.
Waldmann et al. (1985)IL-2T-cellsResting T-cells do not express IL-2 receptors, but receptors are rapidly expressed on T-cells following interaction of antigens, mitogens, or monoclonal antibodies with the antigen-specific T-cell receptor complex.
Waldmann et al. (1985)IL-2T-cellNormal resting T-cells and most leukemic T-cell populations do not express IL-2 receptors; however, the leukemic cells of the 11 patients examined who had human T-cell lymphotropic virus-associated adult T-cell leukemia expressed the Tac antigen.
Pittet et al. (2000)CD56T cellsCD56 was absent on cord blood CD8+ T cells, but was expressed by 4-30% of freshly isolated circulating CD8+ T cells from 15 adults.
Chilosi et al. (1996)CD30T lymphocytesLarge proportions of tissue-infiltrating T lymphocytes from all four patients expressed CD30, whereas in control tissues, including peripheral blood, CD30+ T lymphocytes were extremely few or absent.
Shichijo et al. (1995)MAGE geneT cellIn summary, the MAGE gene family was found to be expressed in the substantial proportion of T cell leukemias, but in no case of myelomonocytic leukemia.
Tsuji et al. (2004)CD26T-cellMalignant cells often show altered CD26/DPPIV expression or no CD26/DPPIV expression, thus suggesting a useful marker for assessing some T-cell malignancies.
Brown et al. (1989)CD2T-cellThus, mutant T-cell lines expressing CD2, but not Ti-CD3, on the cell surface cannot be activated via the CD2 molecules.
Sung et al. (2005)CD99T cellIn conclusion, CD99 is infrequently expressed in mature B and T cell lymphomas, except ALK-positive ALCL.
Xerri et al. (1997)CTLA4T-cellCTLA4 was present in neoplastic cells from most (10/11) T-cell malignancies, except for anaplastic and lymphoblastic subtypes (0/4).
Hatada et al. (2005)IFN-gammaT cellsNylon wool-purified "T cells", however, failed to produce IFN-gamma in response to Con A in vitro, while the production was restored by the addition of neutrophils.
Fargnoli et al. (1995)SykT cellDuring the course of experiments examining signals initiated by the T cell antigen receptor in an E6-1-derived Jurkat cell clone J.CaM1, we observed that the 72-kilodalton Syk protein tyrosine kinase previously found in other Jurkat cells was not detected.
Wiskocil et al. (1985)IL 2T cellIn the resting state, the T3-positive, human T cell line Jurkat does not synthesize detectable amounts of either interleukin 2 (IL 2) or gamma-interferon (IFN-gamma).
Robinson et al. (1997)CD72T cellsIn this report we demonstrate that CD72 is constitutively expressed on a fraction of peripheral T cells isolated from strains of mice expressing the CD72(b) allele, but not the CD72(a) or CD72(c) alleles.
Rosenkranz et al. (2000)IgGT-cellIn gammadelta T-cell-deficient mice, circulating levels and glomerular deposition of autologous IgG were comparable to wild-type levels, while alphabeta T-cell-deficient mice had no autologous IgG production.
Andjeli? et al. (1994)FasT cellFas was not expressed on fetal nor adult CD8-CD4- (double-negative, DN) T cell precursors.
Libri et al. (2008)Jakmip1T cellsJakmip1 is absent in naive CD8(+) and CD4(+) T lymphocytes from peripheral blood but is highly expressed in Ag-experienced T cells.
Ando et al. (1988)IFN-gammaT-cellThese results indicate that the myelomonocytic HBL-38 cells, not a T-cell line, can also produce IFN-gamma identical to the product of normal human PBL.
Sponaas et al. (1988)H-2 class IT-cellHowever, EC cells express no H-2 class I antigens in vitro, and for in vivo rejection by T-cell responses directed either at allogeneic class I molecules or at minor H antigens restricted by self class I molecules, one would need to postulate that EC cells growing in vivo could express sufficient class I antigens for recognition by T cells.
Lopez-Cepero et al. (1988)IL-2T lymphocytesSpleen cell populations enriched for T lymphocytes and depleted of tumor cells by density gradient centrifugation in Ficoll were unable to produce IL-2.
Jokhi et al. (1995)CSF-1T cellsThe major sources were observed to be decidual stromal cells and decidual CD56+ natural killer (NK) cells, but decidual CD3+ T cells did not produce CSF-1, reflecting functional differences between these two decidual lymphoid populations.
Prazma et al. (2007)CD83T cellsIn primary and secondary lymphoid compartments, a subset of B cells expressed low-level CD83, while CD83 was not detected on resting T cells.
Bacchetta et al. (2006)FOXP3 proteinT cellsIn contrast, the suppressive function of CD4+ CD25high T cells from IPEX patients who do not express FOXP3 protein was profoundly impaired.
Lübbert et al. (1989)p53T-lymphocytesResting T-lymphocytes from these same individuals did not express p53.
Ozkal et al. (2009)FAKT-cellIn human lymphomas, FAK was expressed mostly in B-cell lymphomas and was predominantly negative in T-cell lymphoma.
Park and Oh (2005)p63T-cellChilosi et al. (25) reported that T-cell precursor lymphomas did not express p63, whereas 7 of 8 cases of PMLBCL expressed TA-p63?.
Ohta et al. (1990)lckT-cellThe T-lymphocyte-specific tyrosine kinase gene, lck, is expressed in T-lymphocyte cell lines, except for several human T-cell leukemia virus type I(HTLV-I)-transformed T-lymphocyte cell lines, which produce HTLV-I.
Waldmann et al. (1984)IL-2T cellsResting T cells do not express IL-2 receptors but receptors are rapidly expressed on T cells following the interaction of antigens, mitogens, or monoclonal antibodies with the antigen specific T-cell receptor complex.
Waldmann et al. (1984)IL-2T-cellNormal resting T cells and most leukemic T-cell populations do not express IL-2 receptors however the leukemic cells of all patients with human T-cell leukemia/lymphoma virus (HTLV-I) associated, adult T-cell leukemia (ATL) examined expressed the Tac antigen.
Bobryshev et al. (1998)E-cadherinT-cellsT-cells (CD3+) and endothelial cells (von Willebrand factor+) were also negative for E-cadherin.
Garnett and Williams (1994)CD48T cellsThe clusters were found to be due to homotypic adhesion of B cells, with T cells showing no response despite expressing equal levels of CD48.
Inoue et al. (1999)IL-4T-cellsIL-4 was not detected in the serum of CD4+ T-cells-depleted mice.
Seroogy et al. (2004)GRAILT cellsConstitutive expression of GRAIL was sufficient to render naive CD4 T cells anergic, however, when the enzymatically inactive form H2N2 GRAIL was expressed, it functioned as a dominant negative of endogenous GRAIL and blocked the development of anergy.
Dahlén et al. (1998)TNF-alphaT cellsHowever, on immunohistochemical analysis of TNF-alpha expression in islets, we are able to show that the staining pattern of TNF-alpha resembles that of dendritic cells (DC) and macrophages (Mphi) rather than T cells and that TNF-alpha is expressed in islets at the very early stages of insulitis when no T cells are detected.
Sung et al. (1997)IFN gammaT cellsBecause IFN gamma is synthesized by activated T cells, but not by keratinocytes, these results suggest that Fas may only be effective in apoptosis occurring in T-cell mediated inflammatory skin diseases.
Flo et al. (2001)TLR2T-cellsIn human blood, CD14+ monocytes expressed the highest level of TLR2 followed by CD15+ granulocytes, and CD19+ B-cells, CD3+ T-cells, and CD56+ NK cells did not express TLR2.
Steeg et al. (1995)CD26T cellsThe response of transfected clones to direct stimulation with anti-CD26 antibodies and to costimulation via CD26 was variable and not solely dependent on the amount of CD26 and T cell receptor expressed on the T cells.
Sonnenberg et al. (2010)IL-17AT cellsIn contrast, subsets of gut-resident NK cells and skin-resident CD4+ T cells are reported to express IL-22 but do not coexpress IL-17A (Satoh-Takayama et al., 2008; Cella et al., 2009; Duhen et al., 2009; Trifari et al., 2009).